Lin28a (lin-28 homolog A) - Rat Genome Database

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Gene: Lin28a (lin-28 homolog A) Rattus norvegicus
Analyze
Symbol: Lin28a
Name: lin-28 homolog A
RGD ID: 1566408
Description: Predicted to enable several functions, including RNA binding activity; polysome binding activity; and translation initiation factor binding activity. Predicted to be involved in several processes, including RNA metabolic process; positive regulation of intracellular signal transduction; and regulation of gene expression. Predicted to act upstream of or within several processes, including miRNA metabolic process; negative regulation of glial cell differentiation; and regulation of gene expression. Predicted to be located in several cellular components, including cytoplasmic ribonucleoprotein granule; nucleolus; and rough endoplasmic reticulum. Predicted to be active in cytoplasm and nucleus. Orthologous to human LIN28A (lin-28 homolog A); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lin-28 homolog; lin-28 homolog (C. elegans); lin-28 homolog A (C. elegans); Lin28; LOC500562; LOC503116; RGD1566408; similar to lin-28 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Lin28c  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25146,227,119 - 146,244,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,227,119 - 146,244,122 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5148,930,214 - 148,947,205 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,699,834 - 150,716,825 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,686,401 - 150,703,397 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,230,343 - 152,247,873 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,230,343 - 152,247,332 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,917,438 - 155,935,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,730,997 - 152,766,317 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5144,647,207 - 144,664,072 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12798299   PMID:17473174   PMID:17617744   PMID:18292307   PMID:18604195   PMID:18951094   PMID:19578360   PMID:19703396   PMID:19898466   PMID:20014101   PMID:20179095   PMID:21247876  
PMID:21962509   PMID:23102813   PMID:24700281   PMID:24732380   PMID:26045559   PMID:28671666   PMID:32710472   PMID:33691905   PMID:33749722   PMID:36106579   PMID:37572229  


Genomics

Comparative Map Data
Lin28a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25146,227,119 - 146,244,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,227,119 - 146,244,122 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5148,930,214 - 148,947,205 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,699,834 - 150,716,825 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,686,401 - 150,703,397 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,230,343 - 152,247,873 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,230,343 - 152,247,332 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,917,438 - 155,935,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,730,997 - 152,766,317 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5144,647,207 - 144,664,072 (-)NCBICelera
Cytogenetic Map5q36NCBI
LIN28A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,410,817 - 26,429,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,410,817 - 26,429,728 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,737,308 - 26,756,219 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,609,856 - 26,628,806 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,421,410 - 26,440,350NCBI
Celera125,134,507 - 25,153,439 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,991,870 - 25,010,565 (+)NCBIHuRef
CHM1_1126,850,273 - 26,869,222 (+)NCBICHM1_1
T2T-CHM13v2.0126,248,852 - 26,267,747 (+)NCBIT2T-CHM13v2.0
Lin28a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,730,641 - 133,746,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,730,641 - 133,746,152 (-)EnsemblGRCm39 Ensembl
GRCm384134,003,330 - 134,019,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,003,330 - 134,018,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,559,245 - 133,574,731 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,275,406 - 133,290,892 (-)NCBIMGSCv36mm8
Celera4132,180,714 - 132,196,406 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
Lin28a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,793,583 - 5,808,662 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,793,583 - 5,808,662 (+)NCBIChiLan1.0ChiLan1.0
LIN28A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11199,539,757 - 199,559,961 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,674,751 - 25,693,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,739,267 - 26,758,028 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,739,268 - 26,758,028 (+)Ensemblpanpan1.1panPan2
LIN28A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,638,438 - 73,656,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,614,531 - 73,628,211 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,614,531 - 73,628,211 (-)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,189,783 - 70,233,550 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,176,232 - 74,219,851 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,177,683 - 74,191,364 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,001,039 - 71,044,831 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,006,779 - 72,050,518 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,035,491 - 73,054,057 (-)NCBIUU_Cfam_GSD_1.0
Lin28a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505845,071,230 - 45,087,075 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647410,896,153 - 10,909,247 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN28A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,806,056 - 83,818,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,806,178 - 83,818,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,358,779 - 77,371,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIN28A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,340,477 - 106,373,081 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603310,042,313 - 10,084,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lin28a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476410,426,168 - 10,441,541 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lin28a
86 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:169
Count of miRNA genes:134
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000058500
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

