(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SESN2 mRNA] CTD PMID:31150632 (-)-demecolcine increases expression ISO RGD:1346813 6480464 Demecolcine results in increased expression of SESN2 mRNA CTD PMID:23649840 (E)-thiamethoxam increases expression ISO RGD:1618969 6480464 Thiamethoxam results in increased expression of SESN2 mRNA CTD PMID:33533595 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:1346813 6480464 o, p'-DDT results in increased expression of SESN2 mRNA CTD PMID:18204070 17beta-estradiol increases expression ISO RGD:1346813 6480464 Estradiol results in increased expression of SESN2 mRNA CTD PMID:20106945 17beta-estradiol decreases expression ISO RGD:1346813 6480464 Estradiol results in decreased expression of SESN2 mRNA CTD PMID:19167446 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1346813 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1618969 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SESN2 promoter] CTD PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SESN2 mRNA CTD PMID:33387578 , PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1618969 6480464 Tetrachlorodibenzodioxin affects the expression of SESN2 mRNA CTD PMID:21570461 2-acetamidofluorene increases expression ISO RGD:1618969 6480464 2-Acetylaminofluorene results in increased expression of SESN2 mRNA CTD PMID:21607683 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:1618969 6480464 [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of SESN2 mRNA, [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of SESN2 protein CTD PMID:25637945 4-hydroxynon-2-enal decreases expression ISO RGD:1618969 6480464 4-hydroxy-2-nonenal results in decreased expression of SESN2 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:1618969 6480464 Fenretinide results in increased expression of SESN2 mRNA CTD PMID:28973697 4-phenylbutyric acid multiple interactions ISO RGD:1618969 6480464 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of SESN2 mRNA], 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of SESN2 protein] CTD PMID:32407927 5-fluorouracil multiple interactions ISO RGD:1346813 6480464 TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN2 mRNA] CTD PMID:15016801 5-fluorouracil increases expression ISO RGD:1346813 6480464 Fluorouracil results in increased expression of SESN2 mRNA CTD PMID:22525470 acrylamide increases expression ISO RGD:1346813 6480464 Acrylamide results in increased expression of SESN2 mRNA CTD PMID:32763439 actinomycin D multiple interactions ISO RGD:1346813 6480464 Dactinomycin inhibits the reaction [erastin results in increased expression of SESN2 mRNA] CTD PMID:31323261 aflatoxin B1 affects expression ISO RGD:1346813 6480464 Aflatoxin B1 affects the expression of SESN2 protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:1346813 6480464 Aflatoxin B1 results in increased methylation of SESN2 3' UTR CTD PMID:30157460 aflatoxin B1 increases expression ISO RGD:1346813 6480464 Aflatoxin B1 results in increased expression of SESN2 mRNA CTD PMID:21632981 more ... aflatoxin B1 increases expression ISO RGD:1618969 6480464 Aflatoxin B1 results in increased expression of SESN2 mRNA CTD PMID:19770486 Aflatoxin B2 alpha increases methylation ISO RGD:1346813 6480464 aflatoxin B2 results in increased methylation of SESN2 3' UTR CTD PMID:30157460 alternariol increases expression ISO RGD:1618969 6480464 alternariol results in increased expression of SESN2 protein CTD PMID:25456271 AM-251 increases expression ISO RGD:1346813 6480464 AM 251 results in increased expression of SESN2 mRNA CTD PMID:16500647 amino acid multiple interactions ISO RGD:1618969 6480464 EIF2AK4 gene mutant form inhibits the reaction [Amino Acids deficiency results in increased expression of SESN2 mRNA] CTD PMID:29449374 amino acid increases expression ISO RGD:1618969 6480464 Amino Acids deficiency results in increased expression of SESN2 mRNA CTD PMID:29449374 amiodarone increases expression ISO RGD:1346813 6480464 Amiodarone results in increased expression of SESN2 mRNA CTD PMID:19774075 antimycin A increases expression ISO RGD:1346813 6480464 Antimycin A results in increased expression of SESN2 mRNA CTD PMID:33512557 arsenite(3-) multiple interactions ISO RGD:1346813 6480464 arsenite inhibits the reaction [G3BP1 protein binds to SESN2 mRNA] CTD PMID:32406909 arsenous acid multiple interactions ISO RGD:1346813 