Ptprc (protein tyrosine phosphatase, receptor type, C) - Rat Genome Database

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Gene: Ptprc (protein tyrosine phosphatase, receptor type, C) Rattus norvegicus
Analyze
Symbol: Ptprc
Name: protein tyrosine phosphatase, receptor type, C
RGD ID: 3451
Description: Enables protein tyrosine phosphatase activity. Involved in several processes, including T cell receptor signaling pathway; response to aldosterone; and response to gamma radiation. Located in cell surface and plasma membrane. Biomarker of hypertension and retinal degeneration. Human ortholog(s) of this gene implicated in multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency 105. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; primary immunodeficiency pathway; T cell receptor signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD45; L-CA; Lca; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; Protein tyrosine phosphatase, receptor-type, c polypeptide; receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   BBDP.WF-(D13Rat124-D13Mgh5)/Sunn   BBDP.BBDR-Gimap5, WF-(D13Rat124-D13Mgh5)/Sunn  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81352,147,717 - 52,259,810 (-)NCBIGRCr8
mRatBN7.21349,596,193 - 49,708,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1349,596,193 - 49,708,692 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1352,203,850 - 52,315,661 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01353,491,734 - 53,603,549 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01350,758,824 - 50,870,643 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01355,061,561 - 55,174,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01360,094,038 - 60,205,773 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41351,246,163 - 51,357,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11351,261,097 - 51,309,893 (-)NCBI
Celera1349,881,478 - 49,993,142 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-acetamidofluorene  (EXP)
2-butoxyethanol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allyl methyl disulfide  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
beauvericin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
Calcimycin  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorotoluron  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cordycepin  (ISO)
Cuprizon  (EXP)
cyclizine  (ISO)
cyclophosphamide  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP)
diquat  (ISO)
enniatin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
histamine  (ISO)
isotretinoin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pirinixic acid  (EXP,ISO)
prednisone  (ISO)
silicon dioxide  (EXP,ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
succimer  (ISO)
T-2 toxin  (ISO)
tamibarotene  (ISO)
tebuconazole  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetrathiomolybdate(2-)  (ISO)
Thiamet G  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
triprolidine  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
tungsten  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-beta T cell proliferation  (ISO)
B cell differentiation  (ISO)
B cell proliferation  (ISO,ISS)
B cell receptor signaling pathway  (ISO,ISS)
bone marrow development  (IEA,ISO)
cell cycle phase transition  (IEA,ISO)
defense response to virus  (ISO,ISS)
dephosphorylation  (ISO,ISS)
extrinsic apoptotic signaling pathway  (ISO)
gamma-delta T cell differentiation  (ISO)
hematopoietic progenitor cell differentiation  (IEA,ISO)
heterotypic cell-cell adhesion  (ISO)
leukocyte cell-cell adhesion  (ISO)
MAPK cascade  (ISO)
natural killer cell differentiation  (ISO)
negative regulation of cell adhesion involved in substrate-bound cell migration  (IEA,ISO)
negative regulation of cytokine-mediated signaling pathway  (ISO,ISS)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of interleukin-4-mediated signaling pathway  (IEA,ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of protein autophosphorylation  (ISO)
negative regulation of protein kinase activity  (ISO,ISS)
negative regulation of receptor signaling pathway via JAK-STAT  (IEA,ISO)
negative regulation of T cell mediated cytotoxicity  (ISO,ISS)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
negative thymic T cell selection  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
plasma membrane raft distribution  (ISO)
positive regulation of alpha-beta T cell proliferation  (ISO)
positive regulation of antigen receptor-mediated signaling pathway  (ISO,ISS)
positive regulation of B cell proliferation  (IEA,ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (ISO)
positive regulation of Fc receptor mediated stimulatory signaling pathway  (ISO)
positive regulation of gamma-delta T cell differentiation  (ISO)
positive regulation of hematopoietic stem cell migration  (IEA,ISO)
positive regulation of humoral immune response mediated by circulating immunoglobulin  (ISO)
positive regulation of immunoglobulin production  (IEA,ISO)
positive regulation of interleukin-2 production  (ISO)
positive regulation of isotype switching to IgG isotypes  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of stem cell proliferation  (IEA,ISO)
positive regulation of T cell differentiation  (ISO)
positive regulation of T cell mediated cytotoxicity  (ISO)
positive regulation of T cell mediated immunity  (ISO)
positive regulation of T cell proliferation  (ISO,ISS)
positive regulation of tumor necrosis factor production  (ISO)
positive thymic T cell selection  (ISO)
protein autophosphorylation  (ISO)
protein dephosphorylation  (ISO,ISS,TAS)
regulation of cell cycle  (ISO,ISS)
regulation of extrinsic apoptotic signaling pathway  (ISO)
regulation of gene expression  (IGI,ISO)
regulation of humoral immune response mediated by circulating immunoglobulin  (ISO)
regulation of interleukin-8 production  (IEA,ISO)
regulation of phagocytosis  (IEA,ISO)
regulation of T cell receptor signaling pathway  (ISO)
release of sequestered calcium ion into cytosol  (ISO,ISS)
response to aldosterone  (IEP)
response to gamma radiation  (IDA)
signal transduction  (IBA)
stem cell development  (IEA,ISO)
T cell differentiation  (ISO,ISS)
T cell proliferation  (ISO)
T cell receptor signaling pathway  (IEA,IGI,ISO,ISS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus. Barclay AN, etal., EMBO J 1987 May;6(5):1259-64.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling. Irles C, etal., Nat Immunol 2003 Feb;4(2):189-97. Epub 2002 Dec 23.
