Rasal2 (RAS protein activator like 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Rasal2 (RAS protein activator like 2) Rattus norvegicus
Analyze
Symbol: Rasal2
Name: RAS protein activator like 2
RGD ID: 1307566
Description: Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including adipose tissue development; response to dietary excess; and response to glucose. Orthologous to human RASAL2 (RAS protein activator like 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304893; ras GTPase-activating protein nGAP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21369,279,882 - 69,568,647 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1369,258,622 - 69,569,940 (-)Ensembl
Rnor_6.01374,770,557 - 75,059,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1374,771,522 - 75,059,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01379,688,195 - 79,976,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,381,047 - 72,534,202 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11372,395,925 - 72,686,393 (-)NCBI
Celera1369,114,622 - 69,264,415 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:25931508  


Genomics

Comparative Map Data
Rasal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21369,279,882 - 69,568,647 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1369,258,622 - 69,569,940 (-)Ensembl
Rnor_6.01374,770,557 - 75,059,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1374,771,522 - 75,059,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01379,688,195 - 79,976,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41372,381,047 - 72,534,202 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11372,395,925 - 72,686,393 (-)NCBI
Celera1369,114,622 - 69,264,415 (-)NCBICelera
Cytogenetic Map13q22NCBI
RASAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381178,094,104 - 178,478,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1178,094,104 - 178,484,147 (+)EnsemblGRCh38hg38GRCh38
GRCh371178,063,239 - 178,447,985 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,330,253 - 176,710,181 (+)NCBINCBI36hg18NCBI36
Build 341174,795,286 - 175,175,212NCBI
Celera1151,171,756 - 151,557,813 (+)NCBI
Cytogenetic Map1q25.2NCBI
HuRef1149,290,237 - 149,676,448 (+)NCBIHuRef
CHM1_11179,486,733 - 179,872,515 (+)NCBICHM1_1
T2T-CHM13v2.01177,448,790 - 177,833,573 (+)NCBI
Rasal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391156,962,753 - 157,240,170 (-)NCBIGRCm39mm39
GRCm39 Ensembl1156,962,752 - 157,240,165 (-)Ensembl
GRCm381157,135,183 - 157,412,595 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1157,135,182 - 157,412,595 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,065,314 - 159,342,726 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,070,842 - 159,342,069 (-)NCBImm8
Celera1159,539,962 - 159,820,171 (-)NCBICelera
Cytogenetic Map1H1NCBI
Rasal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540617,603,377 - 17,910,464 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540617,602,584 - 17,904,611 (+)NCBIChiLan1.0ChiLan1.0
RASAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11157,302,891 - 157,676,050 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1157,303,646 - 157,670,415 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01153,609,277 - 153,986,155 (+)NCBIMhudiblu_PPA_v0panPan3
RASAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1721,243,984 - 21,591,932 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl721,222,089 - 21,591,973 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha720,770,373 - 21,118,261 (-)NCBI
ROS_Cfam_1.0720,982,842 - 21,331,201 (-)NCBI
ROS_Cfam_1.0 Ensembl720,987,398 - 21,331,779 (-)Ensembl
UMICH_Zoey_3.1720,889,826 - 21,237,535 (-)NCBI
UNSW_CanFamBas_1.0720,997,571 - 21,345,351 (-)NCBI
UU_Cfam_GSD_1.0721,132,975 - 21,480,958 (-)NCBI
Rasal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934492,512,991 - 92,841,673 (-)NCBI
SpeTri2.0NW_00493648110,358,673 - 10,688,535 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9119,941,862 - 120,325,126 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19119,941,303 - 120,329,817 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29131,867,893 - 132,014,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RASAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12550,838,985 - 51,211,683 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2550,840,184 - 50,941,942 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605552,368,944 - 52,763,158 (-)NCBIVero_WHO_p1.0
Rasal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247713,797,187 - 4,126,379 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247713,791,337 - 4,125,982 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D13Got51  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21369,535,761 - 69,535,887 (+)MAPPERmRatBN7.2
Rnor_6.01375,026,588 - 75,026,713NCBIRnor6.0
Rnor_5.01379,943,650 - 79,943,775UniSTSRnor5.0
RGSC_v3.41372,638,816 - 72,638,941RGDRGSC3.4
RGSC_v3.41372,638,816 - 72,638,941UniSTSRGSC3.4
RGSC_v3.11372,653,004 - 72,653,129RGD
Celera1369,366,174 - 69,366,299UniSTS
RH 3.4 Map13403.5RGD
RH 3.4 Map13403.5UniSTS
RH 2.0 Map13502.1RGD
Cytogenetic Map13q22UniSTS
AU048429  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21369,402,608 - 69,402,711 (+)MAPPERmRatBN7.2
Rnor_6.01374,894,161 - 74,894,263NCBIRnor6.0
Rnor_5.01379,811,241 - 79,811,343UniSTSRnor5.0
RGSC_v3.41372,505,176 - 72,505,278UniSTSRGSC3.4
Celera1369,235,398 - 69,235,498UniSTS
Cytogenetic Map13q22UniSTS
AU048512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21369,357,282 - 69,357,452 (+)MAPPERmRatBN7.2
Rnor_6.01374,848,863 - 74,849,030NCBIRnor6.0
Rnor_5.01379,765,943 - 79,766,110UniSTSRnor5.0
RGSC_v3.41372,459,850 - 72,460,017UniSTSRGSC3.4
Celera1369,190,074 - 69,190,241UniSTS
Cytogenetic Map13q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)136906051977046890Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:68
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000033324
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 36 4 2 2 70 8 15 9 2
Low 3 7 52 40 19 40 6 9 4 27 26 2 6
Below cutoff 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000033324   ⟹   ENSRNOP00000033372
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,280,371 - 69,431,635 (-)Ensembl