Markers in Region
BE113056  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04162,160,698 - 162,160,901UniSTSRnor5.0
Rnor_5.04161,779,204 - 161,779,407UniSTSRnor5.0
RGSC_v3.4495,842,110 - 95,842,313UniSTSRGSC3.4
Celera5144,647,246 - 144,647,450UniSTS
Celera490,141,672 - 90,141,875UniSTS
Cytogenetic Map5q36UniSTS
BE108055  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25146,212,439 - 146,212,602 (+)MAPPERmRatBN7.2
Rnor_6.05152,215,667 - 152,215,829NCBIRnor6.0
Rnor_5.05155,900,595 - 155,900,757UniSTSRnor5.0
RGSC_v3.45172,196,590 - 172,196,752UniSTSRGSC3.4
RGSC_v3.45152,732,724 - 152,732,886UniSTSRGSC3.4
Celera5144,632,531 - 144,632,693UniSTS
RH 3.4 Map5980.0UniSTS
Cytogenetic Map5q36UniSTS
RH137902  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25146,219,523 - 146,219,651 (+)MAPPERmRatBN7.2
Rnor_6.05152,222,750 - 152,222,877NCBIRnor6.0
Rnor_5.05155,907,677 - 155,907,804UniSTSRnor5.0
RGSC_v3.45152,739,806 - 152,739,933UniSTSRGSC3.4
Celera5144,639,614 - 144,639,741UniSTS
RH 3.4 Map5980.0UniSTS
Cytogenetic Map5q36UniSTS
AU049987  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25146,234,973 - 146,235,136 (-)MAPPERmRatBN7.2
mRatBN7.25146,234,973 - 146,235,136 (+)MAPPERmRatBN7.2
Rnor_6.076,044,603 - 6,044,765NCBIRnor6.0
Rnor_6.05152,238,193 - 152,238,355NCBIRnor6.0
Rnor_5.076,152,061 - 6,152,223UniSTSRnor5.0
Rnor_5.05155,926,355 - 155,926,517UniSTSRnor5.0
RGSC_v3.45152,756,504 - 152,756,666UniSTSRGSC3.4
Celera5144,654,933 - 144,655,095UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 6 6 6 8 13
Low 1 5 36 20 17 20 2 2 26 9 19 8 2
Below cutoff 2 12 9 9 2 9 6 9 34 14 9 3 6

Sequence


RefSeq Acc Id: ENSRNOT00000077165   ⟹   ENSRNOP00000071200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5152,230,343 - 152,247,332 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100729   ⟹   ENSRNOP00000085321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,227,119 - 146,244,122 (-)Ensembl
RefSeq Acc Id: NM_001109269   ⟹   NP_001102739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25146,227,119 - 146,244,122 (-)NCBI
Rnor_6.05152,230,343 - 152,247,332 (-)NCBI
Rnor_5.05155,917,438 - 155,935,517 (-)NCBI
RGSC_v3.45152,730,997 - 152,766,317 (-)RGD
Celera5144,647,207 - 144,664,072 (-)RGD
Sequence:
RefSeq Acc Id: XM_039110616   ⟹   XP_038966544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25146,229,653 - 146,243,739 (-)NCBI
RefSeq Acc Id: XM_039110617   ⟹   XP_038966545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25146,229,653 - 146,237,339 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966544 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966545 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL80696 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000085321
  ENSRNOP00000085321.1
RefSeq Acc Id: NP_001102739   ⟸   NM_001109269
- UniProtKB: D3ZZA6 (UniProtKB/TrEMBL),   A6ISZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071200   ⟸   ENSRNOT00000077165
RefSeq Acc Id: XP_038966544   ⟸   XM_039110616
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966545   ⟸   XM_039110617
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000085321   ⟸   ENSRNOT00000100729
Protein Domains
CCHC-type   CSD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZA6-F1-model_v2 AlphaFold D3ZZA6 1-209 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566408 AgrOrtholog
BioCyc Gene G2FUF-39601 BioCyc
Ensembl Genes ENSRNOG00000060320 Ensembl
  ENSRNOG00000069459 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000100729 ENTREZGENE
  ENSRNOT00000100729.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  Zinc finger, CCHC-type UniProtKB/TrEMBL
InterPro Cold_shock_prot UniProtKB/TrEMBL
  CSP_DNA-bd UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Znf_CCHC UniProtKB/TrEMBL
  Znf_CCHC_sf UniProtKB/TrEMBL
KEGG Report rno:500562 UniProtKB/TrEMBL
NCBI Gene 500562 ENTREZGENE
PANTHER PROTEIN LIN-28 UniProtKB/TrEMBL
  PROTEIN LIN-28 HOMOLOG A UniProtKB/TrEMBL
Pfam CSD UniProtKB/TrEMBL
  zf-CCHC UniProtKB/TrEMBL
PhenoGen Lin28a PhenoGen
PRINTS COLDSHOCK UniProtKB/TrEMBL
PROSITE CSD_2 UniProtKB/TrEMBL
  ZF_CCHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000060320 RatGTEx
  ENSRNOG00000069459 RatGTEx
SMART CSP UniProtKB/TrEMBL
  ZnF_C2HC UniProtKB/TrEMBL
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
  SSF57756 UniProtKB/TrEMBL
UniProt A6ISZ6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZA6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Lin28a  lin-28 homolog A  LOC503116  similar to lin-28 homolog  Data merged from RGD:1598183 737654 PROVISIONAL
2016-03-01 Lin28a  lin-28 homolog A  Lin28a  lin-28 homolog A (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Lin28a  lin-28 homolog A (C. elegans)  Lin28  lin-28 homolog (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Lin28  lin-28 homolog (C. elegans)  RGD1566408_predicted  similar to lin-28 homolog (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC503116  similar to lin-28 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1566408_predicted  similar to lin-28 homolog (predicted)  LOC500562  similar to lin-28 homolog  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500562  similar to lin-28 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL