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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | increases expression | ISO | RGD:733254 | 6480464 | vinylidene chloride results in increased expression of FGR mRNA | CTD | PMID:26682919 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of FGR mRNA | CTD | PMID:25380136 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:733254 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGR mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:733253 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of FGR mRNA | CTD | PMID:20404318 | 17beta-estradiol | increases expression | ISO | RGD:733253 | 6480464 | Estradiol results in increased expression of FGR mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:733254 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGR mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGR mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGR mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733254 | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGR mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of FGR mRNA] | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGR mRNA | CTD | PMID:21215274 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of FGR mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:733253 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FGR mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of FGR mRNA | CTD | PMID:25380136 | 4-hydroxynon-2-enal | decreases expression | ISO | RGD:733254 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of FGR mRNA | CTD | PMID:19191707 | 4-hydroxynon-2-enal | increases expression | ISO | RGD:733254 | 6480464 | 4-hydroxy-2-nonenal results in increased expression of FGR mRNA | CTD | PMID:19191707 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of FGR mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FGR mRNA | CTD | PMID:31881176 | acetylsalicylic acid | decreases expression | ISO | RGD:733253 | 6480464 | Aspirin results in decreased expression of FGR mRNA | CTD | PMID:15928584 | aflatoxin B1 | increases methylation | ISO | RGD:733253 | 6480464 | Aflatoxin B1 results in increased methylation of FGR intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | RGD:733253 | 6480464 | aflatoxin B2 results in increased methylation of FGR intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RGD:733253 | 6480464 | Tretinoin results in increased expression of FGR mRNA | CTD | PMID:15498508 more ... | all-trans-retinoic acid | multiple interactions | ISO | RGD:733253 | 6480464 | KAT2B protein promotes the reaction [Tretinoin results in increased expression of FGR mRNA] | CTD | PMID:28053092 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FGR mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | RGD:733253 | 6480464 | Antirheumatic Agents results in decreased expression of FGR mRNA | CTD | PMID:24449571 | arsenous acid | increases expression | ISO | RGD:733253 | 6480464 | Arsenic Trioxide results in increased expression of FGR mRNA | CTD | PMID:15761015 | benzalkonium chloride | increases expression | ISO | RGD:733254 | 6480464 | Benzalkonium Compounds results in increased expression of FGR mRNA | CTD | PMID:30171875 | benzo[a]pyrene | decreases expression | ISO | RGD:733254 | 6480464 | Benzo(a)pyrene results in decreased expression of FGR mRNA | CTD | PMID:21569818 | benzo[a]pyrene | affects methylation | ISO | RGD:733253 | 6480464 | Benzo(a)pyrene affects the methylation of FGR 5' UTR, Benzo(a)pyrene affects the methylation of FGR promoter | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:733254 | 6480464 | Mustard Gas results in increased expression of FGR mRNA | CTD | PMID:15674843 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of FGR mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:733254 | 6480464 | bisphenol A results in decreased expression of FGR mRNA | CTD | PMID:34585602 | bisphenol A | multiple interactions | ISO | RGD:733253 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FGR mRNA | CTD | PMID:28628672 | bosutinib | decreases activity | EXP | | 6480464 | bosutinib results in decreased activity of FGR protein | CTD | PMID:17114238 | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of FGR mRNA | CTD | PMID:32479839 | buta-1,3-diene | decreases expression | ISO | RGD:733254 | 6480464 | 1, 3-butadiene results in decreased expression of FGR mRNA | CTD | PMID:29038090 | butan-1-ol | multiple interactions | ISO | RGD:733253 | 6480464 | 1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of FGR protein] | CTD | PMID:11078731 | cadmium dichloride | increases expression | ISO | RGD:733253 | 6480464 | Cadmium Chloride results in increased expression of FGR mRNA | CTD | PMID:25596134 | carbon nanotube | increases expression | ISO | RGD:733254 | 6480464 | Nanotubes more ... | CTD | PMID:25554681, PMID:25620056 | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of FGR mRNA | CTD | PMID:23125180 | chloroprene | decreases expression | ISO | RGD:733254 | 6480464 | Chloroprene results in decreased expression of FGR mRNA | CTD | PMID:23125180 | chlorpromazine | decreases expression | EXP | | 6480464 | Chlorpromazine results in decreased expression of FGR mRNA | CTD | PMID:25596134 | cisplatin | increases expression | ISO | RGD:733253 | 6480464 | Cisplatin results in increased expression of FGR mRNA | CTD | PMID:27594783 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of FGR mRNA | CTD | PMID:27523638 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of FGR mRNA | CTD | PMID:25596134 | dexamethasone | multiple interactions | ISO | RGD:733253 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FGR mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | RGD:733253 | 6480464 | Arsenic Trioxide results in increased expression of FGR mRNA | CTD | PMID:15761015 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of FGR mRNA | CTD | PMID:18636392 | diethyl maleate | decreases expression | EXP | | 6480464 | diethyl maleate results in decreased expression of FGR mRNA | CTD | PMID:21161181 | diethylstilbestrol | increases expression | ISO | RGD:733253 | 6480464 | Diethylstilbestrol results in increased expression of FGR mRNA | CTD | PMID:15766595 | dimethylarsinic acid | multiple interactions | ISO | RGD:733254 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FGR mRNA | CTD | PMID:34876320 | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of FGR mRNA | CTD | PMID:33729688 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of FGR mRNA | CTD | PMID:29391264 | fenofibrate | affects expression | EXP | | 6480464 | Fenofibrate affects the expression of FGR mRNA | CTD | PMID:25596134 | genistein | increases expression | ISO | RGD:733254 | 6480464 | Genistein results in increased expression of FGR mRNA | CTD | PMID:32186404 | hypochlorous acid | decreases expression | ISO | RGD:733254 | 6480464 | Hypochlorous Acid results in decreased expression of FGR mRNA | CTD | PMID:19376150 | indometacin | multiple interactions | ISO | RGD:733253 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FGR mRNA | CTD | PMID:28628672 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of FGR mRNA | CTD | PMID:24136188 | lipopolysaccharide | increases expression | ISO | RGD:733254 | 6480464 | Lipopolysaccharides results in increased expression of FGR mRNA | CTD | PMID:12057914 | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of FGR mRNA | CTD | PMID:25596134 | methylarsonic acid | multiple interactions | ISO | RGD:733254 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FGR mRNA | CTD | PMID:34876320 | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of FGR mRNA | CTD | PMID:21515302 | N-formyl-L-methionyl-L-leucyl-L-phenylalanine | multiple interactions | ISO | RGD:733253 | 6480464 | 1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of FGR protein] | CTD | PMID:11078731 | N-formyl-L-methionyl-L-leucyl-L-phenylalanine | increases phosphorylation | ISO | RGD:733253 | 6480464 | N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of FGR protein | CTD | PMID:25980585 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of FGR mRNA | CTD | PMID:25380136 | nickel atom | decreases expression | ISO | RGD:733253 | 6480464 | Nickel results in decreased expression of FGR mRNA | CTD | PMID:23195993 | nickel atom | increases expression | ISO | RGD:733253 | 6480464 | Nickel results in increased expression of FGR mRNA | CTD | PMID:25583101 | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of FGR mRNA | CTD | PMID:22546817 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of FGR mRNA | CTD | PMID:18636392 | paracetamol | increases expression | ISO | RGD:733253 | 6480464 | Acetaminophen results in increased expression of FGR mRNA | CTD | PMID:26690555 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FGR mRNA | CTD | PMID:33387578 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of FGR mRNA | CTD | PMID:28511854 | phosphatidic acid | increases activity | ISO | RGD:733253 | 6480464 | Phosphatidic Acids results in increased activity of FGR protein | CTD | PMID:11078731 | ponatinib | decreases activity | ISO | RGD:733253 | 6480464 | ponatinib results in decreased activity of FGR protein | CTD | PMID:19878872 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of FGR mRNA | CTD | PMID:25905778 | SB 431542 | increases expression | ISO | RGD:733253 | 6480464 | 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of FGR protein | CTD | PMID:25670856 | silicon dioxide | increases expression | ISO | RGD:733253 | 6480464 | Silicon Dioxide analog results in increased expression of FGR mRNA | CTD | PMID:23806026, PMID:25895662 | sodium arsenate | multiple interactions | ISO | RGD:733254 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FGR mRNA | CTD | PMID:34876320 | sodium arsenite | decreases expression | ISO | RGD:733253 | 6480464 | sodium arsenite results in decreased expression of FGR mRNA | CTD | PMID:29301061 | sodium arsenite | multiple interactions | ISO | RGD:733254 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FGR mRNA | CTD | PMID:34876320 | sodium fluoride | increases expression | ISO | RGD:733254 | 6480464 | Sodium Fluoride results in increased expression of FGR mRNA | CTD | PMID:27862939 | tamibarotene | increases expression | ISO | RGD:733253 | 6480464 | tamibarotene results in increased expression of FGR mRNA | CTD | PMID:15498508 | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of FGR mRNA | CTD | PMID:21515302 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FGR mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | RGD:733254 | 6480464 | titanium dioxide results in increased expression of FGR mRNA | CTD | PMID:23557971 | triptonide | increases expression | ISO | RGD:733254 | 6480464 | triptonide results in increased expression of FGR mRNA | CTD | PMID:33045310 | troglitazone | increases expression | ISO | RGD:733254 | 6480464 | troglitazone results in increased expression of FGR mRNA | CTD | PMID:28973697 | tungsten | decreases expression | ISO | RGD:733254 | 6480464 | Tungsten results in decreased expression of FGR mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | RGD:733253 | 6480464 | Valproic Acid results in increased methylation of FGR gene | CTD | PMID:29154799 | vincristine | decreases expression | ISO | RGD:733253 | 6480464 | Vincristine results in decreased expression of FGR mRNA | CTD | PMID:23649840 | |