Fgr (FGR proto-oncogene, Src family tyrosine kinase)

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Gene: Fgr (FGR proto-oncogene, Src family tyrosine kinase) Rattus norvegicus

Analyze

Symbol:

Fgr

Name:

FGR proto-oncogene, Src family tyrosine kinase

RGD ID:

621319

Description:

Exhibits protein tyrosine kinase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of secretion by cell; and regulation of kinase activity. Localizes to cytosol and plasma membrane. Predicted to colocalize with actin cytoskeleton and ruffle membrane. Orthologous to human FGR (FGR proto-oncogene, Src family tyrosine kinase); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

feline Gardner-Rasheed sarcoma viral oncogene; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; p55-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase Fgr; tyrosine-protein kinase Fgr

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	152,129,494 - 152,157,096 (-)	NCBI
Celera	5	143,612,003 - 143,639,441 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI
RH 3.4 Map	5	977.8	RGD

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzalkonium chloride (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bosutinib (EXP)

bromobenzene (EXP)

buta-1,3-diene (ISO)

butan-1-ol (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroprene (EXP,ISO)

chlorpromazine (EXP)

cisplatin (ISO)

cyclosporin A (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dichlorine (EXP)

diethyl maleate (EXP)

diethylstilbestrol (ISO)

endosulfan (EXP)

fenofibrate (EXP)

genistein (ISO)

hypochlorous acid (ISO)

indometacin (ISO)

leflunomide (EXP)

lipopolysaccharide (ISO)

metformin (EXP)

N-formyl-L-methionyl-L-leucyl-L-phenylalanine (ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

nickel dichloride (EXP)

ozone (EXP)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

phosphatidic acid (ISO)

ponatinib (ISO)

resveratrol (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamibarotene (ISO)

Tesaglitazar (EXP)

titanium dioxide (ISO)

troglitazone (ISO)

tungsten (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

bone mineralization (ISO)

cell differentiation (IBA)

defense response to Gram-positive bacterium (ISO,ISS)

innate immune response (IBA)

integrin-mediated signaling pathway (IBA,ISO,ISS)

negative regulation of natural killer cell activation (ISO)

peptidyl-tyrosine autophosphorylation (IBA)

peptidyl-tyrosine phosphorylation (ISO,ISS)

positive regulation of cell migration (ISO,ISS)

positive regulation of cytokine production (ISO,ISS)

positive regulation of mast cell degranulation (ISO,ISS)

positive regulation of phosphatidylinositol 3-kinase activity (ISO)

positive regulation of phosphatidylinositol 3-kinase signaling (ISO)

protein autophosphorylation (ISO)

regulation of cell population proliferation (IBA)

regulation of cell shape (ISO,ISS)

regulation of innate immune response (ISO,ISS)

regulation of phagocytosis (ISO,ISS)

regulation of protein kinase activity (ISO,ISS)

skeletal system morphogenesis (ISO)

transmembrane receptor protein tyrosine kinase signaling pathway (IBA)

Cellular Component

actin cytoskeleton (ISO,ISS)

aggresome (IEA,ISO)

cytoskeleton (ISO)

cytosol (IDA)

extrinsic component of cytoplasmic side of plasma membrane (IBA)

mitochondrial inner membrane (IEA)

mitochondrial intermembrane space (IEA)

plasma membrane (IDA,ISO)

ruffle membrane (ISO,ISS)

Molecular Function

ATP binding (IEA)

Fc-gamma receptor I complex binding (ISO)

immunoglobulin receptor binding (ISO,ISS)

non-membrane spanning protein tyrosine kinase activity (IBA,ISO)

phosphotyrosine residue binding (ISO,ISS)

protein binding (IPI,ISO)

protein kinase binding (ISO,ISS)

protein tyrosine kinase activity (IDA,ISO)

signaling receptor binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

chemokine mediated signaling pathway (IEA)

eicosanoid signaling pathway (ISO)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

