PTPRC (protein tyrosine phosphatase receptor type C) - Rat Genome Database

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Gene: PTPRC (protein tyrosine phosphatase receptor type C) Canis lupus familiaris
Analyze
Symbol: PTPRC
Name: protein tyrosine phosphatase receptor type C
RGD ID: 12185434
Description: ENCODES a protein that exhibits ankyrin binding (ortholog); heparan sulfate proteoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN B cell differentiation (ortholog); B cell proliferation (ortholog); B cell receptor signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Gastro-Enteropancreatic Neuroendocrine Tumor (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN bleb (ortholog); cell periphery (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: CD45; CD45 antigen; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.174,155,876 - 4,282,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
ROS_Cfam_1.073,809,638 - 3,848,816 (-)NCBI
ROS_Cfam_1.073,851,043 - 3,967,973 (-)NCBI
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell differentiation  (ISO)
B cell proliferation  (ISO)
B cell receptor signaling pathway  (ISO)
bone marrow development  (ISO)
calcium-mediated signaling using intracellular calcium source  (ISO)
cell cycle phase transition  (ISO)
cellular response to extracellular stimulus  (ISO)
defense response to virus  (ISO)
dephosphorylation  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
heterotypic cell-cell adhesion  (ISO)
leukocyte cell-cell adhesion  (ISO)
natural killer cell differentiation  (ISO)
negative regulation of cell adhesion involved in substrate-bound cell migration  (ISO)
negative regulation of cytokine-mediated signaling pathway  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of protein autophosphorylation  (ISO)
negative regulation of protein kinase activity  (IBA)
negative regulation of protein tyrosine kinase activity  (ISO)
negative regulation of T cell mediated cytotoxicity  (ISO)
negative thymic T cell selection  (ISO)
peptidyl-tyrosine dephosphorylation  (IEA)
plasma membrane raft distribution  (ISO)
positive regulation of alpha-beta T cell proliferation  (ISO)
positive regulation of antigen receptor-mediated signaling pathway  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (ISO)
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis  (ISO)
positive regulation of gamma-delta T cell differentiation  (ISO)
positive regulation of hematopoietic stem cell migration  (ISO)
positive regulation of humoral immune response mediated by circulating immunoglobulin  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-2 production  (ISO)
positive regulation of isotype switching to IgG isotypes  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IBA)
positive regulation of protein tyrosine phosphatase activity  (ISO)
positive regulation of stem cell proliferation  (ISO)
positive regulation of T cell differentiation  (ISO)
positive regulation of T cell mediated cytotoxicity  (ISO)
positive regulation of T cell mediated immunity  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive thymic T cell selection  (ISO)
protein dephosphorylation  (IBA)
regulation of cell cycle  (ISO)
regulation of extrinsic apoptotic signaling pathway  (ISO)
regulation of gene expression  (ISO)
regulation of humoral immune response mediated by circulating immunoglobulin  (ISO)
regulation of interleukin-8 production  (ISO)
regulation of phagocytosis  (ISO)
regulation of protein tyrosine kinase activity  (ISO)
regulation of receptor signaling pathway via JAK-STAT  (ISO)
release of sequestered calcium ion into cytosol  (ISO)
response to gamma radiation  (ISO)
stem cell development  (ISO)
T cell differentiation  (ISO)
T cell proliferation  (ISO)
T cell receptor signaling pathway  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:24794330   PMID:26553299  


Genomics

Comparative Map Data
PTPRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.174,155,876 - 4,282,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
ROS_Cfam_1.073,809,638 - 3,848,816 (-)NCBI
ROS_Cfam_1.073,851,043 - 3,967,973 (-)NCBI
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
PTPRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1198,638,457 - 198,757,476 (+)EnsemblGRCh38hg38GRCh38
GRCh381198,639,025 - 198,757,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371198,608,170 - 198,726,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361196,874,760 - 196,993,168 (+)NCBINCBI36hg18NCBI36
Build 341195,339,881 - 195,393,989NCBI
Celera1171,730,687 - 171,849,073 (+)NCBI
Cytogenetic Map1q31.3-q32.1NCBI
HuRef1169,775,326 - 169,893,838 (+)NCBIHuRef
CHM1_11200,030,413 - 200,148,903 (+)NCBICHM1_1
