C4bpb (complement component 4 binding protein, beta) - Rat Genome Database

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Gene: C4bpb (complement component 4 binding protein, beta) Rattus norvegicus
Analyze
Symbol: C4bpb
Name: complement component 4 binding protein, beta
RGD ID: 2236
Description: Predicted to be involved in several processes, including negative regulation of complement activation, classical pathway; regulation of opsonization; and response to symbiotic bacterium. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human C4BPB (complement component 4 binding protein beta); PARTICIPATES IN forkhead class A signaling pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C4b-binding protein beta chain; C4bp-ps1; MGC108727
RGD Orthologs
Human
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81344,673,064 - 44,683,781 (-)NCBIGRCr8
mRatBN7.21342,120,798 - 42,131,515 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,120,798 - 42,131,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1344,727,413 - 44,738,131 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,015,555 - 46,026,273 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,260,233 - 43,270,948 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,387,173 - 47,398,115 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,387,173 - 47,397,890 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,475,837 - 52,486,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,598,158 - 43,608,875 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11343,612,200 - 43,622,918 (-)NCBI
Celera1342,471,556 - 42,482,273 (-)NCBICelera
RH 3.4 Map13109.6RGD
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
Actein  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol AF  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dicrotophos  (ISO)
endosulfan  (EXP)
flavonoids  (EXP)
furan  (EXP)
glafenine  (EXP)
ketamine  (EXP)
lansoprazole  (EXP)
levonorgestrel  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
omeprazole  (EXP)
p-toluidine  (EXP)
pantoprazole  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
quercetin  (ISO)
rabeprazole  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
Tesaglitazar  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection. Ramlall V, etal., Nat Med. 2020 Aug 3. pii: 10.1038/s41591-020-1021-2. doi: 10.1038/s41591-020-1021-2.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. Webb JH, etal., J Immunol 2002 Sep 1;169(5):2580-6.
Additional References at PubMed
PMID:9013975   PMID:12477932   PMID:14607961   PMID:22333221  


Genomics

Comparative Map Data
C4bpb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81344,673,064 - 44,683,781 (-)NCBIGRCr8
mRatBN7.21342,120,798 - 42,131,515 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,120,798 - 42,131,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1344,727,413 - 44,738,131 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,015,555 - 46,026,273 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,260,233 - 43,270,948 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,387,173 - 47,398,115 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,387,173 - 47,397,890 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,475,837 - 52,486,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,598,158 - 43,608,875 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11343,612,200 - 43,622,918 (-)NCBI
Celera1342,471,556 - 42,482,273 (-)NCBICelera
RH 3.4 Map13109.6RGD
Cytogenetic Map13q13NCBI
C4BPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,088,860 - 207,099,993 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1207,088,860 - 207,099,993 (+)EnsemblGRCh38hg38GRCh38
GRCh371207,262,205 - 207,273,338 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,328,835 - 205,339,961 (+)NCBINCBI36Build 36hg18NCBI36
Build 341203,650,992 - 203,661,733NCBI
Celera1180,513,773 - 180,524,901 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1177,959,621 - 177,970,749 (+)NCBIHuRef
CHM1_11208,534,883 - 208,546,011 (+)NCBICHM1_1
T2T-CHM13v2.01206,354,100 - 206,365,236 (+)NCBIT2T-CHM13v2.0
C4bpb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540642,601,164 - 42,608,912 (+)NCBIChiLan1.0ChiLan1.0
C4BPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,274,861 - 42,286,955 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1142,240,852 - 42,252,295 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,691,574 - 182,703,004 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11186,969,905 - 186,981,024 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,970,253 - 186,981,024 (+)Ensemblpanpan1.1panPan2
C4BPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,224,962 - 6,236,925 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,225,188 - 6,236,918 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,788,185 - 5,800,200 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.075,913,641 - 5,925,664 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl75,913,912 - 5,925,657 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.175,847,314 - 5,859,304 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.075,948,804 - 5,960,803 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.075,988,967 - 6,001,074 (+)NCBIUU_Cfam_GSD_1.0
C4bpb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,306,397 - 68,319,286 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365575,546,692 - 5,561,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C4BPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,716,283 - 67,725,783 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1967,716,205 - 67,725,785 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2974,096,177 - 74,105,688 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C4BPB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,258,540 - 22,270,316 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,258,559 - 22,269,110 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605522,900,627 - 22,911,326 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C4bpb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,406,766 - 4,415,248 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248074,407,008 - 4,416,313 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C4bpb
65 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000005505
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134118402245417941Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat

