E2f2 (E2F transcription factor 2) - Rat Genome Database

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Gene: E2f2 (E2F transcription factor 2) Rattus norvegicus
Analyze
Symbol: E2f2
Name: E2F transcription factor 2
RGD ID: 1593939
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of sprouting angiogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including DNA-templated transcription; intrinsic apoptotic signaling pathway by p53 class mediator; and lens fiber cell apoptotic process. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human E2F2 (E2F transcription factor 2); INTERACTS WITH gentamycin; trichloroethene; (S)-nicotine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC684111; similar to E2F transcription factor 2; transcription factor E2F2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25148,399,193 - 148,422,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,399,642 - 148,421,217 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05154,516,611 - 154,540,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,522,119 - 154,540,265 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,290,231 - 158,313,411 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5146,801,415 - 146,824,688 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3',5'-cyclic AMP  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-nitrophenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
auraptene  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cilostazol  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
eugenol  (ISO)
folic acid  (ISO)
folpet  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GW 3965  (ISO)
harmine  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
lidocaine  (ISO)
linsidomine  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nicotine  (ISO)
nitrogen dioxide  (ISO)
ochratoxin A  (ISO)
palbociclib  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
ritonavir  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
thapsigargin  (ISO)
toluene 2,4-diisocyanate  (ISO)
trametinib  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice. Iglesias A, etal., J Clin Invest 2004 May;113(10):1398-407.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7739537   PMID:10082561   PMID:11095619   PMID:15735762   PMID:16360038   PMID:23332764   PMID:27731397   PMID:34519914  


Genomics

Comparative Map Data
E2f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25148,399,193 - 148,422,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,399,642 - 148,421,217 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05154,516,611 - 154,540,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,522,119 - 154,540,265 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,290,231 - 158,313,411 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5146,801,415 - 146,824,688 (+)NCBICelera
Cytogenetic Map5q36NCBI
E2F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,505,212 - 23,531,233 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl123,506,438 - 23,531,233 (-)EnsemblGRCh38hg38GRCh38
GRCh37123,832,930 - 23,857,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,705,509 - 23,730,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 34123,578,227 - 23,603,019NCBI
Celera122,162,636 - 22,187,415 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef122,083,477 - 22,108,254 (-)NCBIHuRef
CHM1_1123,945,595 - 23,970,369 (-)NCBICHM1_1
T2T-CHM13v2.0123,340,999 - 23,365,799 (-)NCBIT2T-CHM13v2.0
E2f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,899,585 - 135,923,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4135,899,705 - 135,923,368 (+)EnsemblGRCm39 Ensembl
GRCm384136,172,274 - 136,196,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,172,394 - 136,196,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv374135,728,309 - 135,751,972 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,444,470 - 135,466,790 (+)NCBIMGSCv36mm8
Celera4134,369,818 - 134,393,475 (+)NCBICelera
Cytogenetic Map4D3NCBI
E2f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,494,919 - 3,518,487 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554523,498,077 - 3,518,033 (-)NCBIChiLan1.0ChiLan1.0
E2F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1123,683,291 - 23,707,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,683,293 - 23,707,951 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0122,696,695 - 22,722,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
E2F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,901,009 - 75,923,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,901,058 - 75,923,255 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,471,074 - 72,493,421 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,460,446 - 76,482,801 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,459,883 - 76,480,634 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,282,735 - 73,305,077 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,289,942 - 74,312,301 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,295,343 - 75,317,658 (+)NCBIUU_Cfam_GSD_1.0
E2f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505842,893,125 - 42,912,970 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364748,719,253 - 8,737,763 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364748,719,243 - 8,739,811 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E2F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,377,924 - 81,398,867 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1681,377,922 - 81,398,862 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
E2F2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120109,146,567 - 109,171,540 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20109,146,587 - 109,168,093 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660337,158,767 - 7,183,756 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E2f2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247648,135,470 - 8,157,731 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247648,132,283 - 8,158,190 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in E2f2
124 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:93
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000072618
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

Markers in Region
D5Uwm41  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25148,394,176 - 148,394,316 (+)MAPPERmRatBN7.2
Rnor_6.05154,510,987 - 154,511,126NCBIRnor6.0
Rnor_5.05158,285,268 - 158,285,407UniSTSRnor5.0
RGSC_v3.45154,960,463 - 154,960,603RGDRGSC3.4
RGSC_v3.45154,960,464 - 154,960,603UniSTSRGSC3.4
RGSC_v3.15154,970,502 - 154,970,642RGD
Celera5146,796,699 - 146,796,838UniSTS
Cytogenetic Map5 RGD


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 12 26 18 19 18 18 12 5 1
Low 1 31 31 23 23 8 11 56 23 36 10 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000072618   ⟹   ENSRNOP00000067839
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5148,399,642 - 148,421,217 (+)Ensembl
Rnor_6.0 Ensembl5154,522,119 - 154,540,265 (+)Ensembl
RefSeq Acc Id: XM_003750061   ⟹   XP_003750109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,399,193 - 148,422,595 (+)NCBI
Rnor_6.05154,516,611 - 154,540,228 (+)NCBI
Rnor_5.05158,290,231 - 158,313,411 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593850   ⟹   XP_017449339
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,407,768 - 148,422,595 (+)NCBI
Rnor_6.05154,525,191 - 154,540,228 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003750109 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449339 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003750109   ⟸   XM_003750061
- Peptide Label: isoform X1
- UniProtKB: M0RDX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449339   ⟸   XM_017593850
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000067839   ⟸   ENSRNOT00000072618
Protein Domains
E2F/DP family winged-helix DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RDX6-F1-model_v2 AlphaFold M0RDX6 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593939 AgrOrtholog
BioCyc Gene G2FUF-39511 BioCyc
Ensembl Genes ENSRNOG00000047741 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000067839 ENTREZGENE
  ENSRNOP00000067839.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072618 ENTREZGENE
  ENSRNOT00000072618.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  6.10.250.540 UniProtKB/TrEMBL
InterPro E2F UniProtKB/TrEMBL
  E2F-DP_heterodim UniProtKB/TrEMBL
  E2F_CC-MB UniProtKB/TrEMBL
  E2F_TDP UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene 684111 ENTREZGENE
PANTHER PTHR12081 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR E2F2 UniProtKB/TrEMBL
Pfam E2F_CC-MB UniProtKB/TrEMBL
  E2F_TDP UniProtKB/TrEMBL
PhenoGen E2f2 PhenoGen
SMART E2F_TDP UniProtKB/TrEMBL
Superfamily-SCOP SSF144074 UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt M0RDX6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-13 E2f2  E2F transcription factor 2  LOC684111  similar to E2F transcription factor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC684111  similar to E2F transcription factor 2      Symbol and Name status set to provisional 70820 PROVISIONAL