(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA] CTD PMID:31150632 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o and p'-DDT affects the expression of AKR7A2 mRNA CTD PMID:17984292 1,2-dimethylhydrazine increases expression ISO Akr7a5 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA] CTD PMID:22206623 1,2-naphthoquinone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 1 and 2-naphthoquinone CTD PMID:10510318 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO AKR7A2 (Homo sapiens) 6480464 14-deoxy-11 and 12-didehydroandrographolide results in decreased expression of AKR7A2 mRNA CTD PMID:22101062 16-Ketoestrone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of AKR7A5 mRNA CTD PMID:16926038 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of AKR7A2 mRNA CTD PMID:26496021 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:21394737 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR7A2 mRNA CTD PMID:18796159 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR7A2 mRNA CTD PMID:32109520 and PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Akr7a5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR7A5 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Akr7a5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR7A5 mRNA CTD PMID:19465110 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of AKR7A2 mRNA CTD PMID:21346803 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:19954255 2-methylcholine affects expression ISO AKR7A2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of AKR7A2 mRNA CTD PMID:21179406 2-nitrobenzaldehyde increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 2-nitrobenzaldehyde CTD PMID:10510318 2-nitrobenzaldehyde affects reduction ISO Akr7a5 (Mus musculus) 6480464 2-nitrobenzaldehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 3,3',5,5'-tetrabromobisphenol A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of AKR7A2 protein CTD PMID:31675489 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of AKR7A2 mRNA CTD PMID:30071829 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of AKR7A2 protein CTD PMID:34915118 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1 and 2-dithiol-3-thione results in increased expression of AKR7A2 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression ISO Akr7a5 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of AKR7A5 mRNA CTD PMID:18648102 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of AKR7A2 mRNA CTD PMID:21346803 4-hydroxynon-2-enal decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22001351 4-hydroxynon-2-enal affects response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:30849339 4-hydroxynon-2-enal increases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22964423 4-hydroxynon-2-enal multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] and AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 and PMID:30849339 4-hydroxynon-2-enal increases expression ISO AKR7A2 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of AKR7A2 mRNA and 4-hydroxy-2-nonenal results in increased expression of AKR7A2 protein CTD PMID:22964423 and PMID:30849339 4-nitrobenzaldehyde multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] more ... CTD PMID:12604212 4-nitrobenzaldehyde affects reduction ISO Akr7a5 (Mus musculus) 6480464 4-nitrobenzaldehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of AKR7A2 mRNA CTD PMID:19483382 7,12-dimethyltetraphene multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of 9 more ... CTD PMID:21910479 9,10-phenanthroquinone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 9 and 10-phenanthrenequinone CTD PMID:10510318 9,10-phenanthroquinone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of 9 and 10-phenanthrenequinone CTD PMID:21910479 9,10-phenanthroquinone affects reduction ISO Akr7a5 (Mus musculus) 6480464 9 and 10-phenanthrenequinone affects the reduction of AKR7A5 protein CTD PMID:12604212 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of AKR7A2 mRNA CTD PMID:31881176 acrolein multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR7A2 mRNA CTD PMID:32699268 acrylamide decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of AKR7A2 mRNA CTD PMID:32763439 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of AKR7A2 mRNA CTD PMID:22545673 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of AKR7A2 mRNA CTD PMID:23630614 Aflatoxin B2 alpha decreases methylation ISO AKR7A2 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of AKR7A2 3' UTR CTD PMID:30157460 alpha-pinene multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR7A2 mRNA CTD PMID:32699268 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AKR7A2 mRNA CTD PMID:16483693 antimycin A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Antimycin A results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 aristolochic acid A increases expression ISO AKR7A2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of AKR7A2 protein CTD PMID:33212167 Aroclor 1254 decreases expression ISO Akr7a5 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of AKR7A5 mRNA CTD PMID:23650126 azoxystrobin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 azoxystrobin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 benzo[a]pyrene-7,8-dione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 more ... CTD PMID:21910479 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of AKR7A2 mRNA and beta-Naphthoflavone results in increased expression of AKR7A2 protein CTD PMID:19389873 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of AKR7A2 mRNA CTD PMID:26496021 bisphenol A decreases expression ISO Akr7a5 (Mus musculus) 6480464 bisphenol A results in decreased expression of AKR7A5 mRNA CTD PMID:35598803 bisphenol A multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of AKR7A2 gene CTD PMID:31601247 bisphenol A decreases methylation ISO AKR7A2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of AKR7A2 gene CTD PMID:31601247 bisphenol A increases expression ISO Akr7a5 (Mus musculus) 6480464 bisphenol A results in increased expression of AKR7A5 mRNA CTD PMID:33221593 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKR7A2 mRNA CTD PMID:30816183 bisphenol A affects expression ISO AKR7A2 