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Gene: Gjb3 (gap junction protein, beta 3) Rattus norvegicus
Symbol: Gjb3
Name: gap junction protein, beta 3
Description: Predicted to have gap junction channel activity. Involved in several processes, including cellular response to retinoic acid; skin development; and spermatogenesis. Localizes to gap junction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2B; autosomal recessive nonsyndromic deafness 1A; erythrokeratodermia variabilis; and erythrokeratodermia variabilis et progressiva 1. Orthologous to human GJB3 (gap junction protein beta 3); INTERACTS WITH ammonium chloride; bisphenol A; endosulfan.
Type: protein-coding
Also known as: connexin c; connexin-31; cx31; Cxnc; gap junction beta-3 protein; gap junction membrane channel protein beta 3
Homo sapiens (human) : GJB3 (gap junction protein beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Gjb3 (gap junction protein, beta 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gjb3 (gap junction protein beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GJB3 (gap junction protein beta 3)
Canis lupus familiaris (dog) : GJB3 (gap junction protein beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gjb3 (gap junction protein beta 3)
Sus scrofa (pig) : GJB3 (gap junction protein beta 3)
Chlorocebus sabaeus (African green monkey) : GJB3 (gap junction protein beta 3)
Heterocephalus glaber (naked mole-rat) : Gjb3 (gap junction protein beta 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05145,390,590 - 145,397,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5145,391,311 - 145,392,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05149,158,599 - 149,164,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45146,771,804 - 146,772,616 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15146,781,842 - 146,782,655 (-)NCBI
Celera5138,143,911 - 138,144,723 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gjb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2695
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.