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Gene: Pou2f1 (POU class 2 homeobox 1) Rattus norvegicus
Symbol: Pou2f1
Name: POU class 2 homeobox 1
RGD ID: 621689
Description: Exhibits chromatin binding activity; signaling receptor binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in liver regeneration and negative regulation of gene expression. Localizes to nucleus. Orthologous to human POU2F1 (POU class 2 homeobox 1); PARTICIPATES IN forkhead class A signaling pathway; RNA polymerase III transcription pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NF-A1; oct-1; octamer-binding protein 1; octamer-binding transcription factor 1; OTF-1; POU domain, class 2, transcription factor 1
Homo sapiens (human) : POU2F1 (POU class 2 homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Pou2f1 (POU domain, class 2, transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou2f1 (POU class 2 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU2F1 (POU class 2 homeobox 1)
Canis lupus familiaris (dog) : POU2F1 (POU class 2 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou2f1 (POU class 2 homeobox 1)
Sus scrofa (pig) : POU2F1 (POU class 2 homeobox 1)
Chlorocebus sabaeus (African green monkey) : POU2F1 (POU class 2 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pou2f1 (POU class 2 homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01384,075,316 - 84,217,368 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1384,083,632 - 84,217,366 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01388,957,996 - 89,095,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41381,607,326 - 81,739,958 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11381,639,808 - 81,649,784 (-)NCBI
Celera1377,841,488 - 77,973,453 (-)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pou2f1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621689
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.