Markers in Region
RH130286  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81344,673,090 - 44,673,831 (+)Marker Load Pipeline
mRatBN7.21342,120,824 - 42,121,565 (+)MAPPERmRatBN7.2
Rnor_6.01347,387,200 - 47,387,940NCBIRnor6.0
Rnor_5.01352,475,864 - 52,476,604UniSTSRnor5.0
RGSC_v3.41343,598,185 - 43,598,925UniSTSRGSC3.4
Celera1342,471,583 - 42,472,323UniSTS
Cytogenetic Map13q13UniSTS
RH130340  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,120,930 - 42,121,646 (+)MAPPERmRatBN7.2
Rnor_6.01347,387,306 - 47,388,021NCBIRnor6.0
Rnor_5.01352,475,970 - 52,476,685UniSTSRnor5.0
RGSC_v3.41343,598,291 - 43,599,006UniSTSRGSC3.4
Celera1342,471,689 - 42,472,404UniSTS
RH 3.4 Map13110.3UniSTS
Cytogenetic Map13q13UniSTS
RH142451  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map13109.6UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 47 108 90 90 59 25 59 6 215 94 89 45 59 31

Sequence


Ensembl Acc Id: ENSRNOT00000005505   ⟹   ENSRNOP00000005505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1342,120,799 - 42,131,527 (-)Ensembl
Rnor_6.0 Ensembl1347,387,173 - 47,397,890 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116656   ⟹   ENSRNOP00000095361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1342,120,798 - 42,131,817 (-)Ensembl
RefSeq Acc Id: NM_016995   ⟹   NP_058691
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81344,673,064 - 44,683,781 (-)NCBI
mRatBN7.21342,120,798 - 42,131,515 (-)NCBI
Rnor_6.01347,387,173 - 47,397,890 (-)NCBI
Rnor_5.01352,475,837 - 52,486,651 (-)NCBI
RGSC_v3.41343,598,158 - 43,608,875 (-)RGD
Celera1342,471,556 - 42,482,273 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058691 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88152 (Get FASTA)   NCBI Sequence Viewer  
  CAA90392 (Get FASTA)   NCBI Sequence Viewer  
  EDM09856 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005505.3
  ENSRNOP00000095361.1
  ENSRNOP00055029187
  ENSRNOP00060027060
GenBank Protein Q63515 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058691   ⟸   NM_016995
- Peptide Label: precursor
- UniProtKB: Q63515 (UniProtKB/Swiss-Prot),   A0A5C5 (UniProtKB/TrEMBL),   A6IBZ1 (UniProtKB/TrEMBL),   F7EP12 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005505   ⟸   ENSRNOT00000005505
Ensembl Acc Id: ENSRNOP00000095361   ⟸   ENSRNOT00000116656
Protein Domains
Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63515-F1-model_v2 AlphaFold Q63515 1-258 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698786
Promoter ID:EPDNEW_R9311
Type:multiple initiation site
Name:C4bpb_1
Description:complement component 4 binding protein, beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01347,397,895 - 47,397,955EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2236 AgrOrtholog
BioCyc Gene G2FUF-18370 BioCyc
Ensembl Genes ENSRNOG00000004125 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055021031 UniProtKB/Swiss-Prot
  ENSRNOG00060019117 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005505.5 UniProtKB/TrEMBL
  ENSRNOT00000116656.1 UniProtKB/TrEMBL
  ENSRNOT00055035930 UniProtKB/Swiss-Prot
  ENSRNOT00060033067 UniProtKB/Swiss-Prot
Gene3D-CATH Complement Module, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7322205 IMAGE-MGC_LOAD
InterPro SEZ6_CSMD_C4BPB_Regulators UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24236 UniProtKB/TrEMBL
MGC_CLONE MGC:108727 IMAGE-MGC_LOAD
NCBI Gene 24236 ENTREZGENE
PANTHER PROTEIN BETA CHAIN, PUTATIVE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN CBR-CLEC-78 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C4bpb PhenoGen
PROSITE SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004125 RatGTEx
  ENSRNOG00055021031 RatGTEx
  ENSRNOG00060019117 RatGTEx
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5C5 ENTREZGENE
  A0A8I6GLL0_RAT UniProtKB/TrEMBL
  A6IBZ1 ENTREZGENE, UniProtKB/TrEMBL
  C4BPB_RAT UniProtKB/Swiss-Prot
  F7EP12 ENTREZGENE, UniProtKB/TrEMBL
  Q63515 ENTREZGENE
UniProt Secondary A0A5C5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-02-15 C4bpb  complement component 4 binding protein, beta  C4bp-ps1  complement component 4 binding protein, pseudogene 1  Symbol and Name updated 1299863 APPROVED
2004-09-10 C4bp-ps1  complement component 4 binding protein, pseudogene 1  C4bpb  complement component 4 binding protein, beta  Symbol and Name updated 1299863 APPROVED
2002-06-10 C4bpb  Complement component 4 binding protein, beta      Symbol and Name status set to approved 70586 APPROVED