Gene: Crb1 (crumbs 1, cell polarity complex component) Rattus norvegicus
Symbol: Crb1
Name: crumbs 1, cell polarity complex component
Description: ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN eye photoreceptor cell development (ortholog); membrane organization (ortholog); plasma membrane organization (ortholog); ASSOCIATED WITH abnormal Muller cell morphology; abnormal retinal pigmentation; disorganized retinal outer nuclear layer; ASSOCIATED WITH Idiopathic Juxtafoveal Retinal Telangiectasia; cone-rod dystrophy (ortholog); cutaneous malignant melanoma, susceptibility to, 1 (ortholog); FOUND IN microvillus; photoreceptor inner segment; cell-cell adherens junction (ortholog); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); all-trans-retinoic acid (ortholog)
Type: protein-coding
Also known as: crumbs family member 1, photoreceptor morphogenesis associated; crumbs homolog 1; crumbs homolog 1 (Drosophila); LOC304825
Homo sapiens (human) : CRB1 (crumbs 1, cell polarity complex component)  HGNC  Alliance
Mus musculus (house mouse) : Crb1 (crumbs family member 1, photoreceptor morphogenesis associated)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crb1 (crumbs 1, cell polarity complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : CRB1 (crumbs 1, cell polarity complex component)
Canis lupus familiaris (dog) : CRB1 (crumbs 1, cell polarity complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crb1 (crumbs 1, cell polarity complex component)
more info ...
Allele / Splice: Crb1m1  
Genetic Models: BN-Crb1m1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01356,270,519 - 56,462,893 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01361,292,273 - 61,369,526 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01361,413,282 - 61,480,872 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41352,558,317 - 52,725,099 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11352,572,656 - 52,715,591 (-)NCBI
Celera1351,073,846 - 51,253,703 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Crb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309947
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE