Ppcs (phosphopantothenoylcysteine synthetase)

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Gene: Ppcs (phosphopantothenoylcysteine synthetase) Rattus norvegicus

Analyze

Symbol:

Ppcs

Name:

phosphopantothenoylcysteine synthetase

RGD ID:

1311399

Description:

Predicted to enable phosphopantothenate--cysteine ligase activity and protein homodimerization activity. Predicted to be involved in acetyl-CoA biosynthetic process; coenzyme A biosynthetic process; and heart process. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2C. Orthologous to human PPCS (phosphopantothenoylcysteine synthetase); PARTICIPATES IN pantothenic acid metabolic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC298490; MGC116383; phosphopantothenate--cysteine ligase; RGD1311399; similar to RIKEN cDNA 6330579B17 gene

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPCS (phosphopantothenoylcysteine synthetase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ppcs (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppcs (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPCS (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPCS (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppcs (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPCS (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPCS (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppcs (phosphopantothenoylcysteine synthetase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ppcs (phosphopantothenoylcysteine synthetase)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PPCS (phosphopantothenoylcysteine synthetase)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppcs (phosphopantothenoylcysteine synthetase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CAB2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ppcs	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y71H2AM.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ppcs	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	133,023,077 - 133,026,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	133,023,121 - 133,026,933 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	135,751,606 - 135,755,020 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	137,508,062 - 137,511,476 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	137,528,672 - 137,532,086 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	138,466,298 - 138,470,108 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,466,293 - 138,470,096 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	142,276,595 - 142,279,846 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	140,008,434 - 140,012,295 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	140,013,626 - 140,017,910 (-)	NCBI
Celera	5	131,547,070 - 131,550,484 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

dilated cardiomyopathy 2C (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

amitrole (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

bromobenzene (EXP)

buspirone (EXP)

cadmium atom (ISO)

cisplatin (ISO)

clofibrate (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

decabromodiphenyl ether (EXP)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

dicrotophos (ISO)

endosulfan (EXP)

fenofibrate (EXP)

fenthion (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

gemfibrozil (EXP)

inulin (ISO)

ivermectin (ISO)

lead diacetate (ISO)

leflunomide (EXP)

levofloxacin (EXP)

menadione (ISO)

methapyrilene (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

Muraglitazar (EXP)

nefazodone (EXP)

nimesulide (EXP)

nitrofen (EXP)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenformin (EXP)

phorone (EXP)

pirinixic acid (EXP,ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

T-2 toxin (ISO)

tamoxifen (ISO)

temozolomide (ISO)

Tesaglitazar (EXP)

thioacetamide (EXP)

tremolite asbestos (ISO)

trichloroethene (EXP)

troglitazone (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetyl-CoA biosynthetic process (ISO)

coenzyme A biosynthetic process (IBA,ISO)

heart process (ISO)

Cellular Component

cytoplasm (IBA)

nucleus (IBA)

Molecular Function

identical protein binding (ISO)

phosphopantothenate--cysteine ligase activity (IBA,ISO)

protein homodimerization activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pantothenic acid metabolic pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:11923312	PMID:12477932	PMID:23376485	PMID:29754768

Genomics

Comparative Map Data

Ppcs
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	133,023,077 - 133,026,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	133,023,121 - 133,026,933 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	135,751,606 - 135,755,020 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	137,508,062 - 137,511,476 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	137,528,672 - 137,532,086 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	138,466,298 - 138,470,108 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,466,293 - 138,470,096 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	142,276,595 - 142,279,846 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	140,008,434 - 140,012,295 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	140,013,626 - 140,017,910 (-)	NCBI
Celera	5	131,547,070 - 131,550,484 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

PPCS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	42,456,341 - 42,473,417 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	42,456,117 - 42,473,385 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	42,922,012 - 42,939,088 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	42,694,760 - 42,698,673 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	41,204,112 - 41,208,024 (+)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	41,042,280 - 41,046,192 (+)	NCBI		HuRef
CHM1_1	1	43,039,012 - 43,042,924 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	42,326,703 - 42,343,779 (+)	NCBI		T2T-CHM13v2.0

Ppcs
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	119,275,724 - 119,279,673 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	119,275,727 - 119,279,617 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	119,418,527 - 119,422,440 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	119,418,530 - 119,422,420 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	119,091,138 - 119,095,025 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	118,916,465 - 118,920,352 (-)	NCBI		MGSCv36	mm8
Celera	4	118,149,698 - 118,153,626 (-)	NCBI		Celera
Cytogenetic Map	4	D2.1	NCBI
cM Map	4	55.38	NCBI

Ppcs
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955537	2,080,865 - 2,085,003 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955537	2,080,865 - 2,084,199 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPCS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	183,480,108 - 183,497,012 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	41,756,403 - 41,773,430 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	43,136,337 - 43,153,583 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	43,136,720 - 43,140,620 (+)	Ensembl	panpan1.1		panPan2

PPCS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	813,435 - 817,732 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	813,870 - 816,825 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	1,068,253 - 1,071,661 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	895,016 - 898,424 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	895,030 - 898,423 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	804,254 - 807,662 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	865,779 - 869,187 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	880,894 - 884,302 (-)	NCBI		UU_Cfam_GSD_1.0

Ppcs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	58,042,297 - 58,046,179 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	23,867,347 - 23,871,223 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936474	23,867,117 - 23,870,832 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPCS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	168,870,869 - 168,876,779 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	168,833,945 - 168,876,831 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	156,392,581 - 156,397,630 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPCS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	20	90,467,656 - 90,473,704 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	26,435,491 - 26,452,563 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppcs
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624892	1,791,255 - 1,795,250 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624892	1,791,254 - 1,794,866 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ppcs
21 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	286
Count of miRNA genes:	183
Interacting mature miRNAs:	212
Transcripts:	ENSRNOT00000011392
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	124160767	133749643	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1300122	Wbc1	White blood cell count QTL 1	2.75		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	5	125392826	139989768	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat

Markers in Region

RH128446

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	133,023,188 - 133,023,403 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	138,466,380 - 138,466,594	NCBI	Rnor6.0
Rnor_5.0	5	142,276,672 - 142,276,886	UniSTS	Rnor5.0
RGSC_v3.4	5	140,008,513 - 140,008,727	UniSTS	RGSC3.4
Celera	5	131,547,147 - 131,547,361	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	5	38	31	6	31			52	33	18
Low		38	19	10	13	10	8	11	22	2	23	11	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001039010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC099208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG378487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ195046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK474267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000011392 ⟹ ENSRNOP00000011392

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	133,023,121 - 133,026,933 (-)	Ensembl
Rnor_6.0 Ensembl	5	138,466,293 - 138,470,096 (-)	Ensembl

RefSeq Acc Id:

NM_001039010 ⟹ NP_001034099

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	133,023,112 - 133,026,528 (-)	NCBI
Rnor_6.0	5	138,466,303 - 138,469,734 (-)	NCBI
Rnor_5.0	5	142,276,595 - 142,279,846 (-)	NCBI
RGSC_v3.4	5	140,008,434 - 140,012,295 (-)	RGD
Celera	5	131,547,070 - 131,550,484 (-)	RGD

Sequence:

show sequence

ATGGCGGAAATGGACCTGGTGGCTGAGTTGCCGCGTCCCGAGGGTGCTGCGCGCTGGGCCGAGG
TTATGGCTCGCTTTGCGGCCAGGCTGGGCGAGCAGGGCCGGCGGGTGGTGCTGGTCACGTCTGG
AGGCACTAAGGTTCCTCTGGAAGCGCGAGCCGTGCGCTTTCTGGACAACTTCAGCAGCGGGCGA
CGCGGGGCAGCGTCGGCGGAGGTCTTCCTGGCTGCCGGCTATGGGGTCTTGTTCTTGTACCGAG
CACGCTCGGCCTTCCCCTACGCCCACCGCTTCCCGCCCCAGGCCTGGCTGTCAGCCCTTCGGCC
TTCTGGCCCAGCTCAATCGGGCAAGCTGAGTCTGGAGGCCGAAGAGAATGCACTCCCAGGCTTT
GCTGCAGCGTTGCAGGGCTACCAAGAGGCAGCTGCTGCCGGCACCTTCCTGGCTGTAGAGTTTA
CCACTTTGGCGGATTACCTGCATCTGCTGCAGGCTGCGGCCCTGGCTCTCAATCCATTAGGCTC
TTCTGCGATGTTTTACCTGGCCGCGGCAGTGTCAGATTTCTATATTCCTGTCTCTGAAATGCCT
GAACACAAGATCCACTCATCTGGTGGCCCACTGCAGATAACAATGAAGATGGTGCCGAAGATGC
TCTCTCCTCTGGTTAAGGACTGGGCTCCCAAAGCATTTATAGTTTCGTTCAAGCTGGAGACAGA
CCCGGACATCATCATTAGTCGGGCTCGGAATGCTCTGGAAGTTTACCAGCATCAAGTAGTGGTG
GCCAATATCCTGGAGTCAATAAAGTCCTTTGTGATTATTGTAACCAAAGACTCAGAGACAAAGT
TACTGCTGTCTGAGGACGAGGTAGCAAGAGGCATGGTGATAGAAGAGAAGATCGTAGACGACCT
TCGGTCTCGACACACAGCGTTTATATGTGACAGAAACTGAAGGGATGCTCCCCTAGGGTTAAAA
GCCGGGTTCTCACCACTGATGTGAACTAAAGTTAATCCTTTGTTAAGGATAAACACAGTGAAGA
AGTGGCAAAAAACAGTGTGCGGGCAAAGGCCTGTGAAACACTGGACACCTTGATCTGGAAAGTG
AACAAGATTCACAAAGACTGTGTGATTGCGTGTTCTGCAGAGCAGACGGGACTGGAGCTGCTGT
CTGTCAGCCTGCTGTACAGTAGAAAGATCGTAGGCGCATGAATGGTCATGCTCTGAAGAAGTAC
TTATCGAGTGCCTACCCTTTGCCAGGGCCTTTGTGCGCTGTGAGGGTCTGAAAGATGAGCGAGC
GTTGTCTCGTTTGGGACCTGGATGTACAAAAATGTATGTGCAATAAAGTGTGTGCCCATAAAGG
GACACTTGGAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008763998 ⟹ XP_008762220

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	133,023,109 - 133,026,899 (-)	NCBI
Rnor_6.0	5	138,466,298 - 138,470,108 (-)	NCBI

Sequence:

show sequence

TCCCATCTCAAAGGTTAAATGGCCAGAACTTGATTGCAATGTAGCCCGAGATTCGGGAGAGCTA
TATGGTGGCCGGTATAGGTAAAAAATAACCATTTCGTTTTCCAGACTAGGAAACCCACATGAAG
TATAATTTTTCTGGATTTTCGAGAAAGGTTCTTCTTCTCGATCCTCTTCGACTGGCTCTGACAG
AACAGCCAAGCATTTCAAGCCTTGGCGAGGTCAAGACTTAGTGGCGGACATAGGAAAGGGAATA
GGGACACAGTCACTATTTGCGGCTGCGCGCAGCTCAGGCTCTTCTGCGATGTTTTACCTGGCCG
CGGCAGTGTCAGATTTCTATATTCCTGTCTCTGAAATGCCTGAACACAAGATCCACTCATCTGG
TGGCCCACTGCAGATAACAATGAAGATGGTGCCGAAGATGCTCTCTCCTCTGGTTAAGGACTGG
GCTCCCAAAGCATTTATAGTTTCGTTCAAGCTGGAGACAGACCCGGACATCATCATTAGTCGGG
CTCGGAATGCTCTGGAAGTTTACCAGCATCAAGTAGTGGTGGCCAATATCCTGGAGTCAATAAA
GTCCTTTGTGATTATTGTAACCAAAGACTCAGAGACAAAGTTACTGCTGTCTGAGGACGAGGTA
GCAAGAGGCATGGTGATAGAAGAGAAGATCGTAGACGACCTTCGGTCTCGACACACAGCGTTTA
TATGTGACAGAAACTGAAGGGATGCTCCCCTAGGGTTAAAAGCCGGGTTCTCACCACTGATGTG
AACTAAAGTTAATCCTTTGTTAAGGATAAACACAGTGAAGAAGTGGCAAAAAACAGTGTGCGGG
CAAAGGCCTGTGAAACACTGGACACCTTGATCTGGAAAGTGAACAAGATTCACAAAGACTGTGT
GATTGCGTGTTCTGCAGAGCAGACGGGACTGGAGCTGCTGTCTGTCAGCCTGCTGTACAGTAGA
AAGATCGTAGGCGCATGAATGGTCATGCTCTGAAGAAGTACTTATCGAGTGCCTACCCTTTGCC
AGGGCCTTTGTGCGCTGTGAGGGTCTGAAAGATGAGCGAGCGTTGTCTCGTTTGGGACCTGGAT
GTACAAAAATGTATGTGCAATAAAGTGTGTGCCCATAAAGGGACACTTGGGAAGG

