Tnfrsf14 (TNF receptor superfamily member 14) - Rat Genome Database

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Gene: Tnfrsf14 (TNF receptor superfamily member 14) Rattus norvegicus
Analyze
Symbol: Tnfrsf14
Name: TNF receptor superfamily member 14
RGD ID: 1310115
Description: Predicted to enable cytokine binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including defense response to bacterium; negative regulation of adaptive immune memory response; and regulation of T cell activation. Predicted to act upstream of or within negative regulation of CD4-positive, alpha-beta T cell proliferation and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of myocardial infarction. Orthologous to human TNFRSF14 (TNF receptor superfamily member 14); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC366518; MGC108903; tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,768,413 - 170,776,749 (-)NCBIGRCr8
mRatBN7.25165,486,069 - 165,494,421 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5165,484,262 - 165,493,703 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,191,197 - 168,198,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,012,607 - 170,020,302 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,975,147 - 169,982,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05172,328,259 - 172,337,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5172,328,262 - 172,335,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,784,222 - 175,792,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,727,707 - 171,735,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15171,738,202 - 171,745,835 (-)NCBI
Celera5163,692,588 - 163,700,221 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,1,1-trichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (ISO)
diarsenic trioxide  (ISO)
diethyl maleate  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
exemestane  (ISO)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
irinotecan  (EXP)
lipopolysaccharide  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
sodium arsenate  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
XL147  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure. Dahl CP, etal., Eur J Heart Fail. 2008 Apr;10(4):352-9. Epub 2008 Mar 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases. Lee WH, etal., Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):2004-10.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10754304   PMID:11279055   PMID:15568026   PMID:18193050   PMID:21236258   PMID:22801499   PMID:27152329  


Genomics

Comparative Map Data
Tnfrsf14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,768,413 - 170,776,749 (-)NCBIGRCr8
mRatBN7.25165,486,069 - 165,494,421 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5165,484,262 - 165,493,703 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,191,197 - 168,198,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,012,607 - 170,020,302 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,975,147 - 169,982,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05172,328,259 - 172,337,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5172,328,262 - 172,335,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,784,222 - 175,792,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,727,707 - 171,735,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15171,738,202 - 171,745,835 (-)NCBI
Celera5163,692,588 - 163,700,221 (-)NCBICelera
Cytogenetic Map5q36NCBI
TNFRSF14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812,554,234 - 2,563,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12,555,639 - 2,565,382 (+)EnsemblGRCh38hg38GRCh38
GRCh3712,487,810 - 2,495,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612,479,150 - 2,486,613 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412,521,454 - 2,528,915NCBI
Celera190,732 - 98,195 (-)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef11,767,040 - 1,774,503 (+)NCBIHuRef
CHM1_112,474,873 - 2,482,336 (+)NCBICHM1_1
T2T-CHM13v2.011,997,007 - 2,005,473 (+)NCBIT2T-CHM13v2.0
Tnfrsf14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,002,944 - 155,013,077 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,006,390 - 155,013,020 (-)EnsemblGRCm39 Ensembl
GRCm384154,918,487 - 154,928,620 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4154,921,933 - 154,928,563 (-)EnsemblGRCm38mm10GRCm38
MGSCv374154,296,319 - 154,302,186 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364153,766,010 - 153,771,877 (-)NCBIMGSCv36mm8
Celera4157,193,781 - 157,199,645 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map485.81NCBI
Tnfrsf14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554868,670,182 - 8,684,677 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,684,004 - 225,692,010 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,344,543 - 224,352,496 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011,288,493 - 1,296,532 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112,427,421 - 2,435,615 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12,427,631 - 2,435,615 (+)Ensemblpanpan1.1panPan2
TNFRSF14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1557,386,190 - 57,416,864 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl557,411,529 - 57,416,512 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha557,425,462 - 57,430,262 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0557,611,566 - 57,621,030 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl557,614,515 - 57,621,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1557,607,109 - 57,611,909 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0557,499,417 - 57,504,217 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,889,145 - 57,893,945 (+)NCBIUU_Cfam_GSD_1.0
Tnfrsf14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505828,452,172 - 28,456,039 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367371,008,228 - 1,013,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120128,992,572 - 128,999,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20128,992,489 - 129,000,338 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605433,335,588 - 33,343,167 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfrsf14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248187,491,473 - 7,505,185 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnfrsf14
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:373
Count of miRNA genes:204
Interacting mature miRNAs:239
Transcripts:ENSRNOT00000018494
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat

Markers in Region
RH130715  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25165,486,118 - 165,486,270 (+)MAPPERmRatBN7.2
Rnor_6.05172,328,309 - 172,328,460NCBIRnor6.0
Rnor_5.05175,784,272 - 175,784,423UniSTSRnor5.0
RGSC_v3.45171,727,757 - 171,727,908UniSTSRGSC3.4
Celera5163,692,638 - 163,692,789UniSTS
RH 3.4 Map51155.5UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 109 91 90 59 25 59 6 218 97 89 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001015034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001837848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_354472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_354474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_354475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC134160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018494   ⟹   ENSRNOP00000018492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5165,486,064 - 165,493,703 (-)Ensembl
Rnor_6.0 Ensembl5172,328,262 - 172,335,892 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103957   ⟹   ENSRNOP00000096903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5165,484,262 - 165,493,703 (-)Ensembl
RefSeq Acc Id: NM_001015034   ⟹   NP_001015034
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,046 (-)NCBI
mRatBN7.25165,486,069 - 165,493,703 (-)NCBI
Rnor_6.05172,328,259 - 172,335,892 (-)NCBI
Rnor_5.05175,784,222 - 175,792,597 (-)NCBI
RGSC_v3.45171,727,707 - 171,735,340 (-)RGD
Celera5163,692,588 - 163,700,221 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239586   ⟹   XP_006239648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,665 (-)NCBI
mRatBN7.25165,486,069 - 165,494,324 (-)NCBI
Rnor_6.05172,328,259 - 172,337,219 (-)NCBI
Rnor_5.05175,784,222 - 175,792,597 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239587   ⟹   XP_006239649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,668 (-)NCBI
mRatBN7.25165,486,069 - 165,494,330 (-)NCBI
Rnor_6.05172,328,259 - 172,337,220 (-)NCBI
Rnor_5.05175,784,222 - 175,792,597 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110507   ⟹   XP_038966435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,667 (-)NCBI
mRatBN7.25165,486,069 - 165,494,328 (-)NCBI
RefSeq Acc Id: XM_039110508   ⟹   XP_038966436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,458 (-)NCBI
mRatBN7.25165,486,069 - 165,494,110 (-)NCBI
RefSeq Acc Id: XM_039110509   ⟹   XP_038966437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,668 (-)NCBI
mRatBN7.25165,486,069 - 165,494,330 (-)NCBI
RefSeq Acc Id: XM_039110510   ⟹   XP_038966438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,744 (-)NCBI
mRatBN7.25165,486,069 - 165,494,421 (-)NCBI
RefSeq Acc Id: XM_039110511   ⟹   XP_038966439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,031 (-)NCBI
mRatBN7.25165,486,069 - 165,493,687 (-)NCBI
RefSeq Acc Id: XM_063288144   ⟹   XP_063144214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,770,207 - 170,776,663 (-)NCBI
RefSeq Acc Id: XM_063288145   ⟹   XP_063144215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,749 (-)NCBI
RefSeq Acc Id: XM_063288146   ⟹   XP_063144216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,458 (-)NCBI
RefSeq Acc Id: XM_063288147   ⟹   XP_063144217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,729 (-)NCBI
RefSeq Acc Id: XM_063288148   ⟹   XP_063144218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,768,413 - 170,776,732 (-)NCBI
RefSeq Acc Id: NP_001015034   ⟸   NM_001015034
- Peptide Label: precursor
- UniProtKB: Q5BK53 (UniProtKB/TrEMBL),   F7F4X8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239649   ⟸   XM_006239587
- Peptide Label: isoform X5
- UniProtKB: F7F4X8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239648   ⟸   XM_006239586
- Peptide Label: isoform X4
- UniProtKB: A6IUM8 (UniProtKB/TrEMBL),   F7F4X8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018492   ⟸   ENSRNOT00000018494
RefSeq Acc Id: XP_038966438   ⟸   XM_039110510
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038966437   ⟸   XM_039110509
- Peptide Label: isoform X2
- UniProtKB: F7F4X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966435   ⟸   XM_039110507
- Peptide Label: isoform X1
- UniProtKB: F7F4X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966436   ⟸   XM_039110508
- Peptide Label: isoform X1
- UniProtKB: F7F4X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966439   ⟸   XM_039110511
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000096903   ⟸   ENSRNOT00000103957
RefSeq Acc Id: XP_063144215   ⟸   XM_063288145
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063144218   ⟸   XM_063288148
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063144217   ⟸   XM_063288147
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063144216   ⟸   XM_063288146
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063144214   ⟸   XM_063288144
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ATG2 (UniProtKB/TrEMBL)
Protein Domains
TNFR-Cys

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK53-F1-model_v2 AlphaFold Q5BK53 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310115 AgrOrtholog
BioCyc Gene G2FUF-38944 BioCyc
Ensembl Genes ENSRNOG00000013820 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018494.6 UniProtKB/TrEMBL
  ENSRNOT00000103957.1 UniProtKB/TrEMBL
Gene3D-CATH Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7380378 IMAGE-MGC_LOAD
InterPro TNFR_14 UniProtKB/TrEMBL
  TNFR_Cys_rich_reg UniProtKB/TrEMBL
  TNFRSF14/UL144_N UniProtKB/TrEMBL
KEGG Report rno:366518 UniProtKB/TrEMBL
MGC_CLONE MGC:108903 IMAGE-MGC_LOAD
NCBI Gene 366518 ENTREZGENE
PANTHER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 UniProtKB/TrEMBL
Pfam TNFR_c6 UniProtKB/TrEMBL
PharmGKB TNFRSF14 RGD
PhenoGen Tnfrsf14 PhenoGen
PRINTS TNFACTORR14 UniProtKB/TrEMBL
PROSITE TNFR_NGFR_1 UniProtKB/TrEMBL
  TNFR_NGFR_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013820 RatGTEx
SMART TNFR UniProtKB/TrEMBL
Superfamily-SCOP TNF receptor-like UniProtKB/TrEMBL
UniProt A0A8I6ATG2 ENTREZGENE, UniProtKB/TrEMBL
  A6IUM8 ENTREZGENE, UniProtKB/TrEMBL
  F7F4X8 ENTREZGENE, UniProtKB/TrEMBL
  Q5BK53 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-05 Tnfrsf14  TNF receptor superfamily member 14  Tnfrsf14  tumor necrosis factor receptor superfamily, member 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-18 Tnfrsf14  tumor necrosis factor receptor superfamily, member 14  Tnfrsf14  tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tnfrsf14  tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)  Tnfrsf14_predicted  tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tnfrsf14_predicted  tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (predicted)      Symbol and Name status set to approved 70820 APPROVED