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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Atp6v0b | Rat | 1,2-dichloroethane | decreases expression | ISO | RGD:1317998 | 6480464 | ethylene dichloride results in decreased expression of ATP6V0B mRNA | CTD | PMID:28960355 | Atp6v0b | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1317998 | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0B mRNA | CTD | PMID:22206623 | Atp6v0b | Rat | 17beta-estradiol | decreases expression | ISO | RGD:1317998 | 6480464 | Estradiol results in decreased expression of ATP6V0B mRNA | CTD | PMID:39298647 | Atp6v0b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1317998 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATP6V0B mRNA | CTD | PMID:19465110 | Atp6v0b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATP6V0B mRNA | CTD | PMID:34747641 | Atp6v0b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1317998 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATP6V0B mRNA | CTD | PMID:21570461 | Atp6v0b | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1317997 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Atp6v0b | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | RGD:1317998 | 6480464 | bisphenol S results in decreased expression of ATP6V0B mRNA | CTD | PMID:39298647 | Atp6v0b | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ATP6V0B mRNA | CTD | PMID:30047161 | Atp6v0b | Rat | acetylsalicylic acid | decreases expression | ISO | RGD:1317997 | 6480464 | Aspirin results in decreased expression of ATP6V0B mRNA | CTD | PMID:15928584 | Atp6v0b | Rat | acrylamide | increases expression | ISO | RGD:1317997 | 6480464 | Acrylamide results in increased expression of ATP6V0B mRNA | CTD | PMID:32763439 | Atp6v0b | Rat | all-trans-retinoic acid | increases expression | ISO | RGD:1317997 | 6480464 | Tretinoin results in increased expression of ATP6V0B mRNA | CTD | PMID:33167477 | Atp6v0b | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of ATP6V0B mRNA | CTD | PMID:30047161 | Atp6v0b | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of ATP6V0B mRNA | CTD | PMID:30779732 | Atp6v0b | Rat | antirheumatic drug | decreases expression | ISO | RGD:1317997 | 6480464 | Antirheumatic Agents results in decreased expression of ATP6V0B mRNA | CTD | PMID:24449571 | Atp6v0b | Rat | aristolochic acid A | increases expression | ISO | RGD:1317997 | 6480464 | aristolochic acid I results in increased expression of ATP6V0B mRNA | CTD | PMID:33212167 | Atp6v0b | Rat | Aroclor 1254 | increases expression | ISO | RGD:1317998 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of ATP6V0B mRNA | CTD | PMID:23650126 | Atp6v0b | Rat | arsane | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | arsenic atom | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | arsenous acid | increases expression | ISO | RGD:1317997 | 6480464 | Arsenic Trioxide results in increased expression of ATP6V0B mRNA | CTD | PMID:29633893 | Atp6v0b | Rat | benzo[a]pyrene | increases expression | ISO | RGD:1317998 | 6480464 | Benzo(a)pyrene results in increased expression of ATP6V0B mRNA | CTD | PMID:22228805 | Atp6v0b | Rat | beta-lapachone | increases expression | ISO | RGD:1317997 | 6480464 | beta-lapachone results in increased expression of ATP6V0B mRNA | CTD | PMID:38218311 | Atp6v0b | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1317998 | 6480464 | Diethylhexyl Phthalate results in increased expression of ATP6V0B mRNA | CTD | PMID:33754040 | Atp6v0b | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ATP6V0B mRNA | CTD | PMID:25181051 | Atp6v0b | Rat | bisphenol A | decreases expression | ISO | RGD:1317998 | 6480464 | bisphenol A results in decreased expression of ATP6V0B mRNA | CTD | PMID:35598803 | Atp6v0b | Rat | bisphenol A | increases methylation | ISO | RGD:1317997 | 6480464 | bisphenol A results in increased methylation of ATP6V0B gene | CTD | PMID:31601247 | Atp6v0b | Rat | bisphenol A | increases expression | ISO | RGD:1317998 | 6480464 | bisphenol A results in increased expression of ATP6V0B mRNA | CTD | PMID:33221593|PMID:38074096 | Atp6v0b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATP6V0B mRNA | CTD | PMID:32145629 | Atp6v0b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ATP6V0B mRNA | CTD | PMID:30816183|PMID:32528016 | Atp6v0b | Rat | bisphenol A | affects expression | ISO | RGD:1317997 | 6480464 | bisphenol A affects the expression of ATP6V0B mRNA | CTD | PMID:30903817 | Atp6v0b | Rat | bisphenol A | decreases methylation | ISO | RGD:1317998 | 6480464 | bisphenol A results in decreased methylation of ATP6V0B promoter | CTD | PMID:27312807 | Atp6v0b | Rat | bisphenol F | multiple interactions | ISO | RGD:1317997 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Atp6v0b | Rat | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of ATP6V0B mRNA | CTD | PMID:24136188 | Atp6v0b | Rat | cadmium atom | increases expression | ISO | RGD:1317997 | 6480464 | Cadmium results in increased expression of ATP6V0B mRNA | CTD | PMID:24376830 | Atp6v0b | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of ATP6V0B promoter | CTD | PMID:22457795 | Atp6v0b | Rat | cadmium dichloride | increases expression | ISO | RGD:1317998 | 6480464 | Cadmium Chloride results in increased expression of ATP6V0B mRNA | CTD | PMID:30030080 | Atp6v0b | Rat | CGP 52608 | multiple interactions | ISO | RGD:1317997 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ATP6V0B gene] | CTD | PMID:28238834 | Atp6v0b | Rat | chlorpyrifos | increases expression | ISO | RGD:1317998 | 6480464 | Chlorpyrifos results in increased expression of ATP6V0B mRNA | CTD | PMID:37019170 | Atp6v0b | Rat | clobetasol | increases expression | ISO | RGD:1317998 | 6480464 | Clobetasol results in increased expression of ATP6V0B mRNA | CTD | PMID:27462272 | Atp6v0b | Rat | clofibrate | multiple interactions | ISO | RGD:1317998 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ATP6V0B mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Atp6v0b | Rat | clofibrate | decreases expression | ISO | RGD:1317998 | 6480464 | Clofibrate results in decreased expression of ATP6V0B mRNA | CTD | PMID:17585979 | Atp6v0b | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of ATP6V0B mRNA | CTD | PMID:24386269 | Atp6v0b | Rat | cobalt dichloride | increases expression | ISO | RGD:1317997 | 6480464 | cobaltous chloride results in increased expression of ATP6V0B mRNA | CTD | PMID:19320972 | Atp6v0b | Rat | copper(II) sulfate | increases expression | ISO | RGD:1317997 | 6480464 | Copper Sulfate results in increased expression of ATP6V0B mRNA | CTD | PMID:19549813 | Atp6v0b | Rat | crocidolite asbestos | increases expression | ISO | RGD:1317997 | 6480464 | Asbestos, Crocidolite results in increased expression of ATP6V0B mRNA | CTD | PMID:29523930 | Atp6v0b | Rat | cyclosporin A | increases expression | ISO | RGD:1317997 | 6480464 | Cyclosporine results in increased expression of ATP6V0B mRNA | CTD | PMID:20106945 | Atp6v0b | Rat | cyclosporin A | increases expression | ISO | RGD:1317998 | 6480464 | Cyclosporine results in increased expression of ATP6V0B mRNA | CTD | PMID:19770486 | Atp6v0b | Rat | dexamethasone | multiple interactions | ISO | RGD:1317997 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Atp6v0b | Rat | diarsenic trioxide | increases expression | ISO | RGD:1317997 | 6480464 | Arsenic Trioxide results in increased expression of ATP6V0B mRNA | CTD | PMID:29633893 | Atp6v0b | Rat | Dibutyl phosphate | affects expression | ISO | RGD:1317997 | 6480464 | di-n-butylphosphoric acid affects the expression of ATP6V0B mRNA | CTD | PMID:37042841 | Atp6v0b | Rat | dibutyl phthalate | increases expression | ISO | RGD:1317998 | 6480464 | Dibutyl Phthalate results in increased expression of ATP6V0B mRNA | CTD | PMID:17361019|PMID:21266533 | Atp6v0b | Rat | diuron | decreases expression | ISO | RGD:1317997 | 6480464 | Diuron results in decreased expression of ATP6V0B mRNA | CTD | PMID:35967413 | Atp6v0b | Rat | ethanol | multiple interactions | ISO | RGD:1317997 | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... | CTD | PMID:29432896 | Atp6v0b | Rat | ethanol | multiple interactions | ISO | RGD:1317998 | 6480464 | Ethanol affects the expression of and affects the splicing of ATP6V0B mRNA | CTD | PMID:30319688 | Atp6v0b | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ATP6V0B mRNA | CTD | PMID:24793618 | Atp6v0b | Rat | folic acid | multiple interactions | ISO | RGD:1317998 | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6V0B mRNA | CTD | PMID:22206623 | Atp6v0b | Rat | indometacin | multiple interactions | ISO | RGD:1317997 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Atp6v0b | Rat | irinotecan | increases response to substance | ISO | RGD:1317997 | 6480464 | ATP6V0B protein results in increased susceptibility to Irinotecan | CTD | PMID:16734730 | Atp6v0b | Rat | isobutanol | multiple interactions | ISO | RGD:1317997 | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic more ... | CTD | PMID:29432896 | Atp6v0b | Rat | isotretinoin | decreases expression | ISO | RGD:1317997 | 6480464 | Isotretinoin results in decreased expression of ATP6V0B mRNA | CTD | PMID:20436886 | Atp6v0b | Rat | maneb | multiple interactions | ISO | RGD:1317998 | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0B mRNA | CTD | PMID:18386188 | Atp6v0b | Rat | manganese atom | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | manganese(0) | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | manganese(II) chloride | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of ATP6V0B mRNA | CTD | PMID:30047161 | Atp6v0b | Rat | methyl methanesulfonate | increases expression | ISO | RGD:1317997 | 6480464 | Methyl Methanesulfonate results in increased expression of ATP6V0B mRNA | CTD | PMID:23649840 | Atp6v0b | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of ATP6V0B mRNA | CTD | PMID:24136188 | Atp6v0b | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of ATP6V0B mRNA | CTD | PMID:24136188 | Atp6v0b | Rat | ozone | multiple interactions | ISO | RGD:1317997 | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of ATP6V0B mRNA | CTD | PMID:35430440 | Atp6v0b | Rat | paracetamol | multiple interactions | ISO | RGD:1317998 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ATP6V0B mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Atp6v0b | Rat | paraquat | multiple interactions | ISO | RGD:1317998 | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0B mRNA | CTD | PMID:18386188 | Atp6v0b | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:1317998 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ATP6V0B mRNA | CTD | PMID:20936131 | Atp6v0b | Rat | phenobarbital | affects expression | ISO | RGD:1317998 | 6480464 | Phenobarbital affects the expression of ATP6V0B mRNA | CTD | PMID:23091169 | Atp6v0b | Rat | propiconazole | decreases expression | ISO | RGD:1317998 | 6480464 | propiconazole results in decreased expression of ATP6V0B mRNA | CTD | PMID:21278054 | Atp6v0b | Rat | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of ATP6V0B mRNA | CTD | PMID:30047161 | Atp6v0b | Rat | quercetin | decreases expression | ISO | RGD:1317997 | 6480464 | Quercetin results in decreased expression of ATP6V0B mRNA | CTD | PMID:15309432 | Atp6v0b | Rat | rotenone | increases expression | ISO | RGD:1317997 | 6480464 | Rotenone results in increased expression of ATP6V0B mRNA | CTD | PMID:31648047 | Atp6v0b | Rat | rotenone | decreases expression | ISO | RGD:1317997 | 6480464 | Rotenone results in decreased expression of ATP6V0B mRNA | CTD | PMID:33512557 | Atp6v0b | Rat | sodium arsenite | increases expression | ISO | RGD:1317997 | 6480464 | sodium arsenite results in increased expression of ATP6V0B mRNA | CTD | PMID:38568856 | Atp6v0b | Rat | sodium arsenite | multiple interactions | ISO | RGD:1317997 | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Atp6v0b | Rat | sodium dichromate | increases expression | ISO | RGD:1317998 | 6480464 | sodium bichromate results in increased expression of ATP6V0B mRNA | CTD | PMID:31558096 | Atp6v0b | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of ATP6V0B mRNA | CTD | PMID:30047161 | Atp6v0b | Rat | Tanshinone I | increases expression | ISO | RGD:1317997 | 6480464 | tanshinone results in increased expression of ATP6V0B mRNA | CTD | PMID:15849732 | Atp6v0b | Rat | tetrachloromethane | increases expression | ISO | RGD:1317998 | 6480464 | Carbon Tetrachloride results in increased expression of ATP6V0B mRNA | CTD | PMID:27339419|PMID:31919559 | Atp6v0b | Rat | titanium dioxide | decreases methylation | ISO | RGD:1317998 | 6480464 | titanium dioxide results in decreased methylation of ATP6V0B gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Atp6v0b | Rat | triphenyl phosphate | affects expression | ISO | RGD:1317997 | 6480464 | triphenyl phosphate affects the expression of ATP6V0B mRNA | CTD | PMID:37042841 | Atp6v0b | Rat | triptonide | affects expression | ISO | RGD:1317998 | 6480464 | triptonide affects the expression of ATP6V0B mRNA | CTD | PMID:33045310 | Atp6v0b | Rat | urethane | increases expression | ISO | RGD:1317997 | 6480464 | Urethane results in increased expression of ATP6V0B mRNA | CTD | PMID:28818685 | Atp6v0b | Rat | valproic acid | decreases methylation | ISO | RGD:1317997 | 6480464 | Valproic Acid results in decreased methylation of ATP6V0B gene | CTD | PMID:29154799 | Atp6v0b | Rat | valproic acid | affects expression | ISO | RGD:1317997 | 6480464 | Valproic Acid affects the expression of ATP6V0B mRNA | CTD | PMID:25979313 | Atp6v0b | Rat | valproic acid | increases expression | ISO | RGD:1317997 | 6480464 | Valproic Acid results in increased expression of ATP6V0B mRNA | CTD | PMID:23179753|PMID:28001369|PMID:29154799 | Atp6v0b | Rat | vanadium atom | decreases expression | ISO | RGD:1317997 | 6480464 | Vanadium results in decreased expression of ATP6V0B mRNA | CTD | PMID:19000753 | Atp6v0b | Rat | vanadium(0) | decreases expression | ISO | RGD:1317997 | 6480464 | Vanadium results in decreased expression of ATP6V0B mRNA | CTD | PMID:19000753 | |