glypican signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

References

References - curated


1.	Brunati AM, etal., Eur J Biochem. 1995 Apr 1;229(1):164-70.
2.	Choi WS, etal., Mol Cell Biol 2004 Aug;24(16):6980-92.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA data from the GO Consortium
5.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6.	MGD data from the GO Consortium
7.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	Pipeline to import KEGG annotations from KEGG into RGD
9.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10.	RGD automated data pipeline
11.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	RGD automated import pipeline for gene-chemical interactions
13.	RGD comprehensive gene curation
14.	Stenberg PE, etal., Blood. 1997 Apr 1;89(7):2384-93.
15.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:2181286	PMID:7519620	PMID:8125254	PMID:8327512	PMID:8402898	PMID:8603737	PMID:10739672	PMID:10861086	PMID:11672534	PMID:11744621	PMID:15561106	PMID:16439675
PMID:16921024	PMID:16964445	PMID:20458337	PMID:20624904	PMID:21746961	PMID:22871113	PMID:30352950

Genomics

Comparative Map Data

Fgr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	152,129,494 - 152,157,096 (-)	NCBI
Celera	5	143,612,003 - 143,639,441 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI
RH 3.4 Map	5	977.8	RGD

FGR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	27,612,064 - 27,635,185 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	27,612,064 - 27,635,561 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	27,938,800 - 27,961,727 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	27,811,387 - 27,834,314 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	27,622,952 - 27,634,715	NCBI
Celera	1	26,334,465 - 26,357,390 (-)	NCBI
Cytogenetic Map	1	p35.3	NCBI
HuRef	1	26,195,016 - 26,217,930 (-)	NCBI		HuRef
CHM1_1	1	28,054,060 - 28,076,993 (-)	NCBI		CHM1_1

Fgr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	132,701,406 - 132,729,204 (+)	NCBI	GRCm39		mm39
GRCm38	4	132,974,095 - 133,001,893 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	132,974,095 - 133,001,910 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	132,530,010 - 132,557,808 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	132,246,204 - 132,273,882 (+)	NCBI			mm8
Celera	4	131,136,566 - 131,164,622 (+)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.11	NCBI

Fgr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	6,841,802 - 6,863,542 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	6,840,274 - 6,863,460 (-)	NCBI	ChiLan1.0	ChiLan1.0

FGR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	27,918,758 - 27,941,678 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	27,918,758 - 27,941,678 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	26,872,781 - 26,895,751 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

FGR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	2	72,680,675 - 72,690,251 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	2	72,678,858 - 72,692,417 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Fgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936474	11,897,998 - 11,919,153 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FGR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	84,809,542 - 84,830,361 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	84,809,534 - 84,830,401 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	78,326,176 - 78,358,345 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FGR
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	20	105,165,043 - 105,179,067 (+)	Ensembl
ChlSab1.1	20	105,155,223 - 105,178,813 (+)	NCBI

Fgr
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624764	11,482,719 - 11,513,215 (-)	NCBI

Position Markers

D5Got83

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	151,187,978 - 151,188,171	NCBI	Rnor6.0
Rnor_5.0	5	154,854,649 - 154,854,842	UniSTS	Rnor5.0
RGSC_v3.4	5	152,131,030 - 152,131,224	RGD	RGSC3.4
RGSC_v3.4	5	152,131,031 - 152,131,224	UniSTS	RGSC3.4
RGSC_v3.1	5	152,141,070 - 152,141,263	RGD
Celera	5	143,627,672 - 143,627,865	UniSTS
Cytogenetic Map	5	q36	UniSTS
RH 3.4 Map	5	989.2	UniSTS
RH 3.4 Map	5	989.2	RGD

RH142441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	151,199,220 - 151,199,369	NCBI	Rnor6.0
Rnor_5.0	5	154,865,891 - 154,866,040	UniSTS	Rnor5.0
RGSC_v3.4	5	152,119,832 - 152,119,981	UniSTS	RGSC3.4
Celera	5	143,638,915 - 143,639,064	UniSTS
Cytogenetic Map	5	q36	UniSTS
RH 3.4 Map	5	977.8	UniSTS

RH141155

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	5	151,199,162 - 151,199,352	NCBI	Rnor6.0
Rnor_5.0	5	154,865,833 - 154,866,023	UniSTS	Rnor5.0
RGSC_v3.4	5	152,119,849 - 152,120,039	UniSTS	RGSC3.4
Celera	5	143,638,857 - 143,639,047	UniSTS
Cytogenetic Map	5	q36	UniSTS
RH 3.4 Map	5	977.8	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	149568588	167739697	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	149832180	164807402	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	142309061	173707219	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	134502140	157212422	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132551937	173707219	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149029982	173687766	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114140832	159140832	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	142307322	173707219	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	100723739	153577831	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	136354114	173707219	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138154677	172402610	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	84963058	173504662	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	128687766	173687766	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133943857	173707219	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114140832	159140832	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133943857	173707219	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	125455818	157225114	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	134197905	173707219	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	47745646	167946134	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	107119214	152119214	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	150340838	164298744	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	71552569	157225114	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111278451	156278451	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112279412	157279412	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40777918	154732375	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	102945579	154732228	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	150360936	167946134	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	61612600	168109659	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116767924	161767924	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136640731	173707219	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	134712342	173707219	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116767924	161767924	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116767924	161767924	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116767924	161767924	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	134712342	173707219	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112279412	157279412	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112279412	157279412	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112279412	157279412	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112279412	157279412	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	131077716	173707219	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	331
Count of miRNA genes:	195
Interacting mature miRNAs:	225
Transcripts:	ENSRNOT00000013778
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2				11						1	11
Low	1	27	57	41	8	41	6	9	31	33	39		6
Below cutoff		16					2	2	43	2	1		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07050102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01040094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC062025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X57018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013778 ⟹ ENSRNOP00000013779

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	151,172,206 - 151,199,745 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085674 ⟹ ENSRNOP00000075272

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	151,181,559 - 151,199,500 (+)	Ensembl

RefSeq Acc Id:

NM_024145 ⟹ NP_077059

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,206 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI
RGSC_v3.4	5	152,119,455 - 152,147,057 (-)	RGD
Celera	5	143,612,003 - 143,639,441 (+)	RGD

Sequence:

show sequence

GGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAAAATTAGGGTTGGCTCGC
CCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCGGCCAAACCAGGAGGAGG
CTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAAGGAAGATTTAGAGGTTT
CCGGCACCCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCT
GTGGGCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGG
ATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTAC
TCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAAC
ATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGA
CAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGA
CTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCT
CCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGA
GGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAA
AGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTAC
AAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGC
AGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACCGCACCCTG
TATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCC
ATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACT
GTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGA
GGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCA
GAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGG
ATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGG
CATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTG
GGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGACGATGAGT
ACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGG
CAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAG
GGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACC
ACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCT
GGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCC
ACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAG
ACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACC
CTGTGGAATCCTAGCACGTCAGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAA
TGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCC
ATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAG
TTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCG
TTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTT
CTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCACTCCAGCCCAGAC
CCTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCT
GCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCAT
TGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGA
TCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239079 ⟹ XP_006239141

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,181,962 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

AGAACAGAGCTGCTGGGGAAAGTTTGGCTACTTCCCAGATCTCTTCAAGAGACTATAGTGGCCC
CAGCTTCTCCCTAACCCTGGTCTGTAGGAGACTGTCACTTTCATCCTGGCACAAGAGGTTTCCG
GCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCTGTGG
GCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGGATGT
TGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTACTCAA
GGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAACATAA
GAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGACAGG
GGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGACTGG
TGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCTCCCG
TGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGAGGCA
GCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAAAGGT
GCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTACAAGA
TCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGCAGGA
CCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACGGCACCCTGTATG
GTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCCATAG
CACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACTGTAG
CACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGAGGAG
GCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCAGAGG
AACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGGATCG
AAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGGCATG
GCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTGGGGG
AACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGATGATGAGTACAA
CCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGGCAGA
TTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAGGGCA
GAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACCACAT
GCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCTGGAT
CCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCCACAG
AACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAGACTA
TGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACCCTGT
GGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAATGGA
GACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCCATGC
CCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAGTTCA
TCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCGTTAG
TCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTTCTCT
TCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCAGCCCAGACCTTA
AGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCTGCTT
GATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCATTGAA
GGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239080 ⟹ XP_006239142