5. A point mutation in PTPRC is associated with the development of multiple sclerosis. Jacobsen M, etal., Nat Genet 2000 Dec;26(4):495-9.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Ukrainskii biokhimicheskii zhurnal NO_AUTHOR Ukr Biokhim Zh. 2006 Sep-Oct;78(5):127-31.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Gene expression changes in the retina after systemic administration of aldosterone. Ono A, etal., Jpn J Ophthalmol. 2018 Jul;62(4):499-507. doi: 10.1007/s10384-018-0595-4. Epub 2018 Apr 30.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Molecular basis of antigenic differences between the RT7 alleles of rat CD45. Symons A and Barclay AN, Immunogenetics 2000 Jul;51(8-9):747-50.
16. Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1. Symons A, etal., Glycobiology. 2000 Jun;10(6):559-63.
17. A deletion in the gene encoding the CD45 antigen in a patient with SCID. Tchilian EZ, etal., J Immunol. 2001 Jan 15;166(2):1308-13.
18. Evidence from cDNA clones that the rat leukocyte-common antigen (T200) spans the lipid bilayer and contains a cytoplasmic domain of 80,000 Mr. Thomas ML, etal., Cell 1985 May;41(1):83-93.
19. The role of KCa3.1 channels in cardiac fibrosis induced by pressure overload in rats. Zhao LM, etal., Pflugers Arch. 2015 Nov;467(11):2275-85. doi: 10.1007/s00424-015-1694-4. Epub 2015 Feb 27.
20. Administration of recombinant P-selectin glycoprotein ligand Fc fusion protein suppresses inflammation and neointimal formation in Zucker diabetic rat model. Zhou Z, etal., Arterioscler Thromb Vasc Biol 2002 Oct 1;22(10):1598-603.
Additional References at PubMed
PMID:61878   PMID:1378817   PMID:1793833   PMID:2853967   PMID:6233370   PMID:6610701   PMID:7477352   PMID:7477353   PMID:7499277   PMID:7589135   PMID:7630421   PMID:7688139  
PMID:7743522   PMID:7751624   PMID:7807014   PMID:8041705   PMID:8043862   PMID:8175795   PMID:8334701   PMID:8552190   PMID:8566025   PMID:8566034   PMID:8666928   PMID:8692271  
PMID:8788039   PMID:8889548   PMID:9015183   PMID:9197241   PMID:9208839   PMID:9254656   PMID:9725213   PMID:10358156   PMID:10508267   PMID:10848813   PMID:10943842   PMID:10970857  
PMID:11201744   PMID:11466198   PMID:12100025   PMID:12115612   PMID:12354383   PMID:12519789   PMID:12574355   PMID:12714519   PMID:12900455   PMID:12902479   PMID:14609575   PMID:14625311  
PMID:14990792   PMID:15128768   PMID:15240667   PMID:15557316   PMID:15599401   PMID:15661907   PMID:15795238   PMID:15843532   PMID:15845452   PMID:15909309   PMID:15978577   PMID:16263122  
PMID:16287714   PMID:16455951   PMID:16493007   PMID:17213291   PMID:17277142   PMID:17941951   PMID:18249142   PMID:18628982   PMID:18762567   PMID:19015308   PMID:19838199   PMID:19861679  
PMID:19934022   PMID:19946888   PMID:20458337   PMID:20660734   PMID:20709950   PMID:21166153   PMID:21460847   PMID:21606356   PMID:21911094   PMID:22072979   PMID:22871113   PMID:24029230  
PMID:24337748   PMID:25074919  


Genomics

Comparative Map Data
Ptprc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81352,147,717 - 52,259,810 (-)NCBIGRCr8
mRatBN7.21349,596,193 - 49,708,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1349,596,193 - 49,708,692 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1352,203,850 - 52,315,661 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01353,491,734 - 53,603,549 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01350,758,824 - 50,870,643 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01355,061,561 - 55,174,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01360,094,038 - 60,205,773 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41351,246,163 - 51,357,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11351,261,097 - 51,309,893 (-)NCBI
Celera1349,881,478 - 49,993,142 (-)NCBICelera
Cytogenetic Map13q13NCBI
PTPRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381198,638,713 - 198,757,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1198,638,457 - 198,759,342 (+)EnsemblGRCh38hg38GRCh38
GRCh371198,608,170 - 198,726,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361196,874,760 - 196,993,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 341195,339,881 - 195,393,989NCBI
Celera1171,730,687 - 171,849,073 (+)NCBICelera
Cytogenetic Map1q31.3-q32.1NCBI
HuRef1169,775,326 - 169,893,838 (+)NCBIHuRef
CHM1_11200,030,413 - 200,148,903 (+)NCBICHM1_1
T2T-CHM13v2.01197,898,421 - 198,017,392 (+)NCBIT2T-CHM13v2.0