Ptprc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391137,990,597 - 138,103,491 (-)NCBIGRCm39mm39
GRCm39 Ensembl1137,990,599 - 138,103,446 (-)Ensembl
GRCm381138,062,859 - 138,175,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1138,062,861 - 138,175,708 (-)EnsemblGRCm38mm10GRCm38
MGSCv371139,959,438 - 140,071,882 (-)NCBIGRCm37mm9NCBIm37
MGSCv361139,879,826 - 139,991,677 (-)NCBImm8
Celera1140,702,480 - 140,816,534 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.73NCBI
Ptprc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21349,596,193 - 49,708,283 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1349,596,193 - 49,708,692 (-)Ensembl
Rnor_6.01355,061,561 - 55,174,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01360,094,038 - 60,205,773 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41351,246,163 - 51,357,995 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11351,261,097 - 51,309,893 (-)NCBI
Celera1349,881,478 - 49,993,142 (-)NCBICelera
Cytogenetic Map13q13NCBI
Ptprc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540635,005,214 - 35,129,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540635,005,577 - 35,127,395 (+)NCBIChiLan1.0ChiLan1.0
PTPRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11178,555,803 - 178,674,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1178,556,104 - 178,672,994 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01174,246,389 - 174,364,893 (+)NCBIMhudiblu_PPA_v0panPan3
Ptprc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934476,032,103 - 76,143,785 (-)NCBI
SpeTri2.0NW_0049365675,266,653 - 5,378,464 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1021,466,373 - 21,764,560 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11021,482,984 - 21,601,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21026,308,772 - 26,332,086 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12530,655,014 - 30,777,367 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2530,653,044 - 30,777,303 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605531,544,354 - 31,666,237 (-)NCBIVero_WHO_p1.0
Ptprc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247981,700,732 - 1,814,603 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 4 4 6 4 4 5 3
Low 1 5 18 2 2 2 2 12 5 3
Below cutoff 4 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005622278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005622279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005622280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005622281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005622282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038606087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038606088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038606089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038606090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038606091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF434426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF434427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000017955   ⟹   ENSCAFP00000016627
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000017964   ⟹   ENSCAFP00000016636
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,282,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000060642   ⟹   ENSCAFP00000056086
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,282,038 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000064494   ⟹   ENSCAFP00000054863
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,282,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000067917   ⟹   ENSCAFP00000061006
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,282,038 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068442   ⟹   ENSCAFP00000060192
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,282,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080059   ⟹   ENSCAFP00000061730
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091845   ⟹   ENSCAFP00000054600
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl74,156,687 - 4,214,729 (-)Ensembl
RefSeq Acc Id: XM_005622278   ⟹   XP_005622335
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,155,876 - 4,282,151 (-)NCBI
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005622279   ⟹   XP_005622336
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,155,876 - 4,282,151 (-)NCBI
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005622280   ⟹   XP_005622337
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,155,876 - 4,282,151 (-)NCBI
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005622281   ⟹   XP_005622338
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,155,876 - 4,282,151 (-)NCBI