hide sequence

RefSeq Acc Id:

XM_008763999 ⟹ XP_008762221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	133,023,077 - 133,026,597 (-)	NCBI
Rnor_6.0	5	138,466,298 - 138,469,759 (-)	NCBI

Sequence:

show sequence

CCAGCGTGGGGTGACTACGGTGCAGATGGCGGAAATGGACCTGGTGGCTGAGTTGCCGCGTCCC
GAGGGTGCTGCGCGCTGGGCCGAGGCTCTTCTGCGATGTTTTACCTGGCCGCGGCAGTGTCAGA
TTTCTATATTCCTGTCTCTGAAATGCCTGAACACAAGATCCACTCATCTGGTGGCCCACTGCAG
ATAACAATGAAGATGGTGCCGAAGATGCTCTCTCCTCTGGTTAAGGACTGGGCTCCCAAAGCAT
TTATAGTTTCGTTCAAGCTGGAGACAGACCCGGACATCATCATTAGTCGGGCTCGGAATGCTCT
GGAAGTTTACCAGCATCAAGTAGTGGTGGCCAATATCCTGGAGTCAATAAAGTCCTTTGTGATT
ATTGTAACCAAAGACTCAGAGACAAAGTTACTGCTGTCTGAGGACGAGGTAGCAAGAGGCATGG
TGATAGAAGAGAAGATCGTAGACGACCTTCGGTCTCGACACACAGCGTTTATATGTGACAGAAA
CTGAAGGGATGCTCCCCTAGGGTTAAAAGCCGGGTTCTCACCACTGATGTGAACTAAAGTTAAT
CCTTTGTTAAGGATAAACACAGTGAAGAAGTGGCAAAAAACAGTGTGCGGGCAAAGGCCTGTGA
AACACTGGACACCTTGATCTGGAAAGTGAACAAGATTCACAAAGACTGTGTGATTGCGTGTTCT
GCAGAGCAGACGGGACTGGAGCTGCTGTCTGTCAGCCTGCTGTACAGTAGAAAGATCGTAGGCG
CATGAATGGTCATGCTCTGAAGAAGTACTTATCGAGTGCCTACCCTTTGCCAGGGCCTTTGTGC
GCTGTGAGGGTCTGAAAGATGAGCGAGCGTTGTCTCGTTTGGGACCTGGATGTACAAAAATGTA
TGTGCAATAAAGTGTGTGCCCATAAAGGGACACTTGGGAAGG

hide sequence

RefSeq Acc Id:

XR_005504406

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	133,023,077 - 133,026,603 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001034099	(Get FASTA)	NCBI Sequence Viewer
	XP_008762220	(Get FASTA)	NCBI Sequence Viewer
	XP_008762221	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99208	(Get FASTA)	NCBI Sequence Viewer
	EDL90112	(Get FASTA)	NCBI Sequence Viewer
	EDL90113	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011392
	ENSRNOP00000011392.4

RefSeq Acc Id:

NP_001034099 ⟸ NM_001039010

- UniProtKB:

D4A6X7 (UniProtKB/TrEMBL), A6JZP0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEMDLVAELPRPEGAARWAEVMARFAARLGEQGRRVVLVTSGGTKVPLEARAVRFLDNFSSGR
RGAASAEVFLAAGYGVLFLYRARSAFPYAHRFPPQAWLSALRPSGPAQSGKLSLEAEENALPGF
AAALQGYQEAAAAGTFLAVEFTTLADYLHLLQAAALALNPLGSSAMFYLAAAVSDFYIPVSEMP
EHKIHSSGGPLQITMKMVPKMLSPLVKDWAPKAFIVSFKLETDPDIIISRARNALEVYQHQVVV
ANILESIKSFVIIVTKDSETKLLLSEDEVARGMVIEEKIVDDLRSRHTAFICDRN

hide sequence

RefSeq Acc Id:	XP_008762220 ⟸ XM_008763998
- Peptide Label:	isoform X1
- UniProtKB:	A6JZP1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFYLAAAVSDFYIPVSEMPEHKIHSSGGPLQITMKMVPKMLSPLVKDWAPKAFIVSFKLETDPD IIISRARNALEVYQHQVVVANILESIKSFVIIVTKDSETKLLLSEDEVARGMVIEEKIVDDLRS RHTAFICDRN hide sequence

RefSeq Acc Id:	XP_008762221 ⟸ XM_008763999
- Peptide Label:	isoform X1
- UniProtKB:	A6JZP1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFYLAAAVSDFYIPVSEMPEHKIHSSGGPLQITMKMVPKMLSPLVKDWAPKAFIVSFKLETDPD IIISRARNALEVYQHQVVVANILESIKSFVIIVTKDSETKLLLSEDEVARGMVIEEKIVDDLRS RHTAFICDRN hide sequence

RefSeq Acc Id:

ENSRNOP00000011392 ⟸ ENSRNOT00000011392

Protein Domains

DNA/pantothenate metabolism flavoprotein C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A6X7-F1-model_v2	AlphaFold	D4A6X7	1-311	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693981

Promoter ID:

EPDNEW_R4506

Type:

single initiation site

Name:

Ppcs_1

Description:

phosphopantothenoylcysteine synthetase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	138,470,099 - 138,470,159	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311399	AgrOrtholog
BioCyc Gene	G2FUF-40087	BioCyc
BioCyc Pathway	PWY-7850 [taurine biosynthesis II]	BioCyc
	PWY-7851 [coenzyme A biosynthesis II (eukaryotic)]	BioCyc
Ensembl Genes	ENSRNOG00000008572	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011392	ENTREZGENE
	ENSRNOT00000011392.7	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.10300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7384489	IMAGE-MGC_LOAD
InterPro	CoaB-like_sf	UniProtKB/TrEMBL
	DNA/pantothenate-metab_flavo_C	UniProtKB/TrEMBL
KEGG Report	rno:298490	UniProtKB/TrEMBL
MGC_CLONE	MGC:116383	IMAGE-MGC_LOAD
NCBI Gene	298490	ENTREZGENE
PANTHER	CORNICHON-RELATED	UniProtKB/TrEMBL
	PHOSPHOPANTOTHENATE--CYSTEINE LIGASE	UniProtKB/TrEMBL
Pfam	DFP	UniProtKB/TrEMBL
PhenoGen	Ppcs	PhenoGen
RatGTEx	ENSRNOG00000008572	RatGTEx
Superfamily-SCOP	DNA/pantothenate-metab_flavo_C	UniProtKB/TrEMBL
UniProt	A6JZP0	ENTREZGENE, UniProtKB/TrEMBL
	A6JZP1	ENTREZGENE, UniProtKB/TrEMBL
	D4A6X7	ENTREZGENE, UniProtKB/TrEMBL
	Q4KLH2_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Ppcs	phosphopantothenoylcysteine synthetase	RGD1311399	similar to RIKEN cDNA 6330579B17 gene	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1311399	similar to RIKEN cDNA 6330579B17 gene	RGD1311399_predicted	similar to RIKEN cDNA 6330579B17 gene (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1311399_predicted	similar to RIKEN cDNA 6330579B17 gene (predicted)	LOC298490_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC298490_predicted	similar to RIKEN cDNA 6330579B17 gene (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)