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 mRNA] more ... CTD PMID:29662624 arsenous acid increases expression ISO RGD:1346813 6480464 Arsenic Trioxide results in increased expression of SESN2 mRNA, Arsenic Trioxide results in increased expression of SESN2 protein CTD PMID:24356939 , PMID:29662624 azathioprine increases expression ISO RGD:1346813 6480464 Azathioprine results in increased expression of SESN2 mRNA CTD PMID:22623647 azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 benzalkonium chloride decreases expression ISO RGD:1618969 6480464 Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 benzene increases expression ISO RGD:1346813 6480464 Benzene results in increased expression of SESN2 mRNA CTD PMID:20359517 , PMID:21843810 benzene-1,2,4-triol multiple interactions ISO RGD:1346813 6480464 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of SESN2 mRNA] CTD PMID:24530881 benzene-1,2,4-triol increases expression ISO RGD:1346813 6480464 hydroxyhydroquinone results in increased expression of SESN2 mRNA CTD PMID:24530881 benzo[a]pyrene affects expression ISO RGD:1346813 6480464 Benzo(a)pyrene affects the expression of SESN2 mRNA CTD PMID:21873647 benzo[a]pyrene increases methylation ISO RGD:1346813 6480464 Benzo(a)pyrene results in increased methylation of SESN2 3' UTR, Benzo(a)pyrene results in increased methylation of SESN2 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:1618969 6480464 Benzo(a)pyrene results in increased methylation of SESN2 intron CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:1618969 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SESN2 mRNA CTD PMID:27858113 benzo[a]pyrene increases expression ISO RGD:1346813 6480464 Benzo(a)pyrene results in increased expression of SESN2 mRNA CTD PMID:20064835 more ... benzo[a]pyrene decreases expression ISO RGD:1346813 6480464 Benzo(a)pyrene metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 benzo[a]pyrene increases expression ISO RGD:1618969 6480464 Benzo(a)pyrene metabolite results in increased expression of SESN2 mRNA, Benzo(a)pyrene results in increased expression of SESN2 mRNA CTD PMID:19770486 more ... benzo[b]fluoranthene increases expression ISO RGD:1618969 6480464 benzo(b)fluoranthene results in increased expression of SESN2 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:1618969 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SESN2 mRNA CTD PMID:27858113 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SESN2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1346813 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of SESN2 gene CTD PMID:31601247 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SESN2 mRNA CTD PMID:30816183 more ... bisphenol A affects expression ISO RGD:1346813 6480464 bisphenol A affects the expression of SESN2 mRNA CTD PMID:30903817 bisphenol A increases expression ISO RGD:1346813 6480464 bisphenol A results in increased expression of SESN2 mRNA CTD PMID:29275510 bisphenol A increases methylation ISO RGD:1618969 6480464 bisphenol A results in increased methylation of SESN2 promoter CTD PMID:27312807 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of SESN2 mRNA CTD PMID:32479839 butanal increases expression ISO RGD:1346813 6480464 butyraldehyde results in increased expression of SESN2 mRNA CTD PMID:26079696 butylated hydroxyanisole multiple interactions ISO RGD:1346813 6480464 Butylated Hydroxyanisole inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 cadmium atom increases expression ISO RGD:1346813 6480464 Cadmium results in increased expression of SESN2 mRNA CTD PMID:24284285 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SESN2 mRNA CTD PMID:31077537 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SESN2 mRNA CTD PMID:31077537 cannabidiol increases expression ISO RGD:1346813 6480464 Cannabidiol results in increased expression of SESN2 mRNA CTD PMID:26504004 , PMID:33244087 cannabidiol multiple interactions ISO RGD:1346813 6480464 [Dronabinol co-treated with Cannabidiol] results in increased expression of SESN2 mRNA CTD PMID:26504004 carbamazepine affects expression ISO RGD:1346813 6480464 Carbamazepine affects the expression of SESN2 mRNA CTD PMID:25979313 chloroprene increases expression ISO RGD:1618969 6480464 Chloroprene results in increased expression of SESN2 mRNA CTD PMID:23125180 chlorpyrifos multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 