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005622282   ⟹   XP_005622339
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,155,876 - 4,282,151 (-)NCBI
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038480631   ⟹   XP_038336559
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
RefSeq Acc Id: XM_038480632   ⟹   XP_038336560
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
RefSeq Acc Id: XM_038480633   ⟹   XP_038336561
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
RefSeq Acc Id: XM_038480634   ⟹   XP_038336562
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
RefSeq Acc Id: XM_038480635   ⟹   XP_038336563
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBI
RefSeq Acc Id: XM_038541952   ⟹   XP_038397880
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
RefSeq Acc Id: XM_038541953   ⟹   XP_038397881
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
RefSeq Acc Id: XM_038541954   ⟹   XP_038397882
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
RefSeq Acc Id: XM_038541955   ⟹   XP_038397883
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
RefSeq Acc Id: XM_038541956   ⟹   XP_038397884
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBI
RefSeq Acc Id: XM_038606087   ⟹   XP_038462015
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
RefSeq Acc Id: XM_038606088   ⟹   XP_038462016
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
RefSeq Acc Id: XM_038606089   ⟹   XP_038462017
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
RefSeq Acc Id: XM_038606090   ⟹   XP_038462018
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
RefSeq Acc Id: XM_038606091   ⟹   XP_038462019
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBI
RefSeq Acc Id: XM_038670576   ⟹   XP_038526504
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.073,851,043 - 3,967,973 (-)NCBI
RefSeq Acc Id: XM_038670787   ⟹   XP_038526715
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.073,809,638 - 3,848,816 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005622339   ⟸   XM_005622282
- Peptide Label: isoform X22
- Sequence:
RefSeq Acc Id: XP_005622338   ⟸   XM_005622281
- Peptide Label: isoform X21
- Sequence:
RefSeq Acc Id: XP_005622337   ⟸   XM_005622280
- Peptide Label: isoform X20
- Sequence:
RefSeq Acc Id: XP_005622336   ⟸   XM_005622279
- Peptide Label: isoform X19
- Sequence:
RefSeq Acc Id: XP_005622335   ⟸   XM_005622278
- Peptide Label: isoform X18
- UniProtKB: F1Q1S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000054863   ⟸   ENSCAFT00000064494
RefSeq Acc Id: ENSCAFP00000056086   ⟸   ENSCAFT00000060642
RefSeq Acc Id: ENSCAFP00000061730   ⟸   ENSCAFT00000080059
RefSeq Acc Id: ENSCAFP00000061006   ⟸   ENSCAFT00000067917
RefSeq Acc Id: ENSCAFP00000060192   ⟸   ENSCAFT00000068442
RefSeq Acc Id: ENSCAFP00000054600   ⟸   ENSCAFT00000091845
RefSeq Acc Id: ENSCAFP00000016636   ⟸   ENSCAFT00000017964
RefSeq Acc Id: ENSCAFP00000016627   ⟸   ENSCAFT00000017955
RefSeq Acc Id: XP_038336563   ⟸   XM_038480635
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038336562   ⟸   XM_038480634
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038336561   ⟸   XM_038480633
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038336560   ⟸   XM_038480632
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038336559   ⟸   XM_038480631
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038462019   ⟸   XM_038606091
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038462018   ⟸   XM_038606090
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038462017   ⟸   XM_038606089
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038462016   ⟸   XM_038606088
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038462015   ⟸   XM_038606087
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038526715   ⟸   XM_038670787
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038526504   ⟸   XM_038670576
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038397884   ⟸   XM_038541956
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038397883   ⟸   XM_038541955
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038397882   ⟸   XM_038541954
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038397881   ⟸   XM_038541953
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038397880   ⟸   XM_038541952
- Peptide Label: isoform X13

Promoters
RGD ID:13683877
Promoter ID:EPDNEW_C1945
Type:initiation region
Name:PTPRC_1
Description:protein tyrosine phosphatase, receptor type C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.174,282,067 - 4,282,127EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 4156854 4156855 C T snv Chinese Crested (SRS713815)
7 4156887 4156888 G T snv Pembroke Welsh Corgi (SRS732551), Black Russian Terrier (SRS833812), Shetland Sheepdog (SRS932138), Border Terrier (SRS932144), Weimaraner (WE006), Weimaraner (WE008), West Highland White Terrier (WW174), West Highland White Terrier (WW64), Yorkshire Terrier (YT003), Australian Cattle dog (AC046), Australian Cattle dog (AC065), Australian Cattle dog (AC108), Bullmastiff (BU002), German Shepherd (GS3), Chinese Crested (SRS713815), Alpine Dachsbracke (AD009), Alaskan Malamute (AM007), Australian Shepherd (AU178), Border Collie (BC272), Border Collie (BC273), Beagle (BE020), Basset (BH003), Bullterrier (BT012), Chihuahua (CH019), Cocker Spaniel (CP003), Curly Coated Retriever (CR039), Dachshund (DH126), Chinese indigenous dogs (DQ10), Chinese indigenous dogs (DQ4), Entlebucher Sennenhund (EN154), Entlebucher Sennenhund (EN221), Entlebucher Sennenhund (EN247), Entlebucher Sennenhund (EN262), Entlebucher Sennenhund (EN263), Entlebucher Sennenhund (EN264), French Bulldog (FB046), French Bulldog (FB065), Golden Retriever (GR0855), Golden Retriever (GR0860), Golden Retriever (GR1078), German Spitz (GS104), German Shepherd (GS8), German Shepherd (GS9), German Wirehaired (GW004), Heideterrier (HT001), Hovawart (HW1706), Irish Terrier (IT221), Kunming Dog (KM10), Kunming Dog (KM3), Kunming Dog (KM4), Kunming Dog (KM8), Kunming Dog (KM9), Labrador Retriever (LA1869), Labrador Retriever (LA2382), Labrador Retriever (LA2443), Labrador Retriever (LA882), Labrador Retriever (LA900), Border Collie (LN47), Lagotto Romagnolo (LR433), Lagotto Romagnolo (LR654), Lagotto Romagnolo (LR753), Malinois (MA008), Malinois (MA0163), Malinois (MA094), Malinois (MA142), Malinois (MA324), Norwich Terrier (NW062), Norwich Terrier (NW152), Norwich Terrier (NW206), Spanish Water Dog (PE002), Rottweiler (RO2), Greater Swiss Mountain Dog (SH008)
7 4169157 4169158 G A snv Pomeranian (ZS14_2)
7 4169250 4169251 A T snv Australian Shepherd (AU178), Golden Retriever (GR0860), Malinois (MA324), Whippet (WH083), Border Collie (BC0480), Chinese indigenous dogs (DQ6), German Shepherd/Mixed breed (DS032), Golden Retriever (GR0859), Golden Retriever (GR0892), Greyhound (GY432), Kunming Dog (KM10), Chinese indigenous dogs (LJ9), Malinois (MA152), Rhodesian Ridgeback (RR098), Rhodesian Ridgeback (RR123), Rhodesian Ridgeback (RR224), Sloughi (SG005), Alaskan Husky (SY001)
7 4195095 4195096 A G snv German Wirehaired (GW004)
7 4218850 4218851 A T snv West Highland White Terrier (WW363), West Highland White Terrier (WW364), West Highland White Terrier (WW558), Chinese indigenous dogs (YJ1), Chinese indigenous dogs (YJ3), Chinese indigenous dogs (YJ4), Chinese indigenous dogs (YJ5), Landseer (ZS14), Tibetan Mastiff (TM3), West Highland White Terrier (WW174), West Highland White Terrier (WW362), Norwich Terrier (NW206), Alpine Dachsbracke (AD009), Bearded Collie (BD016), Bearded Collie (BD036), Bearded Collie (BD089), Bearded Collie (BD098), Basenji (BJ004), Basenji (BJ006), Miniature Bullterrier (BT007), Bullterrier (BT012), Cavalier King Charles Spaniel (CK006), Cavalier King Charles Spaniel (CK023), Dachshund (DH0117), Doberman Pinscher (DO242), Doberman Pinscher (DO263), Chinese indigenous dogs (DQ1), Chinese indigenous dogs (DQ6), Chinese indigenous dogs (DQ7), Chinese indigenous dogs (DQ8), Chinese indigenous dogs (DQ9), German Shepherd/Mixed breed (DS041), German Shepherd/Mixed breed (DS042), Golden Retriever (GR1078), German Shepherd (GS3), German Shepherd (GS4), German Shepherd (GS7), Heideterrier (HT001), Irish Terrier (IT0390), Irish Terrier (IT221), Jack Russell Terrier (JR0034), German Hunting Terrier (JT007), Jagdterrier (JT011), Kunming Dog (KM7), Kunming Dog (KM8), Labrador Retriever (LA1869), Labrador Retriever (LA2443), Leonberger (LB111), Leonberger (LB1919), Chinese indigenous dogs (LJ1), Chinese indigenous dogs (LJ2), Chinese indigenous dogs (LJ9), Malinois (MA0163), Malinois (MA142), Norwich Terrier (NW062), Norwich Terrier (NW152), Old English Sheepdog (OS001), Sloughi (SG005), Sloughi (SG006), Cavalier King Charles Spaniel (SID00101), Saluki (SL006), Iranian Wolf (SRS661488), Shetland Sheepdog (SS004), Tibetan Mastiff (TM10), Tibetan Mastiff (TM2), Tibetan Mastiff (TM5), Tibetan Mastiff (TM6), Tibetan Mastiff (TM7), Tibetan Mastiff (TM9), Whippet (WH083), Wolf (WO002_732), West Highland White Terrier (WW361)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011265 Ensembl
NCBI Gene PTPRC ENTREZGENE
UniProt F1Q1S4 ENTREZGENE
VGNC ID VGNC:45184 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 PTPRC  protein tyrosine phosphatase receptor type C    protein tyrosine phosphatase, receptor type C  Symbol and/or name change 5135510 APPROVED