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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
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 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
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 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Neoplasm Metastasis | ISO | RGD:1315215 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21986133 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway AnnotationsReferences - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | Pipeline to import KEGG annotations from KEGG into RGD |
| 4. | RGD automated data pipeline |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedComparative Map Data| Pik3c2b (Rattus norvegicus - Norway rat) |
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| PIK3C2B (Homo sapiens - human) |
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| Pik3c2b (Mus musculus - house mouse) |
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| Pik3c2b (Chinchilla lanigera - long-tailed chinchilla) |
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| PIK3C2B (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PIK3C2B (Canis lupus familiaris - dog) |
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| Pik3c2b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PIK3C2B (Sus scrofa - pig) |
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| PIK3C2B (Chlorocebus sabaeus - African green monkey) |
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| Pik3c2b (Heterocephalus glaber - naked mole-rat) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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RNA-SEQ Expression| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 30 | 2 | 2 | 11 | 2 | 2 | 2 | 62 | 6 | 20 | 11 | 2 |
| Low | 13 | 55 | 39 | 8 | 39 | 6 | 9 | 12 | 29 | 20 | 6 | ||
| Below cutoff | 1 |
Nucleotide Sequences| RefSeq Transcripts | NM_001105951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006249754 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249756 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017598693 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017598694 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017598695 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017598696 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07020979 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01075131 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075132 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01075133 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | ENSRNOT00000042125 ⟹ ENSRNOP00000051488 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000090170 ⟹ ENSRNOP00000071933 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001105951 ⟹ NP_001099421 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
TGCCGGCGGCCTGGGCCGCGGTCCTGGCAGGAGCCGGTGAGCCTCGCGCGCCGTGCAGTGCGCThide sequence |
| RefSeq Acc Id: | XM_006249754 ⟹ XP_006249816 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GAGGCCCGGGTTCCCGCCGCCCCGCCCTCTGGCTCCCGCGACCAGGCGATTCGGTGTTGCGGCThide sequence |
| RefSeq Acc Id: | XM_006249756 ⟹ XP_006249818 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
AATATAATATAATATGTAAAGAACAAAGTCTCTTCATGTCATCCCAGATGGCTAACACAGATGThide sequence |
| RefSeq Acc Id: | XM_017598693 ⟹ XP_017454182 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
AGAGGCCCGGGTTCCCGCCGCCCCGCCCTCTGGCTCCCGCGACCAGGCGATTCGGTGTTGCGGChide sequence |
| RefSeq Acc Id: | XM_017598694 ⟹ XP_017454183 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GTTTTTGAAGGACTCATGAAGGTTGTCCTCTGATCTCCACATGTATCTGTGGCGTTCGTGCCTThide sequence |
| RefSeq Acc Id: | XM_017598695 ⟹ XP_017454184 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GGGGGGGGGTTAAGATTGAGTTTATTCTTAAGTTATGTGTATGCTTGTGGGGTTAGGTGCACAThide sequence |
| RefSeq Acc Id: | XM_017598696 ⟹ XP_017454185 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CAGAGCAAGGGGTTCTAGCCTTGAAAGCGACGACAATCTGCTAGCGGGAAGTGAGACTGCTGGChide sequence |
Protein Sequences| Protein RefSeqs | NP_001099421 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006249816 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249818 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017454182 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017454183 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017454184 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017454185 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | EDM09779 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_001099421 ⟸ NM_001105951 |