chlorpyrifos increases expression ISO RGD:1618969 6480464 Chlorpyrifos results in increased expression of SESN2 mRNA CTD PMID:34289071 chrysene decreases expression ISO RGD:1618969 6480464 chrysene results in decreased expression of SESN2 mRNA CTD PMID:26377693 chrysene multiple interactions ISO RGD:1618969 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SESN2 mRNA CTD PMID:27858113 cisplatin increases expression ISO RGD:1346813 6480464 Cisplatin results in increased expression of SESN2 mRNA CTD PMID:21532991 , PMID:27594783 clofibrate decreases expression ISO RGD:1618969 6480464 Clofibrate results in decreased expression of SESN2 mRNA CTD PMID:23811191 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of SESN2 mRNA CTD PMID:24386269 copper atom multiple interactions ISO RGD:1346813 6480464 [Chelating Agents binds to Copper] which results in increased expression of SESN2 mRNA, [NSC 689534 binds to Copper] which results in increased expression of SESN2 mRNA CTD PMID:20971185 , PMID:30911355 copper(0) multiple interactions ISO RGD:1346813 6480464 [Chelating Agents binds to Copper] which results in increased expression of SESN2 mRNA, [NSC 689534 binds to Copper] which results in increased expression of SESN2 mRNA CTD PMID:20971185 , PMID:30911355 copper(II) sulfate increases expression ISO RGD:1346813 6480464 Copper Sulfate results in increased expression of SESN2 mRNA CTD PMID:19549813 coumestrol decreases expression ISO RGD:1346813 6480464 Coumestrol results in decreased expression of SESN2 mRNA CTD PMID:19167446 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of SESN2 mRNA CTD PMID:26577399 , PMID:27523638 cycloheximide multiple interactions ISO RGD:1618969 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein], Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of SESN2 protein] CTD PMID:25637945 cycloheximide decreases expression ISO RGD:1618969 6480464 Cycloheximide results in decreased expression of SESN2 protein CTD PMID:25637945 cyclophosphamide decreases expression ISO RGD:1346813 6480464 Cyclophosphamide metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 cyclosporin A increases expression ISO RGD:1618969 6480464 Cyclosporine results in increased expression of SESN2 mRNA CTD PMID:25224403 cyclosporin A increases expression ISO RGD:1346813 6480464 Cyclosporine results in increased expression of SESN2 mRNA CTD PMID:20106945 more ... cyclosporin A affects expression ISO RGD:1346813 6480464 Cyclosporine affects the expression of SESN2 mRNA CTD PMID:25224403 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of SESN2 mRNA CTD PMID:23640034 deguelin increases expression ISO RGD:1346813 6480464 deguelin results in increased expression of SESN2 mRNA CTD PMID:33512557 desferrioxamine B multiple interactions ISO RGD:1346813 6480464 Deferoxamine inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 diallyl disulfide multiple interactions EXP 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SESN2 mRNA CTD PMID:31077537 diarsenic trioxide increases expression ISO RGD:1346813 6480464 Arsenic Trioxide results in increased expression of SESN2 mRNA, Arsenic Trioxide results in increased expression of SESN2 protein CTD PMID:24356939 , PMID:29662624 diarsenic trioxide multiple interactions ISO RGD:1346813 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 mRNA] more ... CTD PMID:29662624 dibenz[a,h]anthracene increases expression ISO RGD:1618969 6480464 1 more ... CTD PMID:26377693 dibenziodolium multiple interactions ISO RGD:1346813 6480464 diphenyleneiodonium inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 dichloromethane increases expression ISO RGD:1346813 6480464 Methylene Chloride results in increased expression of SESN2 mRNA CTD PMID:20359517 Didecyldimethylammonium increases expression ISO RGD:1346813 6480464 didecyldimethylammonium results in increased expression of SESN2 mRNA CTD PMID:32763356 dioxygen multiple interactions ISO RGD:1618969 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SESN2 mRNA CTD PMID:30529165 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of SESN2 mRNA CTD PMID:33729688 disodium selenite increases expression ISO RGD:1346813 6480464 Sodium Selenite results in increased expression of SESN2 mRNA CTD PMID:24383545 diuron decreases expression EXP 6480464 Diuron results in decreased expression of SESN2 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1346813 