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Gene: Sfpq (splicing factor proline and glutamine rich) Rattus norvegicus
Symbol: Sfpq
Name: splicing factor proline and glutamine rich
RGD ID: 727923
Description: Predicted to have several functions, including E-box binding activity; histone deacetylase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including dendritic transport of messenger ribonucleoprotein complex; nucleic acid metabolic process; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription regulator complex; chromatin; and nuclear lumen. Orthologous to human SFPQ (splicing factor proline and glutamine rich); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: LOC252855; MGC112723; NonO/p54nrb homolog; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine-rich; splicing factor, proline- and glutamine-rich
Homo sapiens (human) : SFPQ (splicing factor proline and glutamine rich)  HGNC  Alliance
Mus musculus (house mouse) : Sfpq (splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfpq (splicing factor proline and glutamine rich)
Pan paniscus (bonobo/pygmy chimpanzee) : SFPQ (splicing factor proline and glutamine rich)
Canis lupus familiaris (dog) : SFPQ (splicing factor proline and glutamine rich)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfpq (splicing factor proline and glutamine rich)
Sus scrofa (pig) : SFPQ (splicing factor proline and glutamine rich)
Chlorocebus sabaeus (African green monkey) : SFPQ (splicing factor proline and glutamine rich)
Heterocephalus glaber (naked mole-rat) : Sfpq (splicing factor proline and glutamine rich)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05145,079,803 - 145,088,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5145,079,803 - 145,088,498 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05148,849,944 - 148,858,919 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45146,460,306 - 146,469,289 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15146,474,790 - 146,479,335 (+)NCBI
Celera5137,833,201 - 137,841,438 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sfpq
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727923
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.