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR7A2 mRNA CTD PMID:30903817 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of AKR7A2 gene CTD PMID:28505145 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of AKR7A2 mRNA CTD PMID:25181051 bisphenol F increases expression ISO AKR7A2 (Homo sapiens) 6480464 bisphenol F results in increased expression of AKR7A2 protein CTD PMID:34186270 bortezomib multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in decreased expression of AKR7A2 mRNA CTD PMID:25522274 Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of AKR7A2 protein CTD PMID:28903499 cadmium atom multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR7A2 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR7A2 mRNA CTD PMID:35301059 CGP 52608 multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to AKR7A2 gene] CTD PMID:28238834 chenodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 chlordecone multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Chlordecone promotes the reaction [Biomarkers metabolite binds to AKR7A5 gene] CTD PMID:31084621 cisplatin increases expression ISO AKR7A2 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR7A2 mRNA CTD PMID:27594783 clofibrate decreases expression ISO Akr7a5 (Mus musculus) 6480464 Clofibrate results in decreased expression of AKR7A5 mRNA CTD PMID:17585979 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of AKR7A2 protein CTD PMID:16470657 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of AKR7A2 mRNA CTD PMID:19483382 cobalt dichloride decreases expression ISO AKR7A2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of AKR7A2 mRNA CTD PMID:19376846 copper(II) sulfate decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of AKR7A2 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AKR7A2 mRNA CTD PMID:20106945 and PMID:25562108 cyclosporin A multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 deguelin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 deguelin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 deoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of AKR7A2 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO Akr7a5 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of AKR7A5 mRNA CTD PMID:17361019 and PMID:21266533 dimethylarsinic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 dioxygen multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 doxorubicin increases metabolic processing ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 results in increased metabolism of Doxorubicin CTD PMID:20837989 doxorubicin increases phosphorylation ISO AKR7A2 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of AKR7A2 protein CTD PMID:30817976 doxorubicin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of AKR7A2 mRNA CTD PMID:30817976 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of AKR7A2 mRNA CTD PMID:29391264 epoxiconazole increases expression ISO Akr7a5 (Mus musculus) 6480464 epoxiconazole results in increased expression of AKR7A5 mRNA CTD PMID:35436446 etacrynic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 fenpyroximate decreases expression ISO AKR7A2 (Homo sapiens) 6480464 fenpyroximate results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 folic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA] CTD PMID:22206623 FR900359 increases phosphorylation ISO AKR7A2 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of AKR7A2 protein CTD PMID:37730182 fulvestrant multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of AKR7A2 gene CTD PMID:31601247 furan affects binding EXP 6480464 furan binds to AKR7A2 protein CTD PMID:22240984 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of AKR7A2 mRNA CTD PMID:33387578 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of AKR7A2 mRNA CTD PMID:24136188 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of AKR7A2 mRNA CTD PMID:15345336 glutathione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione] CTD PMID:22001351 glycochenodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 glycocholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 glycodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 hexanal decreases response to substance ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in decreased susceptibility to n-hexanal CTD PMID:24590062 hydrogen peroxide multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in increased chemical synthesis of Hydrogen Peroxide more ... CTD PMID:21910479 hydrogen peroxide decreases response to substance ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:24590062 hydrogen peroxide increases expression ISO AKR7A2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of AKR7A2 protein CTD PMID:22964423 hydrogen peroxide increases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:22964423 hypochlorous acid decreases expression ISO Akr7a5 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of AKR7A5 mRNA CTD PMID:19376150 indole-3-methanol increases expression EXP 6480464 indole-3-carbinol results in increased expression of AKR7A5 CTD PMID:9806166 indometacin multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Indomethacin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 inulin multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR7A5 mRNA CTD PMID:36331819 isatin affects reduction ISO Akr7a5 (Mus musculus) 6480464 Isatin affects the reduction of AKR7A5 protein CTD PMID:12604212 isatin increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of Isatin CTD PMID:10510318 ivermectin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR7A2 protein CTD PMID:32959892 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of AKR7A2 mRNA CTD PMID:19483382 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 menadione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione] and AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species] CTD PMID:22001351 menadione increases metabolic processing ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in increased metabolism of Vitamin K 3 CTD PMID:24590062 menadione decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to Vitamin K 3 CTD PMID:22001351 methamphetamine decreases methylation ISO Akr7a5 (Mus musculus) 6480464 Methamphetamine results in decreased methylation of AKR7A5 promoter CTD PMID:26307267 methylarsonic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 methylglyoxal decreases response to substance ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in decreased susceptibility to Pyruvaldehyde CTD PMID:24590062 methylglyoxal increases expression ISO AKR7A2 (Homo sapiens) 6480464 Pyruvaldehyde results in increased expression of AKR7A2 mRNA and Pyruvaldehyde results in increased expression of AKR7A2 protein CTD PMID:25451587 methylglyoxal decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to Pyruvaldehyde CTD PMID:22001351 and PMID:25451587 Muconic dialdehyde decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to muconaldehyde CTD PMID:22001351 Muconic dialdehyde decreases response to substance ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in decreased susceptibility to muconaldehyde analog CTD PMID:24590062 N-nitrosomorpholine decreases expression EXP 6480464 N-nitrosomorpholine results in decreased expression of AKR7A2 protein CTD PMID:19716841 NADP zwitterion multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 NADP(+) multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 naphthalenes multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 naringin multiple interactions ISO Akr7a5 (Mus musculus) 6480464 naringin inhibits the reaction [Acetaminophen results in decreased expression of AKR7A5 protein] CTD PMID:35166444 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of AKR7A2 mRNA CTD PMID:24136188 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 non-2-enal decreases response to substance ISO Akr7a5 (Mus musculus) 6480464 AKR7A5 protein results in decreased susceptibility to 2-nonenal CTD PMID:24590062 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 ozone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA more ... CTD PMID:32699268 and PMID:35430440 ozone multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of AKR7A5 mRNA CTD PMID:34911549 paracetamol increases expression ISO AKR7A2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of AKR7A2 mRNA CTD PMID:25704631 paracetamol multiple interactions ISO Akr7a5 (Mus musculus) 6480464 naringin inhibits the reaction [Acetaminophen results in decreased expression of AKR7A5 protein] CTD PMID:35166444 paracetamol decreases expression ISO Akr7a5 (Mus musculus) 6480464 Acetaminophen results in decreased expression of AKR7A5 protein CTD PMID:35166444 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of AKR7A2 mRNA CTD PMID:33387578 perfluorooctane-1-sulfonic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR7A5 mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression ISO AKR7A2 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of AKR7A2 protein CTD PMID:26879310 phenobarbital affects expression ISO AKR7A2 (Homo sapiens) 6480464 Phenobarbital affects the expression of AKR7A2 mRNA CTD PMID:19159669 phlorizin increases expression ISO Akr7a5 (Mus musculus) 6480464 Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 picoxystrobin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 picoxystrobin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 pirinixic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AKR7A2 mRNA CTD PMID:19710929 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of AKR7A2 mRNA CTD PMID:19483382 piroxicam decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Piroxicam results in decreased expression of AKR7A2 mRNA CTD PMID:21858171 Propiverine affects binding EXP 6480464 propiverine binds to AKR7A2 protein CTD PMID:29273565 pyrimidifen decreases expression ISO AKR7A2 (Homo sapiens) 6480464 pyrimidifen results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 quercetin multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Quercetin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA CTD PMID:16079270 reactive oxygen species multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species] CTD PMID:22001351 rotenone decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Rotenone results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 sodium arsenate multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AKR7A2 protein CTD PMID:29459688 sodium arsenite multiple interactions ISO Akr7a5 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 sodium fluoride decreases expression ISO Akr7a5 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of AKR7A2 protein CTD PMID:28918527 Soman decreases expression EXP 6480464 Soman results in decreased expression of AKR7A2 mRNA CTD PMID:19281266 succinic semialdehyde increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318 succinic semialdehyde affects reduction ISO Akr7a5 (Mus musculus) 6480464 succinic semialdehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 superoxide multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in increased chemical synthesis of Superoxides more ... CTD PMID:21910479 tartrazine multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:33819548 tebufenpyrad decreases expression ISO AKR7A2 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA] CTD PMID:31150632 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of AKR7A2 mRNA CTD PMID:19483382 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of AKR7A2 mRNA CTD PMID:34492290 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of AKR7A2 mRNA CTD PMID:33387578 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of AKR7A2 mRNA CTD PMID:30589522 Triptolide increases expression EXP 6480464 triptolide results in increased expression of AKR7A2 protein CTD PMID:32519852 umbelliferone increases expression ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin results in increased expression of AKR7A2 mRNA and 7-hydroxycoumarin results in increased expression of AKR7A2 protein CTD PMID:22964423 more ... umbelliferone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 valproic acid multiple interactions ISO Akr7a5 (Mus musculus) 6480464 Valproic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 vancomycin increases expression ISO Akr7a5 (Mus musculus) 6480464 Vancomycin results in increased expression of AKR7A5 mRNA CTD PMID:18930951 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of AKR7A2 mRNA CTD PMID:22570695