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTTTCCG
GCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGACCCAGGAGTAGGGGCCTGTGG
GCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACCCAAGGAGGATGT
TGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCTGACCCTACTCAA
GGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATGTTGGCAACATAA
GAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGAGGCCAGGACAGG
GGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACGGAGTATGACTGG
TGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACTATGTGGCTCCCG
TGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGATGCAGAGAGGCA
GCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAGACCACCAAAGGT
GCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAAAGCATTACAAGA
TCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGAATCCGTGCAGGA
CCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACGGCACCCTGTATG
GTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACCGTAACTCCATAG
CACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCACGTGGAACTGTAG
CACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCCTTCCTGGAGGAG
GCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGGTGGTGTCAGAGG
AACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTTCCTAAAGGATCG
AAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTAGCAGAGGGCATG
GCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACATCCTGGTGGGGG
AACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGATGATGAGTACAA
CCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCTCTCTTTGGCAGA
TTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGATCACCAAGGGCA
GAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCACGGCTACCACAT
GCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACCTGGCGTCTGGAT
CCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATTTCACCTCCACAG
AACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGACCCTCTGAGACTA
TGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGACTTGGAACCCTGT
GGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAGGGTGCAAATGGA
GACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCTTCCCACCCATGC
CCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGATGCTCAGAGTTCA
TCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCTACGTACCGTTAG
TCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAATTGTATTTCTCT
TCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCAGCCCAGACCTTA
AGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGGACGTCTCTGCTT
GATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAGAGAGCCATTGAA
GGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239081 ⟹ XP_006239143

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCG
GCCAAACCAGGAGGAGGCTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAA
GGAAGATTTAGAGGTTTCCGGCACCCCCCCCCGCCCCCAGGGACCATGCATCAGTCCTACTGAC
CCAGGAGTAGGGGCCTGTGGGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCT
GCACCCAAGGAGGATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATT
ACCCTGACCCTACTCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCT
TAATGTTGGCAACATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGAC
TATGAGGCCAGGACAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACA
ATACGGAGTATGACTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAG
CAACTATGTGGCTCCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGA
AAGGATGCAGAGAGGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAA
GCGAGACCACCAAAGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCA
CATAAAGCATTACAAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAG
TTCGAATCCGTGCAGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGC
TCACGGCACCCTGTATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGAT
CGACCGTAACTCCATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTG
GGCACGTGGAACTGTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGA
AGGCCTTCCTGGAGGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTA
CGCGGTGGTGTCAGAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTG
GATTTCCTAAAGGATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCC
AGGTAGCAGAGGGCATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGC
CAACATCCTGGTGGGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATA
GTGGATGATGAGTACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGG
CTGCTCTCTTTGGCAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGA
ACTGATCACCAAGGGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTA
GAGCACGGCTACCACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGC
AGACCTGGCGTCTGGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGA
CTATTTCACCTCCACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCA
GTGACCCTCTGAGACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCC
GAGACTTGGAACCCTGTGGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTA
TAGAGGGTGCAAATGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCT
TCCCTTCCCACCCATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAA
TGGATGCTCAGAGTTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGG
CTCCTACGTACCGTTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTA
TAAAATTGTATTTCTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCG
CTCCAGCCCAGACCTTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGC
AGGGGACGTCTCTGCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGA
AGGAGAGAGCCATTGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAA
CGAACAGTGATGATCGA

hide sequence

RefSeq Acc Id:

XM_006239082 ⟹ XP_006239144

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,189 - 151,199,746 (+)	NCBI
Rnor_5.0	5	154,839,086 - 154,866,424 (+)	NCBI