Rnor_6.0 Ensembl1374,771,522 - 74,923,402 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089062   ⟹   ENSRNOP00000068634
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,280,371 - 69,337,674 (-)Ensembl
Rnor_6.0 Ensembl1374,772,015 - 75,059,326 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102068   ⟹   ENSRNOP00000089478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,283,166 - 69,569,940 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103896   ⟹   ENSRNOP00000092478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,258,622 - 69,569,940 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106934   ⟹   ENSRNOP00000083854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1369,258,622 - 69,569,940 (-)Ensembl
RefSeq Acc Id: NM_001107188   ⟹   NP_001100658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,976 - 69,431,635 (-)NCBI
Rnor_6.01374,771,522 - 74,923,402 (-)NCBI
Rnor_5.01379,688,195 - 79,976,930 (-)NCBI
RGSC_v3.41372,381,047 - 72,534,202 (-)RGD
Celera1369,114,622 - 69,264,415 (-)RGD
Sequence:
RefSeq Acc Id: XM_006250065   ⟹   XP_006250127
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,370,875 (-)NCBI
Rnor_6.01374,770,557 - 74,862,509 (-)NCBI
Rnor_5.01379,688,195 - 79,976,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250066   ⟹   XP_006250128
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,401,573 (-)NCBI
Rnor_6.01374,770,557 - 74,889,969 (-)NCBI
Rnor_5.01379,688,195 - 79,976,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250067   ⟹   XP_006250129
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,371,050 (-)NCBI
Rnor_6.01374,770,557 - 74,865,655 (-)NCBI
Rnor_5.01379,688,195 - 79,976,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769638   ⟹   XP_008767860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,568,647 (-)NCBI
Rnor_6.01374,770,557 - 75,059,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769639   ⟹   XP_008767861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,568,647 (-)NCBI
Rnor_6.01374,770,557 - 75,059,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598812   ⟹   XP_017454301
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,568,647 (-)NCBI
Rnor_6.01374,770,557 - 75,059,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598813   ⟹   XP_017454302
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,568,647 (-)NCBI
Rnor_6.01374,770,557 - 75,059,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090762   ⟹   XP_038946690
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,401,576 (-)NCBI
RefSeq Acc Id: XM_039090764   ⟹   XP_038946692
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,371,005 (-)NCBI
RefSeq Acc Id: XM_039090765   ⟹   XP_038946693
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,383,749 (-)NCBI
RefSeq Acc Id: XM_039090766   ⟹   XP_038946694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21369,279,882 - 69,401,577 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100658   ⟸   NM_001107188
- Sequence:
RefSeq Acc Id: XP_006250128   ⟸   XM_006250066
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006250129   ⟸   XM_006250067
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_006250127   ⟸   XM_006250065
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008767861   ⟸   XM_008769639
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JTA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767860   ⟸   XM_008769638
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017454302   ⟸   XM_017598813
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017454301   ⟸   XM_017598812
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000068634   ⟸   ENSRNOT00000089062
RefSeq Acc Id: ENSRNOP00000033372   ⟸   ENSRNOT00000033324
RefSeq Acc Id: XP_038946694   ⟸   XM_039090766
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038946690   ⟸   XM_039090762
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038946693   ⟸   XM_039090765
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038946692   ⟸   XM_039090764
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000092478   ⟸   ENSRNOT00000103896
RefSeq Acc Id: ENSRNOP00000083854   ⟸   ENSRNOT00000106934
RefSeq Acc Id: ENSRNOP00000089478   ⟸   ENSRNOT00000102068
Protein Domains
C2   PH   Ras-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTA7-F1-model_v2 AlphaFold A0A0G2JTA7 1-1279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 79712562 79712563 C T snv DOB/Oda (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307566 AgrOrtholog
BioCyc Gene G2FUF-17796 BioCyc
Ensembl Genes ENSRNOG00000004917 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000033372.4 UniProtKB/TrEMBL
  ENSRNOP00000068634.2 UniProtKB/TrEMBL
  ENSRNOP00000083854.1 UniProtKB/TrEMBL
  ENSRNOP00000089478 ENTREZGENE
  ENSRNOP00000089478.1 UniProtKB/TrEMBL
  ENSRNOP00000092478 ENTREZGENE
  ENSRNOP00000092478.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033324.6 UniProtKB/TrEMBL
  ENSRNOT00000089062.2 UniProtKB/TrEMBL
  ENSRNOT00000102068 ENTREZGENE
  ENSRNOT00000102068.1 UniProtKB/TrEMBL
  ENSRNOT00000103896 ENTREZGENE
  ENSRNOT00000103896.1 UniProtKB/TrEMBL
  ENSRNOT00000106934.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.506.10 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_Ca-dep UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DUF3498 UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
KEGG Report rno:304893 UniProtKB/TrEMBL
NCBI Gene 304893 ENTREZGENE
PANTHER PTHR10194 UniProtKB/TrEMBL
Pfam DUF3498 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
PhenoGen Rasal2 PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/TrEMBL
SMART RasGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP Rho_GAP UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
UniProt A0A0G2JTA7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWM6_RAT UniProtKB/TrEMBL
  A0A8I6ABU3_RAT UniProtKB/TrEMBL
  A0A8I6AI87_RAT UniProtKB/TrEMBL
  D4AAY3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rasal2  RAS protein activator like 2   Rasal2_predicted  RAS protein activator like 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rasal2_predicted  RAS protein activator like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED