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Gene: RGD1564614 (similar to complement factor H-related protein) Rattus norvegicus
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Symbol: RGD1564614
Name: similar to complement factor H-related protein
RGD ID: 1564614
Description: Predicted to have complement component C3b binding activity and heparin binding activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; and lupus nephritis. Orthologous to human CFH (complement factor H); CFHR3 (complement factor H related 3); and CFHR4 (complement factor H related 4); INTERACTS WITH (+)-schisandrin B; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: complement factor H-related protein; complement factor H-related protein-like; LOC498241; similar to complement component factor H
Orthologs:
Homo sapiens (human) : CFHR3 (complement factor H related 3)  HGNC  Alliance
Mus musculus (house mouse) : Cfhr2 (complement factor H-related 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CFHR3 (complement factor H related 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01356,889,669 - 56,958,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1356,889,669 - 56,958,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01361,895,974 - 61,976,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41353,162,400 - 53,231,360 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1351,682,465 - 51,749,642 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on RGD1564614
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564614
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.