Sequence:

show sequence

CCCAGAGTAGGTAGTAGGGACAGGGGCGGGTAGCACTTCACTTTCCCCTCACATCGTTCCTGAA
AATTAGGGTTGGCTCGCCCCAGATCGGGTCACCAGCAGCTGGCTCCCTTGAGACCAGGTAGGCG
GCCAAACCAGGAGGAGGCTGACCCGGCAGGTGTCGCCCCGCCCCTGTCCGTCCTCGCCCTGGAA
GGAAGATTTAGAGCAGGACACCTGGAATGGGCTGTGTGTTCTGCAAGAAGTTAGAGCCTGCACC
CAAGGAGGATGTTGGCCTGGAAGGGGACTTCCGGAGCCAAGGCGCTGAAGAACGCTATTACCCT
GACCCTACTCAAGGCCGGTCTTCGTCCATCTCGCCTCAGCCCATCAGCCCTGCTTTCCTTAATG
TTGGCAACATAAGAAGCGTCTCTGGGACGGGAGTGACCATATTCGTCGCCCTGTATGACTATGA
GGCCAGGACAGGGGATGACCTCACCTTCACCAAAGGCGAGAAGTTCCACATCCTGAACAATACG
GAGTATGACTGGTGGGAGGCTAGGTCCCTGAGCTCCGGACGCACGGGCTATGTTCCCAGCAACT
ATGTGGCTCCCGTGGATTCCATCCAGGCTGAAGAGTGGTACTTCGGAAAGATCAGCAGAAAGGA
TGCAGAGAGGCAGCTTCTCTCCGATGGCAACCCTCAAGGGGCCTTTCTCATTCGGGAAAGCGAG
ACCACCAAAGGTGCCTACTCCCTGTCCATCCGTGACTGGGACCAGAACAGAGGCGACCACATAA
AGCATTACAAGATCCGAAAGCTGGACATGGGTGGCTACTACATCACCACGCGGGCCCAGTTCGA
ATCCGTGCAGGACCTGGTGCGGCACTACATGGAAGTGAATGACGGTCTATGCTACTTGCTCACG
GCACCCTGTATGGTCATGAAGCCCCAGACTCTAGGCCTGGCTAAGGATGCCTGGGAGATCGACC
GTAACTCCATAGCACTTGACCGCAGGCTGGGCACCGGCTGCTTTGGAGACGTGTGGCTGGGCAC
GTGGAACTGTAGCACAAAGGTGGCAGTGAAAACGCTGAAGCCAGGCACCATGTCGCCGAAGGCC
TTCCTGGAGGAGGCACAGATCATGAAACTGCTGAGGCACGACAAGCTGGTGCAGCTGTACGCGG
TGGTGTCAGAGGAACCCATTTATATTGTGACAGAGTTCATGTGCTATGGTAGCTTGCTGGATTT
CCTAAAGGATCGAAAGGGTCACAACTTGATGCTGCCCAATCTAGTGGACATGGCTGCCCAGGTA
GCAGAGGGCATGGCCTACATGGAGCGCATGAACTATATCCACCGAGACCTGAGAGCAGCCAACA
TCCTGGTGGGGGAACATCTAATATGCAAGATCGCTGACTTTGGGTTGGCACGCCTCATAGTGGA
TGATGAGTACAACCCCCAACAAGGAACCAAGTTTCCCATCAAGTGGACAGCCCCAGAGGCTGCT
CTCTTTGGCAGATTCACTGTCAAATCAGACGTGTGGTCCTTTGGGATTCTGCTCACTGAACTGA
TCACCAAGGGCAGAGTTCCATACCCAGGTATGAACAACCGGGAAGTGTTGGAACAGGTAGAGCA
CGGCTACCACATGCCATGCCCTCCGGGATGCCCAGTATCCCTGTATGAGGTCATGGAGCAGACC
TGGCGTCTGGATCCAGAGGAGAGGCCCACCTTTGAGTACCTGCAGTCTTTCCTGGAAGACTATT
TCACCTCCACAGAACCACAGTATCAGCCCGGAGACCAGACATAGCCTGACTGGGTATCAGTGAC
CCTCTGAGACTATGTACTAACCCTTGCCAATCCCCAGGGCACTCTGGTCCCAGTGCCCCGAGAC
TTGGAACCCTGTGGAATCCTAGCACGTCGGAAAAAGTCCGAAGCTCTGAAGCCATTTTATAGAG
GGTGCAAATGGAGACTAGAAATTCATCTCTTACCTTCGCTGGCCCCAAGCACTCTTTCTTCCCT
TCCCACCCATGCCCCATGCAAAAATCTAGGGCACCCAGTCATTTCACAGACGGAGTAAATGGAT
GCTCAGAGTTCATCTCTCGTACACTCTGACCCCAGTACCATTTTTCCTGTCCCATTAGGCTCCT
ACGTACCGTTAGTCCCCCCCCCATCTCCTAAAAATACTCATACATTGTGTAGTTATTTATAAAA
TTGTATTTCTCTTCTTCCACTTACCTCTTATCCCTGCTTTCTAACCTCCTGTCAGCCCGCTCCA
GCCCAGACCTTAAGAGTTTAATTCTGAGGTTCTCTTGGGTTTCTCTACGTTACAAAGGCAGGGG
ACGTCTCTGCTTGATTCCCCGTCTTCAGACTGGATGCTGTGGTCCAGGCCCAGGTCTGAAGGAG
AGAGCCATTGAAGGCTCACCATCTCTCTGAGTGGTCTGAATGTGTTTATTCGTTATAAACGAAC
AGTGATGATCGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_077059	(Get FASTA)	NCBI Sequence Viewer
	XP_006239141	(Get FASTA)	NCBI Sequence Viewer
	XP_006239142	(Get FASTA)	NCBI Sequence Viewer
	XP_006239143	(Get FASTA)	NCBI Sequence Viewer
	XP_006239144	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH62025	(Get FASTA)	NCBI Sequence Viewer
	CAA40337	(Get FASTA)	NCBI Sequence Viewer
	EDL80655	(Get FASTA)	NCBI Sequence Viewer
	EDL80656	(Get FASTA)	NCBI Sequence Viewer
	EDL80657	(Get FASTA)	NCBI Sequence Viewer
	Q6P6U0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_077059 ⟸ NM_024145