Ptprc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391137,990,601 - 138,103,491 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1137,990,599 - 138,103,446 (-)EnsemblGRCm39 Ensembl
GRCm381138,062,859 - 138,175,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1138,062,861 - 138,175,708 (-)EnsemblGRCm38mm10GRCm38
MGSCv371139,959,438 - 140,071,882 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361139,879,826 - 139,991,677 (-)NCBIMGSCv36mm8
Celera1140,702,480 - 140,816,534 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.73NCBI
Ptprc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540635,005,214 - 35,129,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540635,005,577 - 35,127,395 (+)NCBIChiLan1.0ChiLan1.0
PTPRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2150,619,001 - 50,737,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1150,578,414 - 50,696,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01174,246,389 - 174,364,893 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11178,555,803 - 178,674,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1178,556,104 - 178,672,994 (+)Ensemblpanpan1.1panPan2
PTPRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.174,155,876 - 4,282,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.073,809,638 - 3,848,816 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.073,851,043 - 3,967,973 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl73,809,641 - 3,967,858 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBIUU_Cfam_GSD_1.0
Ptprc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934476,032,103 - 76,143,785 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365675,267,615 - 5,378,258 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365675,266,653 - 5,378,464 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1021,560,073 - 21,601,308 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11021,482,984 - 21,601,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21026,308,772 - 26,332,086 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103230364
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12530,655,014 - 30,777,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2530,653,044 - 30,777,303 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605531,544,354 - 31,666,237 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247981,699,541 - 1,814,656 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247981,700,732 - 1,814,603 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptprc
1098 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1446
Count of miRNA genes:245
Interacting mature miRNAs:309
Transcripts:ENSRNOT00000000814, ENSRNOT00000029865, ENSRNOT00000029878, ENSRNOT00000060292, ENSRNOT00000064785
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134372077062022792Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat

Markers in Region
D13Mit7  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13q13UniSTS
D13Got34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21349,709,060 - 49,709,222 (+)MAPPERmRatBN7.2
Rnor_6.01355,174,550 - 55,174,711NCBIRnor6.0
Rnor_5.01360,206,196 - 60,206,357UniSTSRnor5.0
RGSC_v3.41351,358,852 - 51,359,014RGDRGSC3.4
RGSC_v3.41351,358,853 - 51,359,014UniSTSRGSC3.4
RGSC_v3.11351,372,932 - 51,373,094RGD
Celera1349,994,000 - 49,994,161UniSTS
Cytogenetic Map13q13UniSTS
RH94594  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21349,597,057 - 49,597,218 (+)MAPPERmRatBN7.2
Rnor_6.01355,062,426 - 55,062,586NCBIRnor6.0
Rnor_5.01360,094,903 - 60,095,063UniSTSRnor5.0
RGSC_v3.41351,247,028 - 51,247,188UniSTSRGSC3.4
Celera1349,882,343 - 49,882,503UniSTS
Cytogenetic Map13q13UniSTS
RH142448  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13q13UniSTS
RH136913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21349,596,193 - 49,596,344 (+)MAPPERmRatBN7.2
Rnor_6.01355,061,562 - 55,061,712NCBIRnor6.0
Rnor_5.01360,094,039 - 60,094,189UniSTSRnor5.0
RGSC_v3.41351,246,164 - 51,246,314UniSTSRGSC3.4
Celera1349,881,479 - 49,881,629UniSTS
Cytogenetic Map13q13UniSTS


Related Rat Strains
The following Strains have been annotated to Ptprc