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:1346813 6480464 Doxorubicin results in increased expression of SESN2 mRNA CTD PMID:29803840 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SESN2 mRNA CTD PMID:29391264 erastin multiple interactions ISO RGD:1346813 6480464 Acetylcysteine inhibits the reaction [erastin results in increased expression of SESN2 protein] more ... CTD PMID:31323261 erastin increases expression ISO RGD:1618969 6480464 erastin results in increased expression of SESN2 mRNA, erastin results in increased expression of SESN2 protein CTD PMID:31323261 erastin increases expression ISO RGD:1346813 6480464 erastin results in increased expression of SESN2 mRNA, erastin results in increased expression of SESN2 protein CTD PMID:31323261 erastin multiple interactions ISO RGD:1618969 6480464 NFE2L2 protein affects the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 ethanol multiple interactions ISO RGD:1346813 6480464 [Ethanol co-treated with Folic Acid] results in decreased expression of SESN2 mRNA more ... CTD PMID:23378141 , PMID:34405320 ethanol decreases expression ISO RGD:1346813 6480464 Ethanol results in decreased expression of SESN2 protein CTD PMID:34405320 ethanol multiple interactions ISO RGD:1618969 6480464 pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein] more ... CTD PMID:34405320 ethanol decreases expression ISO RGD:1618969 6480464 Ethanol results in decreased expression of SESN2 protein CTD PMID:34405320 ethanol affects expression ISO RGD:1618969 6480464 Ethanol affects the expression of SESN2 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:1346813 6480464 Ethyl Methanesulfonate results in increased expression of SESN2 mRNA CTD PMID:23649840 ethylbenzene increases expression ISO RGD:1346813 6480464 ethylbenzene results in increased expression of SESN2 mRNA CTD PMID:20359517 fenamidone increases expression ISO RGD:1618969 6480464 fenamidone results in increased expression of SESN2 mRNA CTD PMID:27029645 fenpyroximate increases expression ISO RGD:1346813 6480464 fenpyroximate results in increased expression of SESN2 mRNA CTD PMID:33512557 ferrostatin-1 multiple interactions ISO RGD:1346813 6480464 ferrostatin-1 inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 fluoranthene multiple interactions ISO RGD:1618969 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of SESN2 mRNA CTD PMID:28329830 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of SESN2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1346813 6480464 [Ethanol co-treated with Folic Acid] results in decreased expression of SESN2 mRNA, [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of SESN2 mRNA CTD PMID:23378141 , PMID:24657277 formaldehyde increases expression ISO RGD:1346813 6480464 Formaldehyde results in increased expression of SESN2 mRNA CTD PMID:17938736 more ... fulvestrant multiple interactions ISO RGD:1346813 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of SESN2 gene CTD PMID:31601247 furan decreases expression EXP 6480464 furan results in decreased expression of SESN2 mRNA CTD PMID:22079235 furan increases expression ISO RGD:1618969 6480464 furan results in increased expression of SESN2 mRNA CTD PMID:24183702 gamma-hexachlorocyclohexane increases expression ISO RGD:1346813 6480464 Hexachlorocyclohexane results in increased expression of SESN2 mRNA CTD PMID:24356939 genistein increases expression ISO RGD:1346813 6480464 Genistein results in increased expression of SESN2 mRNA CTD PMID:26865667 genistein increases expression ISO RGD:1618969 6480464 Genistein results in increased expression of SESN2 mRNA CTD PMID:32186404 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SESN2 mRNA CTD PMID:33387578 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of SESN2 mRNA CTD PMID:20621112 glutathione multiple interactions ISO RGD:1346813 6480464 Glutathione inhibits the reaction [1 more ... CTD PMID:26035713 glyphosate multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 hemin affects response to substance ISO RGD:1618969 6480464 SESN2 protein affects the susceptibility to Hemin CTD PMID:31054940 hemin increases expression ISO RGD:1346813 6480464 Hemin results in increased expression of SESN2 protein CTD PMID:31054940 hemin multiple interactions ISO RGD:1346813 6480464 [Antineoplastic Agents binds to and results in decreased activity of NFE2L2 