- UniProtKB:

Q6P6U0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG
TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ
AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD
MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR
LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI
VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC
KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP
GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ
PGDQT

hide sequence

RefSeq Acc Id:	XP_006239143 ⟸ XM_006239081
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239144 ⟸ XM_006239082
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239142 ⟸ XM_006239080
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:	XP_006239141 ⟸ XM_006239079
- Peptide Label:	isoform X1
- UniProtKB:	Q6P6U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSG TGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQ AEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLD MGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRR LGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI VTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLIC KIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYP GMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQ PGDQT hide sequence

RefSeq Acc Id:

ENSRNOP00000075272 ⟸ ENSRNOT00000085674

RefSeq Acc Id:

ENSRNOP00000013779 ⟸ ENSRNOT00000013778

Protein Domains

Protein kinase SH2 SH3

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694108

Promoter ID:

EPDNEW_R4631

Type:

single initiation site

Name:

Fgr_1

Description:

FGR proto-oncogene, Src family tyrosine kinase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	151,172,228 - 151,172,288	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621319	AgrOrtholog
Ensembl Genes	ENSRNOG00000009912	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000013779	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000075272	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013778	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000085674	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.505.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5623501	IMAGE-MGC_LOAD
InterPro	Fgr_SH2	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH2_dom_sf	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
	Tyr_kinase_AS	UniProtKB/Swiss-Prot
	Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:79113	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72428	IMAGE-MGC_LOAD
NCBI Gene	79113	ENTREZGENE
Pfam	Pkinase_Tyr	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH3_1	UniProtKB/Swiss-Prot
PhenoGen	Fgr	PhenoGen
PRINTS	SH2DOMAIN	UniProtKB/Swiss-Prot
	SH3DOMAIN	UniProtKB/Swiss-Prot
	TYRKINASE	UniProtKB/Swiss-Prot
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
SMART	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
	TyrKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50044	UniProtKB/Swiss-Prot
	SSF55550	UniProtKB/Swiss-Prot
	SSF56112	UniProtKB/Swiss-Prot
UniGene	Rn.11309	ENTREZGENE
UniProt	FGR_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q63206	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-07-23	Fgr	FGR proto-oncogene, Src family tyrosine kinase	Fgr	feline Gardner-Rasheed sarcoma viral oncogene	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-07-18	Fgr	feline Gardner-Rasheed sarcoma viral oncogene	Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-29	Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog		FGR	Name updated	1299863	APPROVED
2002-08-07	Fgr	FGR			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)