Ptpru (protein tyrosine phosphatase, receptor type, U) - Rat Genome Database

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Gene: Ptpru (protein tyrosine phosphatase, receptor type, U) Rattus norvegicus
Analyze
Symbol: Ptpru
Name: protein tyrosine phosphatase, receptor type, U
RGD ID: 620782
Description: Predicted to enable beta-catenin binding activity and protein tyrosine phosphatase activity. Involved in animal organ regeneration and response to glucocorticoid. Predicted to be located in cell-cell junction. Biomarker of membranous glomerulonephritis and nephrosis. Orthologous to human PTPRU (protein tyrosine phosphatase receptor type U); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: R-ptp-psi; receptor-type tyrosine-protein phosphatase U
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25143,950,542 - 144,024,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5143,950,965 - 144,024,768 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5146,656,411 - 146,730,321 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05148,426,261 - 148,500,169 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05148,413,833 - 148,488,044 (-)NCBIRnor_WKY
Rnor_6.05149,922,374 - 149,996,352 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5149,922,352 - 149,996,334 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05153,601,160 - 153,675,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45150,612,095 - 150,695,183 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15150,660,034 - 150,668,570 (-)NCBI
Celera5142,397,414 - 142,468,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Early changes in gene expression that influence the course of primary glomerular disease. Clement LC, etal., Kidney Int. 2007 Aug;72(3):337-47. Epub 2007 Apr 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Gene expressions of protein tyrosine phosphatases in regenerating rat liver and rat ascites hepatoma cells. Kitamura T, etal., Jpn J Cancer Res. 1995 Sep;86(9):811-8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment. Siu B, etal., BMC Nephrol. 2006 Mar 15;7:6.
11. RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system. Sommer L, etal., Dev Dyn 1997 Jan;208(1):48-61.
12. Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate. Wharram BL, etal., J Clin Invest. 2000 Nov;106(10):1281-90.
Additional References at PubMed
PMID:9054423   PMID:12501215   PMID:15978577   PMID:16574648  


Genomics

Comparative Map Data
Ptpru
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25143,950,542 - 144,024,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5143,950,965 - 144,024,768 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5146,656,411 - 146,730,321 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05148,426,261 - 148,500,169 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05148,413,833 - 148,488,044 (-)NCBIRnor_WKY
Rnor_6.05149,922,374 - 149,996,352 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5149,922,352 - 149,996,334 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05153,601,160 - 153,675,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45150,612,095 - 150,695,183 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15150,660,034 - 150,668,570 (-)NCBI
Celera5142,397,414 - 142,468,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
PTPRU
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38129,236,522 - 29,326,800 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl129,236,516 - 29,326,813 (+)EnsemblGRCh38hg38GRCh38
GRCh37129,563,034 - 29,653,312 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,435,634 - 29,525,903 (+)NCBINCBI36Build 36hg18NCBI36
Build 34129,383,643 - 29,473,927NCBI
Celera127,959,180 - 28,049,910 (+)NCBICelera
Cytogenetic Map1p35.3NCBI
HuRef127,814,346 - 27,905,164 (+)NCBIHuRef
CHM1_1129,678,424 - 29,768,677 (+)NCBICHM1_1
T2T-CHM13v2.0129,079,179 - 29,169,454 (+)NCBIT2T-CHM13v2.0
Ptpru
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394131,495,768 - 131,565,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4131,495,768 - 131,565,599 (-)EnsemblGRCm39 Ensembl
GRCm384131,768,457 - 131,838,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4131,768,457 - 131,838,288 (-)EnsemblGRCm38mm10GRCm38
MGSCv374131,324,372 - 131,394,193 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364131,040,533 - 131,110,354 (-)NCBIMGSCv36mm8
Celera4129,928,568 - 129,998,810 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map464.5NCBI
Ptpru
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554528,223,692 - 8,296,769 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554528,223,773 - 8,296,769 (+)NCBIChiLan1.0ChiLan1.0
PTPRU
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1129,556,675 - 29,623,247 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,551,912 - 29,622,104 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0128,507,078 - 28,597,154 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PTPRU
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,284,979 - 71,363,253 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,285,851 - 71,363,691 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,861,226 - 67,939,839 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,844,918 - 71,923,499 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,844,933 - 71,923,492 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,673,740 - 68,752,383 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0269,681,824 - 69,760,389 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0270,679,504 - 70,758,203 (-)NCBIUU_Cfam_GSD_1.0
Ptpru
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505847,268,246 - 47,438,405 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647413,197,786 - 13,263,362 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647413,197,786 - 13,263,187 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRU
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl686,137,737 - 86,228,145 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1686,137,743 - 86,228,148 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2680,024,234 - 80,106,252 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRU
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120103,497,681 - 103,586,494 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20103,498,839 - 103,586,348 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603312,943,572 - 13,032,266 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpru
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,994,521 - 13,073,251 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,994,562 - 13,072,723 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpru
544 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:84
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000036148
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat

Markers in Region
AW535311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,026,523 - 144,026,691 (+)MAPPERmRatBN7.2
Rnor_6.05149,998,090 - 149,998,257NCBIRnor6.0
Rnor_5.05153,677,269 - 153,677,436UniSTSRnor5.0
RGSC_v3.45150,696,939 - 150,697,106UniSTSRGSC3.4
Celera5142,470,527 - 142,470,694UniSTS
RH 3.4 Map5988.5UniSTS
Cytogenetic Map5q36UniSTS
RH134910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25143,950,703 - 143,950,905 (+)MAPPERmRatBN7.2
Rnor_6.05149,922,536 - 149,922,737NCBIRnor6.0
Rnor_5.05153,601,322 - 153,601,523UniSTSRnor5.0
RGSC_v3.45150,611,834 - 150,612,035UniSTSRGSC3.4
Celera5142,397,153 - 142,397,354UniSTS
RH 3.4 Map5964.7UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 64 1 12 1
Low 3 32 43 27 19 27 1 1 10 34 28 10 1
Below cutoff 11 14 14 14 7 10 1 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000036148   ⟹   ENSRNOP00000030956
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5143,950,965 - 144,024,768 (-)Ensembl
Rnor_6.0 Ensembl5149,922,797 - 149,996,334 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091637   ⟹   ENSRNOP00000072635
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5143,950,965 - 144,020,870 (-)Ensembl
Rnor_6.0 Ensembl5149,922,352 - 149,987,910 (-)Ensembl
RefSeq Acc Id: NM_001191575   ⟹   NP_001178504
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,965 - 144,024,768 (-)NCBI
Rnor_6.05149,922,797 - 149,996,334 (-)NCBI
Rnor_5.05153,601,160 - 153,675,514 (-)NCBI
Celera5142,397,414 - 142,468,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238997   ⟹   XP_006239059
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,788 (-)NCBI
Rnor_6.05149,922,374 - 149,996,350 (-)NCBI
Rnor_5.05153,601,160 - 153,675,514 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238998   ⟹   XP_006239060
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,788 (-)NCBI
Rnor_6.05149,922,374 - 149,996,350 (-)NCBI
Rnor_5.05153,601,160 - 153,675,514 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764130   ⟹   XP_008762352
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,981,669 - 144,024,791 (-)NCBI
Rnor_6.05149,953,604 - 149,996,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593120   ⟹   XP_017448609
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,789 (-)NCBI
Rnor_6.05149,922,374 - 149,996,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593121   ⟹   XP_017448610
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,789 (-)NCBI
Rnor_6.05149,922,374 - 149,996,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593122   ⟹   XP_017448611
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,788 (-)NCBI
Rnor_6.05149,922,374 - 149,996,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109154   ⟹   XP_038965082
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,020,758 (-)NCBI
RefSeq Acc Id: XM_039109155   ⟹   XP_038965083
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,789 (-)NCBI
RefSeq Acc Id: XM_039109156   ⟹   XP_038965084
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,024,789 (-)NCBI
RefSeq Acc Id: XM_039109157   ⟹   XP_038965085
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25143,950,542 - 144,020,758 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001178504   ⟸   NM_001191575
- Peptide Label: precursor
- UniProtKB: F1MAG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239060   ⟸   XM_006238998
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006239059   ⟸   XM_006238997
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008762352   ⟸   XM_008764130
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017448610   ⟸   XM_017593121
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448611   ⟸   XM_017593122
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017448609   ⟸   XM_017593120
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000030956   ⟸   ENSRNOT00000036148
RefSeq Acc Id: ENSRNOP00000072635   ⟸   ENSRNOT00000091637
RefSeq Acc Id: XP_038965083   ⟸   XM_039109155
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965084   ⟸   XM_039109156
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038965082   ⟸   XM_039109154
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038965085   ⟸   XM_039109157
- Peptide Label: isoform X9
Protein Domains
Fibronectin type-III   MAM   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1MAG7-F1-model_v2 AlphaFold F1MAG7 1-1446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694088
Promoter ID:EPDNEW_R4612
Type:single initiation site
Name:Ptpru_1
Description:protein tyrosine phosphatase, receptor type, U
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05149,996,320 - 149,996,380EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620782 AgrOrtholog
BioCyc Gene G2FUF-39721 BioCyc
Ensembl Genes ENSRNOG00000013515 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030956 ENTREZGENE
  ENSRNOP00000030956.4 UniProtKB/TrEMBL
  ENSRNOP00000072635 ENTREZGENE
  ENSRNOP00000072635.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036148 ENTREZGENE
  ENSRNOT00000036148.5 UniProtKB/TrEMBL
  ENSRNOT00000091637 ENTREZGENE
  ENSRNOT00000091637.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ConA-like_dom UniProtKB/TrEMBL
  Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr/Dual-sp_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
KEGG Report rno:116680 UniProtKB/TrEMBL
NCBI Gene 116680 ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE-RELATED UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptpru PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
  MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2K3H0_RAT UniProtKB/TrEMBL
  F1MAG7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ptpru  protein tyrosine phosphatase, receptor type, U      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ptpru  protein tyrosine phosphatase, receptor type, U      Symbol and Name status set to provisional 70820 PROVISIONAL