BBDP.BBDR-Gimap5, WF-(D13Rat124-D13Mgh5)/Sunn     BBDP.WF-(D13Rat124-D13Mgh5)/Sunn    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF251010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF288130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF556033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA508247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB788988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK364357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN541893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV080346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M25820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M25821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M25822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M25823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S40716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000814   ⟹   ENSRNOP00000000814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1349,596,193 - 49,708,692 (-)Ensembl
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000029865   ⟹   ENSRNOP00000029889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1349,596,193 - 49,708,218 (-)Ensembl
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000029878   ⟹   ENSRNOP00000030503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1349,596,193 - 49,708,218 (-)Ensembl
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000060292   ⟹   ENSRNOP00000057042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1349,596,193 - 49,708,218 (-)Ensembl
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000064785   ⟹   ENSRNOP00000063859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1349,596,193 - 49,708,218 (-)Ensembl
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)Ensembl
RefSeq Acc Id: NM_001109887   ⟹   NP_001103357
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,746 (-)NCBI
mRatBN7.21349,596,193 - 49,708,218 (-)NCBI
Rnor_6.01355,061,561 - 55,173,692 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
RGSC_v3.41351,246,163 - 51,357,995 (-)RGD
Celera1349,881,478 - 49,993,142 (-)RGD
Sequence:
RefSeq Acc Id: NM_001109888   ⟹   NP_001103358
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,746 (-)NCBI
mRatBN7.21349,596,193 - 49,708,218 (-)NCBI
Rnor_6.01355,061,561 - 55,173,692 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
RGSC_v3.41351,246,163 - 51,357,995 (-)RGD
Celera1349,881,478 - 49,993,142 (-)RGD
Sequence:
RefSeq Acc Id: NM_001109889   ⟹   NP_001103359
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,746 (-)NCBI
mRatBN7.21349,596,193 - 49,708,218 (-)NCBI
Rnor_6.01355,061,561 - 55,173,692 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
RGSC_v3.41351,246,163 - 51,357,995 (-)RGD
Celera1349,881,478 - 49,993,142 (-)RGD
Sequence:
RefSeq Acc Id: NM_001109890   ⟹   NP_001103360
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,746 (-)NCBI
mRatBN7.21349,596,193 - 49,708,218 (-)NCBI
Rnor_6.01355,061,561 - 55,173,692 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
RGSC_v3.41351,246,163 - 51,357,995 (-)RGD
Celera1349,881,478 - 49,993,142 (-)RGD
Sequence:
RefSeq Acc Id: NM_138507   ⟹   NP_612516
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,746 (-)NCBI
mRatBN7.21349,596,193 - 49,708,218 (-)NCBI
Rnor_6.01355,061,561 - 55,173,692 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
RGSC_v3.41351,246,163 - 51,357,995 (-)RGD
Celera1349,881,478 - 49,993,142 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249912   ⟹   XP_006249974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,810 (-)NCBI
mRatBN7.21349,596,193 - 49,708,282 (-)NCBI
Rnor_6.01355,061,561 - 55,173,744 (-)NCBI
Rnor_5.01360,094,038 - 60,205,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769534   ⟹   XP_008767756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,810 (-)NCBI
mRatBN7.21349,596,193 - 49,708,282 (-)NCBI
Rnor_6.01355,061,561 - 55,173,744 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090347   ⟹   XP_038946275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81352,147,717 - 52,259,810 (-)NCBI
mRatBN7.21349,596,193 - 49,708,282 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001103357 (Get FASTA)   NCBI Sequence Viewer  
  NP_001103358 (Get FASTA)   NCBI Sequence Viewer  
  NP_001103359 (Get FASTA)   NCBI Sequence Viewer  
  NP_001103360 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416423 (Get FASTA)   NCBI Sequence Viewer  
  NP_612516 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249974 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767756 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946275 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41513 (Get FASTA)   NCBI Sequence Viewer  
  AAA41515 (Get FASTA)   NCBI Sequence Viewer  
  AAA41516 (Get FASTA)   NCBI Sequence Viewer  
  AAA41517 (Get FASTA)   NCBI Sequence Viewer  