protein] inhibits the reaction [Hemin results in increased expression of SESN2 protein] more ... CTD PMID:31054940 hemin multiple interactions ISO RGD:1618969 6480464 [SESN2 protein affects the susceptibility to Hemin] which results in decreased expression of CASP3 protein modified form CTD PMID:31054940 hydrogen peroxide increases expression ISO RGD:1618969 6480464 Hydrogen Peroxide results in increased expression of SESN2 mRNA CTD PMID:31054940 hydrogen peroxide multiple interactions EXP 6480464 [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] more ... CTD PMID:32275923 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of SESN2 mRNA, Hydrogen Peroxide results in increased expression of SESN2 protein CTD PMID:32275923 hydrogen peroxide multiple interactions ISO RGD:1346813 6480464 Saponins inhibits the reaction [Hydrogen Peroxide results in decreased expression of SESN2 mRNA] CTD PMID:29274434 hydrogen peroxide decreases expression ISO RGD:1346813 6480464 Hydrogen Peroxide results in decreased expression of SESN2 mRNA CTD PMID:29274434 hydroquinone increases expression ISO RGD:1346813 6480464 hydroquinone results in increased expression of SESN2 mRNA CTD PMID:23416264 , PMID:31256213 imidacloprid multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of SESN2 mRNA CTD PMID:21396975 indoline multiple interactions EXP 6480464 [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] CTD PMID:32275923 irinotecan increases expression ISO RGD:1346813 6480464 Irinotecan metabolite results in increased expression of SESN2 mRNA, Irinotecan results in increased expression of SESN2 mRNA CTD PMID:15956246 isorhamnetin multiple interactions ISO RGD:1346813 6480464 [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of SESN2 mRNA CTD PMID:24211276 L-ascorbic acid multiple interactions ISO RGD:1346813 6480464 [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA, nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA] CTD PMID:20530418 leflunomide increases expression ISO RGD:1346813 6480464 leflunomide results in increased expression of SESN2 mRNA CTD PMID:28988120 levofloxacin increases expression EXP 6480464 Levofloxacin results in increased expression of SESN2 mRNA CTD PMID:24136188 Licochalcone B increases expression ISO RGD:1346813 6480464 licochalcone B results in increased expression of SESN2 mRNA CTD PMID:33647349 lipopolysaccharide multiple interactions ISO RGD:1346813 6480464 JUN protein promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of SESN2 protein] more ... CTD PMID:25637945 lipopolysaccharide increases expression ISO RGD:1618969 6480464 Lipopolysaccharides results in increased expression of SESN2 mRNA CTD PMID:25637945 lipopolysaccharide multiple interactions ISO RGD:1618969 6480464 [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of SESN2 mRNA more ... CTD PMID:25637945 luteolin multiple interactions ISO RGD:1346813 6480464 [Luteolin results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of SESN2 mRNA, SESN2 protein promotes the reaction [Luteolin inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]] CTD PMID:32407927 luteolin increases expression ISO RGD:1346813 6480464 Luteolin results in increased expression of SESN2 mRNA, Luteolin results in increased expression of SESN2 protein CTD PMID:32407927 luteolin multiple interactions ISO RGD:1618969 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of SESN2 mRNA], Luteolin inhibits the reaction [Tunicamycin results in increased expression of SESN2 protein] CTD PMID:32407927 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of SESN2 mRNA CTD PMID:28801915 mercury dibromide multiple interactions ISO RGD:1346813 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN2 mRNA CTD PMID:27188386 metformin multiple interactions ISO RGD:1618969 6480464 [Metformin co-treated with Rotenone] results in increased expression of SESN2 protein CTD PMID:26031332 metformin decreases expression EXP 6480464 Metformin results in decreased expression of SESN2 mRNA CTD PMID:31324951 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of SESN2 mRNA CTD PMID:28619521 methotrexate multiple interactions ISO RGD:1346813 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of SESN2 mRNA CTD PMID:24657277 methotrexate increases expression ISO RGD:1346813 6480464 Methotrexate results in increased expression of SESN2 mRNA CTD PMID:24657277 methyl methanesulfonate increases expression ISO RGD:1346813 6480464 Methyl Methanesulfonate results in increased expression of SESN2 mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO RGD:1346813 6480464 methylmercuric chloride results in increased expression of SESN2 mRNA CTD PMID:23179753 , PMID:28001369 motexafin gadolinium multiple interactions ISO RGD:1346813 6480464 [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA more ... CTD PMID:16357179 , PMID:20530418 motexafin gadolinium increases expression ISO RGD:1346813 6480464 motexafin gadolinium results in increased expression of SESN2 mRNA CTD PMID:16357179 N-acetyl-L-cysteine multiple interactions ISO RGD:1346813 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 mRNA] more ... CTD PMID:24535669 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1618969 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein], Lipopolysaccharides inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of SESN2 protein] CTD PMID:25637945 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases ubiquitination ISO RGD:1618969 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of SESN2 protein CTD PMID:25637945 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:1618969 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SESN2 protein CTD PMID:25637945 N-methyl-4-phenylpyridinium increases expression ISO RGD:1346813 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SESN2 mRNA CTD PMID:24810058 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SESN2 mRNA CTD PMID:28801915 N-nitrosodiethylamine increases expression ISO RGD:1618969 6480464 Diethylnitrosamine results in increased expression of SESN2 mRNA CTD PMID:21607683 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of SESN2 mRNA CTD PMID:24136188 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of SESN2 mRNA CTD PMID:24136188 Nutlin-3 multiple interactions ISO RGD:1346813 6480464 nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA] CTD PMID:20530418 o-xylene increases expression ISO RGD:1346813 6480464 2-xylene results in increased expression of SESN2 mRNA CTD PMID:20359517 ochratoxin A decreases expression ISO RGD:1346813 6480464 ochratoxin A metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SESN2 mRNA CTD PMID:25729387 p-chloromercuribenzoic acid increases expression ISO RGD:1346813 6480464 p-Chloromercuribenzoic Acid results in increased expression of SESN2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1346813 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN2 mRNA CTD PMID:27188386 paracetamol affects expression ISO RGD:1618969 6480464 Acetaminophen affects the expression of SESN2 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SESN2 mRNA CTD PMID:33387578 paracetamol decreases expression ISO RGD:1618969 6480464 Acetaminophen results in decreased expression of SESN2 protein CTD PMID:28209544 paracetamol multiple interactions ISO RGD:1618969 6480464 SESN2 protein inhibits the reaction [Acetaminophen results in decreased expression of GPT protein] more ... CTD PMID:28209544 paracetamol increases expression ISO RGD:1346813 6480464 Acetaminophen results in increased expression of SESN2 mRNA CTD PMID:21420995 more ... peptidoglycan increases expression ISO RGD:1618969 6480464 Peptidoglycan results in increased expression of SESN2 mRNA CTD PMID:25637945 perfluorononanoic acid increases expression ISO RGD:1346813 6480464 perfluoro-n-nonanoic acid results in increased expression of SESN2 mRNA CTD PMID:32588087 phenobarbital affects expression ISO RGD:1346813 6480464 Phenobarbital affects the expression of SESN2 mRNA CTD PMID:19159669 phenylhydrazine multiple interactions ISO RGD:1618969 6480464 SESN2 protein inhibits the reaction [phenylhydrazine results in increased activity of GPT protein], SESN2 protein inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein] CTD PMID:31323261 phenylmercury acetate increases expression ISO RGD:1346813 6480464 Phenylmercuric Acetate results in increased expression of SESN2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1346813 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN2 mRNA CTD PMID:27188386 picoxystrobin increases expression ISO RGD:1346813 6480464 picoxystrobin results in increased expression of SESN2 mRNA CTD PMID:33512557 pirinixic acid increases expression ISO RGD:1618969 6480464 pirinixic acid results in increased expression of SESN2 mRNA