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Gene: Kif1b (kinesin family member 1B) Rattus norvegicus
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Symbol: Kif1b
Name: kinesin family member 1B
Description: Exhibits ATP-dependent microtubule motor activity; kinase binding activity; and scaffold protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cytoskeleton-dependent intracellular transport; and response to rotenone. Localizes to the cytoplasm; membrane; and neuron projection. Biomarker of amyotrophic lateral sclerosis and synucleinopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; endocrine gland cancer (multiple); multiple sclerosis; neuroblastoma; and pheochromocytoma. Orthologous to human KIF1B (kinesin family member 1B); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: kinesin-family protein KIF1Bbeta3; kinesin-like protein KIF1B
Orthologs:
Homo sapiens (human) : KIF1B (kinesin family member 1B)  HGNC  Alliance
Mus musculus (house mouse) : Kif1b (kinesin family member 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kif1b (kinesin family member 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : KIF1B (kinesin family member 1B)
Canis lupus familiaris (dog) : KIF1B (kinesin family member 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kif1b (kinesin family member 1B)
Sus scrofa (pig) : KIF1B (kinesin family member 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05165,994,803 - 166,133,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05169,643,325 - 169,780,881 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,250,225 - 166,381,782 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15166,260,412 - 166,391,970 (-)NCBI
Celera5157,882,642 - 158,013,175 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kif1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621520
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.