| - UniProtKB: | D3ZVF3 (UniProtKB/TrEMBL) |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | XP_006249816 ⟸ XM_006249754 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | XP_006249818 ⟸ XM_006249756 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A0G2K1Q0 (UniProtKB/TrEMBL) |
| - Sequence: |
MRQWSPPPQLGAGARPAGRGDPLSSAPIPPPRLRRASSRNDPTYPRPSEPSLERARSKCQPGTPhide sequence |
| RefSeq Acc Id: | XP_017454184 ⟸ XM_017598695 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | XP_017454185 ⟸ XM_017598696 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | XP_017454182 ⟸ XM_017598693 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | XP_017454183 ⟸ XM_017598694 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPAhide sequence |
| RefSeq Acc Id: | ENSRNOP00000071933 ⟸ ENSRNOT00000090170 |
| RefSeq Acc Id: | ENSRNOP00000051488 ⟸ ENSRNOT00000042125 |
TranscriptomePromoters| RGD ID: | 13698819 | ||||||||
| Promoter ID: | EPDNEW_R9343 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Pik3c2b_1 | ||||||||
| Description: | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunittype 2 beta | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Sequence Variants (Rnor 6.0)
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Damaging Variants| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 13 | 54940588 | 54940589 | C | T | snv | Crl:SD (UDEL) |
| 13 | 54943575 | 54943576 | A | C | snv | F344/Stm (KyushuU) |
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 13 | 49871598 | 49871599 | C | T | snv | CDR |
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1306541 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000029938 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000051488 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000071933 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000042125 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000090170 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.10.1070.11 | UniProtKB/TrEMBL |
| 1.25.40.70 | UniProtKB/TrEMBL | |
| 2.60.40.150 | UniProtKB/TrEMBL | |
| 3.30.1520.10 | UniProtKB/TrEMBL | |
| InterPro | ARM-type_fold | UniProtKB/TrEMBL |
| C2_Ca-dep | UniProtKB/TrEMBL | |
| C2_domain_sf | UniProtKB/TrEMBL | |
| Kinase-like_dom | UniProtKB/TrEMBL | |
| Phox | UniProtKB/TrEMBL | |
| PI3/4_kinase_cat_dom | UniProtKB/TrEMBL | |
| PI3/4_kinase_cat_sf | UniProtKB/TrEMBL | |
| PI3/4_kinase_CS | UniProtKB/TrEMBL | |
| PI3K_accessory_sf | UniProtKB/TrEMBL | |
| PI3K_C2 | UniProtKB/TrEMBL | |
| PI3K_ras-bd | UniProtKB/TrEMBL | |
| PI_Kinase | UniProtKB/TrEMBL | |
| PInositide-3_kin_accessory_dom | UniProtKB/TrEMBL | |
| PX_dom_sf | UniProtKB/TrEMBL | |
| PX_PI3K_C2_beta | UniProtKB/TrEMBL | |
| Ubiquitin-rel_dom | UniProtKB/TrEMBL | |
| KEGG Report | rno:289021 | UniProtKB/TrEMBL |
| NCBI Gene | 289021 | ENTREZGENE |
| PANTHER | PTHR10048 | UniProtKB/TrEMBL |
| Pfam | PF00168 | UniProtKB/TrEMBL |
| PF00787 | UniProtKB/TrEMBL | |
| PI3_PI4_kinase | UniProtKB/TrEMBL | |
| PI3K_C2 | UniProtKB/TrEMBL | |
| PI3K_rbd | UniProtKB/TrEMBL | |
| PI3Ka | UniProtKB/TrEMBL | |
| PhenoGen | Pik3c2b | PhenoGen |
| PROSITE | PI3_4_KINASE_1 | UniProtKB/TrEMBL |
| PI3_4_KINASE_2 | UniProtKB/TrEMBL | |
| PI3_4_KINASE_3 | UniProtKB/TrEMBL | |
| PI3K_C2 | UniProtKB/TrEMBL | |
| PI3K_RBD | UniProtKB/TrEMBL | |
| PIK_HELICAL | UniProtKB/TrEMBL | |
| PS50004 | UniProtKB/TrEMBL | |
| PS50195 | UniProtKB/TrEMBL | |
| SMART | PI3K_C2 | UniProtKB/TrEMBL |
| PI3K_rbd | UniProtKB/TrEMBL | |
| PI3Ka | UniProtKB/TrEMBL | |
| PI3Kc | UniProtKB/TrEMBL | |
| SM00239 | UniProtKB/TrEMBL | |
| SM00312 | UniProtKB/TrEMBL | |
| Superfamily-SCOP | 64268 | UniProtKB/TrEMBL |
| ARM-type_fold | UniProtKB/TrEMBL | |
| Kinase_like | UniProtKB/TrEMBL | |
| SSF54236 | UniProtKB/TrEMBL | |
| UniGene | Rn.72591 | ENTREZGENE |
| UniProt | A0A0G2K1Q0 | ENTREZGENE, UniProtKB/TrEMBL |
| D3ZVF3 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2012-10-11 | Pik3c2b | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | Pik3c2b | nuclear cap binding protein subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2012-10-10 | Pik3c2b | nuclear cap binding protein subunit 2 | Pik3c2b | nuclear cap binding protein subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2012-10-10 | Pik3c2b | nuclear cap binding protein subunit 2 | Pik3c2b | phosphoinositide-3-kinase, class 2, beta polypeptide | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-04-30 | Pik3c2b | phosphoinositide-3-kinase, class 2, beta polypeptide | Pik3c2b_predicted | phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Pik3c2b_predicted | phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Pik3c2b | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1306541 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-06-09 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
