Nbl1 (NBL1, DAN family BMP antagonist) - Rat Genome Database

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Gene: Nbl1 (NBL1, DAN family BMP antagonist) Rattus norvegicus
Analyze
Symbol: Nbl1
Name: NBL1, DAN family BMP antagonist
RGD ID: 3151
Description: Predicted to enable BMP binding activity; identical protein binding activity; and morphogen activity. Predicted to be involved in several processes, including determination of dorsal identity; negative regulation of BMP signaling pathway; and negative regulation of monocyte chemotaxis. Predicted to act upstream of or within neuron projection morphogenesis and positive regulation of neuron differentiation. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Orthologous to several human genes including NBL1 (NBL1, DAN family BMP antagonist); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: N03; neuroblastoma 1; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma suppression of tumorigenicity 1; Neuroblastoma suppression of tumorigenicity 1 (DNA segment human D1S1733E); neuroblastoma suppressor of tumorigenicity 1; neuroblastoma, suppression of tumorigenicity 1; Neuroblastoma, suppression of tumorigenicity 1 (DNA segment human D1S1733E); zinc finger protein DAN
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,601,986 - 156,613,182 (-)NCBIGRCr8
mRatBN7.25151,318,752 - 151,329,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,015,980 - 154,027,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,790,290 - 155,801,487 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,772,293 - 155,783,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,524,569 - 157,535,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,263,765 - 161,274,897 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5149,703,598 - 149,714,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
DDE  (ISO)
dexamethasone  (EXP)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dimethylarsinic acid  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycine betaine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
propylparaben  (ISO)
raloxifene  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
testosterone  (EXP,ISO)
thiram  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular region  (IEA)
extracellular space  (IBA,IEA,ISO,ISS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts. Ozaki T and Sakiyama S, Proc Natl Acad Sci U S A 1993 Apr 1;90(7):2593-7.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7942277   PMID:9268694   PMID:9660951   PMID:10390159   PMID:11594460   PMID:15528323   PMID:16325379   PMID:22357543   PMID:23063586   PMID:23676271   PMID:25561725  


Genomics

Comparative Map Data
Nbl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,601,986 - 156,613,182 (-)NCBIGRCr8
mRatBN7.25151,318,752 - 151,329,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,015,980 - 154,027,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,790,290 - 155,801,487 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,772,293 - 155,783,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,524,569 - 157,535,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,263,765 - 161,274,897 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5149,703,598 - 149,714,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
NBL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,643,229 - 19,658,452 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,596,979 - 19,658,456 (+)EnsemblGRCh38hg38GRCh38
GRCh37119,969,723 - 19,984,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,842,313 - 19,857,532 (+)NCBINCBI36Build 36hg18NCBI36
Build 34119,715,031 - 19,730,251NCBI
Celera118,296,492 - 18,311,717 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef118,215,821 - 18,231,031 (+)NCBIHuRef
CHM1_1120,078,997 - 20,094,228 (+)NCBICHM1_1
T2T-CHM13v2.0119,466,606 - 19,481,830 (+)NCBIT2T-CHM13v2.0
Nbl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,809,602 - 138,820,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,809,595 - 138,820,304 (-)EnsemblGRCm39 Ensembl
GRCm384139,082,291 - 139,093,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,082,284 - 139,092,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,638,207 - 138,648,885 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,354,368 - 138,364,941 (-)NCBIMGSCv36mm8
Celera4140,868,231 - 140,871,576 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
Nbl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452308,573 - 319,989 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955452316,867 - 319,883 (+)NCBIChiLan1.0ChiLan1.0
NBL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,460,724 - 207,474,909 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,577,562 - 206,591,747 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,599,121 - 18,613,305 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,652,853 - 19,656,431 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,641,279 - 19,656,431 (+)Ensemblpanpan1.1panPan2
NBL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,040,206 - 79,102,792 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,041,105 - 79,102,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,554,895 - 75,582,497 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,607,161 - 79,634,902 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,608,223 - 79,610,312 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,425,235 - 76,452,808 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,434,195 - 77,461,836 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,503,885 - 78,531,526 (-)NCBIUU_Cfam_GSD_1.0
Nbl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505839,996,034 - 40,018,509 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,840,240 - 5,859,749 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,820,798 - 5,843,291 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NBL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,059,392 - 78,071,604 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,046,084 - 78,071,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2672,138,765 - 72,142,022 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NBL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,893,928 - 112,908,041 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,893,633 - 112,897,355 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,253,483 - 3,267,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nbl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247644,764,903 - 4,775,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247644,771,334 - 4,774,462 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nbl1
41 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:99
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000072299
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat

