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Gene: Fgr (FGR proto-oncogene, Src family tyrosine kinase) Rattus norvegicus
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Symbol: Fgr
Name: FGR proto-oncogene, Src family tyrosine kinase
Description: Exhibits protein tyrosine kinase activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of secretion by cell; and regulation of kinase activity. Localizes to the cytosol and plasma membrane. Predicted to colocalize with the actin cytoskeleton and ruffle membrane. Orthologous to human FGR (FGR proto-oncogene, Src family tyrosine kinase); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: feline Gardner-Rasheed sarcoma viral oncogene; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; p55-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase Fgr; tyrosine-protein kinase Fgr
Orthologs:
Homo sapiens (human) : FGR (FGR proto-oncogene, Src family tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Fgr (FGR proto-oncogene, Src family tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgr (FGR proto-oncogene, Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : FGR (FGR proto-oncogene, Src family tyrosine kinase)
Canis lupus familiaris (dog) : FGR (FGR proto-oncogene, Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgr (FGR proto-oncogene, Src family tyrosine kinase)
Sus scrofa (pig) : FGR (FGR proto-oncogene, Src family tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05151,172,189 - 151,199,746 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5151,172,206 - 151,199,745 (+)Ensembl
Rnor_5.05154,839,086 - 154,866,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,119,455 - 152,147,057 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15152,129,494 - 152,157,096 (-)NCBI
Celera5143,612,003 - 143,639,441 (+)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map5977.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fgr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621319
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.