Gene: Mknk1 (MAP kinase-interacting serine/threonine kinase 1) Rattus norvegicus
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Symbol: Mknk1
Name: MAP kinase-interacting serine/threonine kinase 1
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity; ATP binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation; regulation of translational initiation; extrinsic apoptotic signaling pathway in absence of ligand (ortholog); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; cyclooxygenase mediated pathway of arachidonic acid metabolism; p38 MAPK signaling pathway; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MGC112775; mnk1; similar to map kinase interacting kinase
Orthologs:
Homo sapiens (human) : MKNK1 (MAP kinase interacting serine/threonine kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mknk1 (MAP kinase-interacting serine/threonine kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mknk1 (MAP kinase interacting serine/threonine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MKNK1 (MAP kinase interacting serine/threonine kinase 1)
Canis lupus familiaris (dog) : MKNK1 (MAP kinase interacting serine/threonine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mknk1 (MAP kinase interacting serine/threonine kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05134,691,852 - 134,730,887 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05138,476,301 - 138,514,361 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,100,236 - 136,141,344 (+)NCBIRGSC3.4rn4RGSC3.4
Celera5127,849,685 - 127,888,824 (+)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mknk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559603
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2018-11-20
Status: ACTIVE