Bp220 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp220 (Blood pressure QTL 220) Rattus norvegicus

Symbol: Bp220
Name: Blood pressure QTL 220
RGD ID: 1331750
Previously known as: Specialized Center of Research QTL 41,54,83; SCOR41; SCOR54; SCOR83
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: 2.98
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81339,968,211 - 84,968,211RGD_MAPPER_PIPELINE
mRatBN7.21337,415,584 - 82,415,584RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01342,310,744 - 87,310,744RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01347,416,073 - 92,416,073RGDRnor5.0
RGSC_v3.41338,489,801 - 83,489,801RGDRGSC3.4
RGSC_v3.11338,503,844 - 83,503,844RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Rathypertension  IAGP 70849 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Ratincreased systemic arterial diastolic blood pressure  IAGP 70849 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Ratdiastolic blood pressure  IDA 70849 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Ratcontrolled sodium content diet  IDA 70849 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Ratvascular indwelling catheter method  IDA 70849 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220RatBN/SsNHsd  IEA 70849 RGD 
Bp220RatSS/JrHsdMcwi  IEA 70849 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp220Ratarterial blood pressure trait  IDA 70849 RGD 


#
Reference Title
Reference Citation
1. Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study. Pan WH, etal., Hum Genet 2000 Sep;107(3):210-5.
2. A genomic-systems biology map for cardiovascular function. Stoll M, etal., Science 2001 Nov 23;294(5547):1723-6.

Related QTL Description Reference
Bp221 maps to same region RGD:70849
BP19_H maps to syntenic region RGD:1298024



1 to 20 of 595 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1564507Nckap5NCK-associated protein 5133736994838283257Rat
1592076Psme2-ps1proteasome activator subunit 2, pseudogene 1133818937538190347Rat
40941817Ftl1-ps11ferritin light chain 1, pseudogene 11133849046838492427Rat
1563709Tuba1c-ps1tubulin, alpha 1C, pseudogene 1133850749638508836Rat
41257974LOC120096238uncharacterized LOC120096238133857113338578302Rat
11417017LOC108352524cysteine and glycine-rich protein 2 pseudogene133858125138587400Rat
620100Mgat5alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase133867577638959697Rat
41024668LOC120096388small nucleolar RNA U6-53/MBII-28133885055138850659Rat
41170686LOC120096239uncharacterized LOC120096239133893059138934947Rat
1306212Tmem163transmembrane protein 163133896791339141664Rat
620868Acmsdaminocarboxymuconate semialdehyde decarboxylase133920041239245954Rat
1309205Ccnt2cyclin T2133925157339293172Rat
1566400Map3k19mitogen-activated protein kinase kinase kinase 19133930015039343502Rat
1306487Rab3gap1RAB3 GTPase activating protein catalytic subunit 1133935569839429154Rat
41267176LOC120096387small nucleolar RNA SNORA36 family133936360339363733Rat
1564952Zranb3zinc finger RANBP2-type containing 3133944065339595782Rat
7489024Mir3473microRNA 3473133949924639499312Rat
41023674Cmc1l1C-x(9)-C motif containing 1 like 1133951341939513580Rat
1307497R3hdm1R3H domain containing 1133959584839733876Rat
41108584LOC120096429U2 spliceosomal RNA133966495739665099Rat

1 to 20 of 595 rows
1 to 20 of 827 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
11084D13Mgh12125134215553442155659Ratregion
11115D13Mgh7418136202237462022792Ratregion
11232D13Arb7315134480209344802410Ratregion
33796D13Mit3216137474185474742070Ratregion
33935D13Mit8206134529565245295858Ratregion
33947D13Mit9160135305043453050594Ratregion
34351D13Mgh4142133741558437415726Ratregion
34534D13Mgh5140136105793861058078Ratregion
11375D13Arb8195134619287246193066Ratregion
11433D13Mgh15525134728269847283224Ratregion
33604D13Mit5244137474191674742160Ratregion
33733D13Mit2202135987440859874610Ratregion
35997D13Rat26169135478438754784556Ratregion
36033D13Rat29164136490158664901750Ratregion
36069D13Rat23166134570337045703527Ratregion
36197D13Rat42169137143707171437240Ratregion
37240D13Rat63103137704678777046890Ratregion
37314D13Rat101180134784107547841255Ratregion
37414D13Rat66195134245588642456081Ratregion
37554D13Rat57148138075325680753406Ratregion
1 to 20 of 827 rows

Flank 1: (D13Mgh4)
Rat AssemblyChrPosition (strand)Source
GRCr81339,968,211 - 39,968,353 (+)Marker Load Pipeline
mRatBN7.21337,415,584 - 37,415,726 (+)MAPPER
Rnor_6.01342,310,744 - 42,310,885NCBI
Rnor_5.01347,416,073 - 47,416,214UniSTS
RGSC_v3.41338,489,801 - 38,489,943RGD
RGSC_v3.41338,489,802 - 38,489,943UniSTS
RGSC_v3.11338,503,844 - 38,503,986RGD
Celera1337,210,510 - 37,210,651UniSTS
RH 2.0 Map13248.6RGD
SHRSP x BN Map137.9399RGD
FHH x ACI Map139.21RGD
Cytogenetic Map13q11UniSTS
Peak: (D13Mgh18)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map13193.8UniSTS
RH 3.4 Map13193.8RGD
Cytogenetic Map13q13UniSTS
Flank 2: (D13Mgh9)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map13522.9UniSTS
RH 3.4 Map13522.9RGD
RH 2.0 Map13587.8RGD
FHH x ACI Map1336.7799RGD
Cytogenetic Map13 RGD


1 to 10 of 64 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
12879436Bp395Blood pressure QTL 395arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134463918245700190Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
61453Pur1Proteinuria QTL 118.06urine total protein amount (VT:0000032)urine protein level (CMO:0000591)133453521837415726Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940445516593Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat

1 to 10 of 64 rows


Database
Acc Id
Source(s)
NCBI Gene Bp220

Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at A genomics-systems biology map for cardiovascular function 70849
qtl_general suggestive linkage found to the log dose of angiotensinII vs the blood pressure corresponding to that dose, for each of three doses (SCOR83,LOD2.5), and to diastolic blood pressure (SCOR41,LOD=2.55) 70849
qtl_general diastolic blood pressure standard deviation on low salt diet following Lasix, measured in basal state- lights on and rat asleep (SCOR54) 70849