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Gene: Sesn2 (sestrin 2) Rattus norvegicus
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Symbol: Sesn2
Name: sestrin 2
Description: Predicted to have several functions, including GDP-dissociation inhibitor activity; leucine binding activity; and sulfiredoxin activity. Predicted to be involved in several processes, including cellular response to starvation; intracellular signal transduction; and regulation of cellular protein metabolic process. Predicted to colocalize with GATOR2 complex; TORC2 complex; and protein kinase complex. Orthologous to human SESN2 (sestrin 2); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (+)-schisandrin B; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC502988; LOC502988; RGD1566319; sestrin-2; similar to Sestrin 2 (Hi95); uncharacterized protein LOC502988
Orthologs:
Homo sapiens (human) : SESN2 (sestrin 2)  HGNC  Alliance
Mus musculus (house mouse) : Sesn2 (sestrin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sesn2 (sestrin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SESN2 (sestrin 2)
Canis lupus familiaris (dog) : SESN2 (sestrin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sesn2 (sestrin 2)
Sus scrofa (pig) : SESN2 (sestrin 2)
Chlorocebus sabaeus (African green monkey) : SESN2 (sestrin 2)
Heterocephalus glaber (naked mole-rat) : Sesn2 (sestrin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05150,684,891 - 150,703,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,684,133 - 150,704,117 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05154,351,297 - 154,370,252 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,639,951 - 152,655,828 (+)NCBIRGSC3.4rn4RGSC3.4
Celera5143,128,904 - 143,147,855 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
  
More on Sesn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566319
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-30
Status: ACTIVE



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