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Gene: Mmachc (metabolism of cobalamin associated C) Rattus norvegicus
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Symbol: Mmachc
Name: metabolism of cobalamin associated C
Description: Predicted to have several functions, including anion binding activity; cyanocobalamin reductase (cyanide-eliminating) activity; and protein homodimerization activity. Predicted to be involved in several processes, including cobalamin biosynthetic process; demethylation; and glutathione metabolic process. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human MMACHC (metabolism of cobalamin associated C); INTERACTS WITH (RS)-amphetamine; 2,6-dinitrotoluene; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC313520; methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; RGD1310806; similar to RIKEN cDNA 1810037K07
Orthologs:
Homo sapiens (human) : MMACHC (metabolism of cobalamin associated C)  HGNC  Alliance
Mus musculus (house mouse) : Mmachc (methylmalonic aciduria cblC type, with homocystinuria)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmachc (metabolism of cobalamin associated C)
Pan paniscus (bonobo/pygmy chimpanzee) : MMACHC (metabolism of cobalamin associated C)
Canis lupus familiaris (dog) : MMACHC (metabolism of cobalamin associated C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmachc (metabolism of cobalamin associated C)
Sus scrofa (pig) : MMACHC (metabolism of cobalamin associated C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05135,555,587 - 135,561,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05139,351,762 - 139,357,898 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,995,231 - 137,001,367 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,001,103 - 137,006,588 (-)NCBI
Celera5128,693,619 - 128,699,745 (-)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mmachc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310806
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.