CTD PMID:23811191 poly(I:C) increases expression ISO RGD:1618969 6480464 Poly I-C results in increased expression of SESN2 mRNA CTD PMID:25637945 progesterone increases expression ISO RGD:1346813 6480464 Progesterone results in increased expression of SESN2 mRNA CTD PMID:18037150 propanal increases expression ISO RGD:1346813 6480464 propionaldehyde results in increased expression of SESN2 mRNA CTD PMID:26079696 pterostilbene multiple interactions ISO RGD:1346813 6480464 pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein] more ... CTD PMID:34405320 pterostilbene multiple interactions ISO RGD:1618969 6480464 pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein] more ... CTD PMID:34405320 pyrimidifen increases expression ISO RGD:1346813 6480464 pyrimidifen results in increased expression of SESN2 mRNA CTD PMID:33512557 quercetin multiple interactions ISO RGD:1346813 6480464 [pifithrin co-treated with Quercetin] results in increased expression of SESN2 protein more ... CTD PMID:24535669 quercetin increases expression ISO RGD:1346813 6480464 Quercetin results in increased expression of SESN2 mRNA, Quercetin results in increased expression of SESN2 protein CTD PMID:21632981 , PMID:24535669 resveratrol decreases expression ISO RGD:1346813 6480464 resveratrol results in decreased expression of SESN2 mRNA CTD PMID:19167446 resveratrol increases expression ISO RGD:1346813 6480464 resveratrol results in increased expression of SESN2 mRNA, resveratrol results in increased expression of SESN2 protein CTD PMID:23651738 , PMID:25533949 resveratrol multiple interactions ISO RGD:1346813 6480464 PARP1 protein affects the reaction [resveratrol results in increased expression of SESN2 protein], STF-118804 inhibits the reaction [resveratrol results in increased expression of SESN2 protein] CTD PMID:25533949 rotenone multiple interactions ISO RGD:1618969 6480464 [Metformin co-treated with Rotenone] results in increased expression of SESN2 protein more ... CTD PMID:26031332 rotenone decreases expression ISO RGD:1346813 6480464 Rotenone results in decreased expression of SESN2 mRNA CTD PMID:29955902 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SESN2 mRNA CTD PMID:28374803 rotenone increases expression EXP 6480464 Rotenone results in increased expression of SESN2 protein CTD PMID:26031332 rotenone increases expression ISO RGD:1618969 6480464 Rotenone results in increased expression of SESN2 mRNA, Rotenone results in increased expression of SESN2 protein CTD PMID:26031332 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO RGD:1346813 6480464 S-(1, 2-dichlorovinyl)cysteine results in increased expression of SESN2 mRNA CTD PMID:33725128 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:1346813 6480464 Buthionine Sulfoximine results in increased expression of SESN2 protein CTD PMID:31323261 SB 203580 multiple interactions ISO RGD:1346813 6480464 [SB 203580 co-treated with Quercetin] results in increased expression of SESN2 protein CTD PMID:24535669 SB 431542 multiple interactions ISO RGD:1346813 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide increases expression ISO RGD:1618969 6480464 Silicon Dioxide results in increased expression of SESN2 mRNA CTD PMID:19073995 silicon dioxide increases expression ISO RGD:1346813 6480464 Silicon Dioxide analog results in increased expression of SESN2 mRNA CTD PMID:25895662 silver atom increases expression ISO RGD:1346813 6480464 Silver results in increased expression of SESN2 mRNA CTD PMID:26014281 , PMID:28959546 silver(0) increases expression ISO RGD:1346813 6480464 Silver results in increased expression of SESN2 mRNA CTD PMID:26014281 , PMID:28959546 simvastatin increases expression ISO RGD:1618969 6480464 Simvastatin results in increased expression of SESN2 mRNA CTD PMID:19262002 sirolimus multiple interactions ISO RGD:1346813 6480464 [(+)-JQ1 compound co-treated with Sirolimus] affects the expression of SESN2 mRNA CTD PMID:25307878 sorafenib increases expression ISO RGD:1346813 6480464 Sorafenib results in increased expression of SESN2 protein CTD PMID:31323261 sunitinib increases expression ISO RGD:1346813 6480464 Sunitinib results in increased expression of SESN2 mRNA CTD PMID:31533062 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of SESN2 protein CTD PMID:32740777 tert-butyl hydroperoxide increases expression ISO RGD:1618969 6480464 tert-Butylhydroperoxide results