Markers in Region
AA963347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,318,773 - 151,318,925 (+)MAPPERmRatBN7.2
Rnor_6.05157,524,591 - 157,524,742NCBIRnor6.0
Rnor_5.05161,263,787 - 161,263,938UniSTSRnor5.0
Celera5149,703,620 - 149,703,771UniSTS
RH 3.4 Map51032.4UniSTS
Cytogenetic Map5q36.13UniSTS
AU047985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,326,895 - 151,327,192 (+)MAPPERmRatBN7.2
Rnor_6.05157,532,649 - 157,532,945NCBIRnor6.0
Rnor_5.05161,271,845 - 161,272,141UniSTSRnor5.0
Cytogenetic Map5q36.13UniSTS
UniSTS:224311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,319,532 - 151,319,694 (+)MAPPERmRatBN7.2
Rnor_6.05157,525,350 - 157,525,511NCBIRnor6.0
Rnor_5.05161,264,546 - 161,264,707UniSTSRnor5.0
Celera5149,704,379 - 149,704,540UniSTS
Cytogenetic Map5q36.13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 90 60 36 36 45 237 112 109 57 24
Low 51 167 147 33 147 13 36
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000072299   ⟹   ENSRNOP00000064345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,318,754 - 151,329,948 (-)Ensembl
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101272   ⟹   ENSRNOP00000079581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)Ensembl
RefSeq Acc Id: NM_031609   ⟹   NP_113797
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,601,986 - 156,613,182 (-)NCBI
mRatBN7.25151,318,752 - 151,329,948 (-)NCBI
Rnor_6.05157,524,569 - 157,535,701 (-)NCBI
Rnor_5.05161,263,765 - 161,274,897 (-)NCBI
Celera5149,703,598 - 149,714,771 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113797 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB32215 (Get FASTA)   NCBI Sequence Viewer  
  AAH61833 (Get FASTA)   NCBI Sequence Viewer  
  CAA47344 (Get FASTA)   NCBI Sequence Viewer  
  EDL80903 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064345.1
  ENSRNOP00000079581.1
GenBank Protein Q06880 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113797   ⟸   NM_031609
- Peptide Label: precursor
- UniProtKB: Q6P750 (UniProtKB/Swiss-Prot),   Q06880 (UniProtKB/Swiss-Prot),   A0A0G2JSZ3 (UniProtKB/TrEMBL),   A6ITK2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064345   ⟸   ENSRNOT00000072299
Ensembl Acc Id: ENSRNOP00000079581   ⟸   ENSRNOT00000101272
Protein Domains
CTCK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q06880-F1-model_v2 AlphaFold Q06880 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694199
Promoter ID:EPDNEW_R4724
Type:multiple initiation site
Name:Nbl1_1
Description:neuroblastoma 1, DAN family BMP antagonist
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05157,535,676 - 157,535,736EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3151 AgrOrtholog
BioCyc Gene G2FUF-39429 BioCyc
Ensembl Genes ENSRNOG00000049402 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072299.3 UniProtKB/TrEMBL
  ENSRNOT00000101272.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599381 IMAGE-MGC_LOAD
InterPro Cys_knot_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuroblast_suppress_tumour_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:50594 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72398 IMAGE-MGC_LOAD
NCBI Gene 50594 ENTREZGENE
PANTHER GREMLIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nbl1 PhenoGen
PIRSF DAN_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049402 RatGTEx
SMART SM00041 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMZ3_RAT UniProtKB/TrEMBL
  A6ITK2 ENTREZGENE, UniProtKB/TrEMBL
  NBL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P750 ENTREZGENE
UniProt Secondary Q6P750 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-18 Nbl1  NBL1, DAN family BMP antagonist  Nbl1  neuroblastoma 1, DAN family BMP antagonist  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-07 Nbl1  neuroblastoma 1, DAN family BMP antagonist  Nbl1  neuroblastoma 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-06 Nbl1  neuroblastoma 1  Nbl1  neuroblastoma, suppression of tumorigenicity 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Nbl1  neuroblastoma, suppression of tumorigenicity 1    neuroblastoma, suppression of tumorigenicity 1   Symbol and Name status set to approved 625702 APPROVED
2002-06-10 Nbl1  neuroblastoma, suppression of tumorigenicity 1       Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a putative zinc-finger domain and a proline-rich domain 729039
gene_protein 178 amino acid residues 729039