  AAA41518 (Get FASTA)   NCBI Sequence Viewer  
  AAA41519 (Get FASTA)   NCBI Sequence Viewer  
  AAA41520 (Get FASTA)   NCBI Sequence Viewer  
  AAA41521 (Get FASTA)   NCBI Sequence Viewer  
  AAB22648 (Get FASTA)   NCBI Sequence Viewer  
  AAF72179 (Get FASTA)   NCBI Sequence Viewer  
  CAA68272 (Get FASTA)   NCBI Sequence Viewer  
  CAA68273 (Get FASTA)   NCBI Sequence Viewer  
  CAA68274 (Get FASTA)   NCBI Sequence Viewer  
  CAA68275 (Get FASTA)   NCBI Sequence Viewer  
  EDM09643 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000814
  ENSRNOP00000030503
  ENSRNOP00000057042
  ENSRNOP00000057042.2
  ENSRNOP00000063859
  ENSRNOP00000063859.1
  ENSRNOP00000100800
  ENSRNOP00000110329
GenBank Protein P04157 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_612516   ⟸   NM_138507
- Peptide Label: isoform 4 precursor
- UniProtKB: P04157 (UniProtKB/Swiss-Prot),   A0A8L2QFX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103357   ⟸   NM_001109887
- Peptide Label: isoform 3 precursor
- UniProtKB: A6ICK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103358   ⟸   NM_001109888
- Peptide Label: isoform 5 precursor
- UniProtKB: A0A8L2PZM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103359   ⟸   NM_001109889
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A8L2PZM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103360   ⟸   NM_001109890
- Peptide Label: isoform 1 precursor
- UniProtKB: A6ICK0 (UniProtKB/TrEMBL),   A6ICK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249974   ⟸   XM_006249912
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767756   ⟸   XM_008769534
- Peptide Label: isoform X1
- UniProtKB: A6ICK1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000814   ⟸   ENSRNOT00000000814
Ensembl Acc Id: ENSRNOP00000057042   ⟸   ENSRNOT00000060292
Ensembl Acc Id: ENSRNOP00000029889   ⟸   ENSRNOT00000029865
Ensembl Acc Id: ENSRNOP00000030503   ⟸   ENSRNOT00000029878
Ensembl Acc Id: ENSRNOP00000063859   ⟸   ENSRNOT00000064785
RefSeq Acc Id: XP_038946275   ⟸   XM_039090347
- Peptide Label: isoform X3
- UniProtKB: A6ICK1 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04157-F1-model_v2 AlphaFold P04157 1-1273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698859
Promoter ID:EPDNEW_R9384
Type:initiation region
Name:Ptprc_1
Description:protein tyrosine phosphatase, receptor type, C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01355,173,661 - 55,173,721EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3451 AgrOrtholog
BioCyc Gene G2FUF-18111 BioCyc
Ensembl Genes ENSRNOG00000000655 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000814 ENTREZGENE
  ENSRNOT00000029878 ENTREZGENE
  ENSRNOT00000060292 ENTREZGENE
  ENSRNOT00000060292.5 UniProtKB/Swiss-Prot
  ENSRNOT00000064785 ENTREZGENE
  ENSRNOT00000064785.4 UniProtKB/Swiss-Prot
  ENSRNOT00000149921 ENTREZGENE
  ENSRNOT00000160765 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.90.190.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot
  Protein-Tyr_Phosphatase UniProtKB/Swiss-Prot
  PTP_recept_N UniProtKB/Swiss-Prot
  PTPase_domain UniProtKB/Swiss-Prot
  Ptprc UniProtKB/Swiss-Prot
  Tyr_Pase_AS UniProtKB/Swiss-Prot
  Tyr_Pase_cat UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot
KEGG Report rno:24699 UniProtKB/Swiss-Prot
NCBI Gene 24699 ENTREZGENE
PANTHER RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C UniProtKB/Swiss-Prot
Pfam CD45 UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  PTP_N UniProtKB/Swiss-Prot
  Y_phosphatase UniProtKB/Swiss-Prot
PharmGKB PTPRC RGD
PhenoGen Ptprc PhenoGen
PIRSF Leukocyte_common_antigen UniProtKB/Swiss-Prot
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot
PROSITE FN3 UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000000655 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
  PTPc UniProtKB/Swiss-Prot
  PTPc_motif UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot
  SSF52799 UniProtKB/Swiss-Prot
UniProt A0A8L2PZM8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QFX7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QGD4 ENTREZGENE, UniProtKB/TrEMBL
  A6ICK0 ENTREZGENE, UniProtKB/TrEMBL
  A6ICK1 ENTREZGENE, UniProtKB/TrEMBL
  A6ICK2 ENTREZGENE, UniProtKB/TrEMBL
  P04157 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ptprc  Protein tyrosine phosphatase, receptor-type, c polypeptide (antigen Cd45, leukocyte-common antigen/T200 glycoprotein) also RT7      Symbol and Name status set to approved 70586 APPROVED