in increased expression of SESN2 protein CTD PMID:32740777 tetrachloroethene increases expression ISO RGD:1618969 6480464 Tetrachloroethylene results in increased expression of SESN2 mRNA CTD PMID:28973375 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SESN2 mRNA] CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SESN2 mRNA CTD PMID:31150632 tetraphene decreases expression ISO RGD:1618969 6480464 benz(a)anthracene results in decreased expression of SESN2 mRNA CTD PMID:26377693 tetraphene multiple interactions ISO RGD:1618969 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SESN2 mRNA CTD PMID:27858113 thapsigargin increases expression ISO RGD:1346813 6480464 Thapsigargin results in increased expression of SESN2 mRNA CTD PMID:22378314 thiabendazole multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 thiamethoxam increases expression ISO RGD:1618969 6480464 Thiamethoxam results in increased expression of SESN2 mRNA CTD PMID:33533595 thiazoles multiple interactions EXP 6480464 [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] CTD PMID:32275923 thifluzamide increases expression ISO RGD:1346813 6480464 thifluzamide results in increased expression of SESN2 mRNA CTD PMID:33512557 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of SESN2 mRNA CTD PMID:34492290 toluene increases expression ISO RGD:1346813 6480464 Toluene results in increased expression of SESN2 mRNA CTD PMID:20359517 topotecan increases expression EXP 6480464 Topotecan results in increased expression of SESN2 mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SESN2 mRNA CTD PMID:25729387 trichloroethene increases expression ISO RGD:1346813 6480464 Trichloroethylene results in increased expression of SESN2 mRNA CTD PMID:20359517 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SESN2 mRNA CTD PMID:33387578 trichostatin A affects expression ISO RGD:1346813 6480464 trichostatin A affects the expression of SESN2 mRNA CTD PMID:28542535 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1346813 6480464 tris(2-butoxyethyl) phosphate affects the expression of SESN2 mRNA CTD PMID:29024780 troglitazone increases expression ISO RGD:1346813 6480464 troglitazone results in increased expression of SESN2 mRNA CTD PMID:19140230 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of SESN2 protein CTD PMID:32740777 tunicamycin increases expression ISO RGD:1618969 6480464 Tunicamycin results in increased expression of SESN2 mRNA, Tunicamycin results in increased expression of SESN2 protein CTD PMID:32407927 , PMID:32740777 tunicamycin multiple interactions ISO RGD:1346813 6480464 SESN2 protein inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein], SESN2 protein promotes the reaction [Luteolin inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]] CTD PMID:32407927 tunicamycin multiple interactions ISO RGD:1618969 6480464 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of SESN2 mRNA] more ... CTD PMID:32407927 , PMID:32740777 tunicamycin increases expression ISO RGD:1346813 6480464 Tunicamycin results in increased expression of SESN2 mRNA CTD PMID:22378314 more ... tunicamycin multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:32740777 urethane increases expression ISO RGD:1346813 6480464 Urethane results in increased expression of SESN2 mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of SESN2 mRNA CTD PMID:24136188 valproic acid increases expression ISO RGD:1346813 6480464 Valproic Acid results in increased expression of SESN2 mRNA CTD PMID:23179753 , PMID:29154799 vincristine increases expression ISO RGD:1346813 6480464 Vincristine results in increased expression of SESN2 mRNA CTD PMID:23649840 zinc acetate multiple interactions ISO RGD:1346813 6480464 [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA more ... CTD PMID:16357179 , PMID:20530418 zinc acetate increases expression ISO RGD:1346813 6480464 Zinc Acetate results in increased expression of SESN2 mRNA CTD PMID:16357179 zinc atom multiple interactions ISO RGD:1346813 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SESN2 mRNA CTD PMID:18593933 zinc sulfate multiple interactions ISO RGD:1346813 6480464 Zinc Sulfate inhibits the reaction [prolinedithiocarbamate results in increased expression of SESN2 mRNA] CTD PMID:18951928 zinc(0) multiple interactions ISO RGD:1346813 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SESN2 mRNA CTD PMID:18593933