Gene: Cacna1s (calcium voltage-gated channel subunit alpha1 S) Rattus norvegicus
Symbol: Cacna1s
Name: calcium voltage-gated channel subunit alpha1 S
Description: ENCODES a protein that exhibits high voltage-gated calcium channel activity; voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transport; cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH abnormal muscle development; ASSOCIATED WITH cutaneous malignant melanoma, susceptibility to, 1 (ortholog); hyperkalemic periodic paralysis (ortholog); Hypokalemic Periodic Paralysis (ortholog); FOUND IN sarcolemma; voltage-gated calcium channel complex; cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; furan
Type: protein-coding
Also known as: calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; calcium channel, voltage-dependent, L type, alpha 1S subunit; Cchl1a3; LOC501856; LOC682930; RGD1565743; ROB1; similar to dihydropyridine sensitive calcium channel; similar to Voltage-dependent L-type calcium channel alpha-1S subunit (Voltage-gated calcium channel alpha subunit Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle); voltage-dependent L-type calcium channel subunit alpha-1S; voltage-gated calcium channel subunit alpha Cav1.1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01352,889,570 - 52,964,558 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01357,945,479 - 58,018,760 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41349,096,012 - 49,103,925 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1347,809,765 - 47,877,622 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cacna1s
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70983
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE