Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Neoplasm Metastasis | | ISO | PIK3C2B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21986133 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Neoplasm Metastasis | | ISO | PIK3C2B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21986133 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Pik3c2b (Rattus norvegicus - Norway rat) |
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PIK3C2B (Homo sapiens - human) |
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Pik3c2b (Mus musculus - house mouse) |
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Pik3c2b (Chinchilla lanigera - long-tailed chinchilla) |
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PIK3C2B (Pan paniscus - bonobo/pygmy chimpanzee) |
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PIK3C2B (Canis lupus familiaris - dog) |
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Pik3c2b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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PIK3C2B (Sus scrofa - pig) |
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PIK3C2B (Chlorocebus sabaeus - green monkey) |
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Pik3c2b (Heterocephalus glaber - naked mole-rat) |
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Variants in Pik3c2b
256 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 30 | 2 | 2 | 11 | 2 | 2 | 2 | 62 | 6 | 20 | 11 | 2 |
Low | 13 | 55 | 39 | 8 | 39 | 6 | 9 | 12 | 29 | 20 | 6 | ||
Below cutoff | 1 |
RefSeq Transcripts | NM_001105951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006249754 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006249756 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598693 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598694 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598695 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598696 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272073 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272074 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272075 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JAXUCZ010000013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000042125 ⟹ ENSRNOP00000051488 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000090170 ⟹ ENSRNOP00000071933 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001105951 ⟹ NP_001099421 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006249754 ⟹ XP_006249816 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006249756 ⟹ XP_006249818 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063272073 ⟹ XP_063128143 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272074 ⟹ XP_063128144 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272075 ⟹ XP_063128145 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001099421 | (Get FASTA) | NCBI Sequence Viewer |
XP_006249816 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006249818 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128143 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128144 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128145 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDM09779 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000051488 | ||
ENSRNOP00000051488.3 | |||
ENSRNOP00000071933 | |||
ENSRNOP00000071933.2 |
RefSeq Acc Id: | NP_001099421 ⟸ NM_001105951 |
- UniProtKB: | D3ZVF3 (UniProtKB/TrEMBL), A6IC68 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006249816 ⟸ XM_006249754 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2K1Q0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006249818 ⟸ XM_006249756 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A0A0G2K1Q0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000071933 ⟸ ENSRNOT00000090170 |
RefSeq Acc Id: | ENSRNOP00000051488 ⟸ ENSRNOT00000042125 |
RefSeq Acc Id: | XP_063128144 ⟸ XM_063272074 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128145 ⟸ XM_063272075 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_063128143 ⟸ XM_063272073 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZVF3-F1-model_v2 | AlphaFold | D3ZVF3 | 1-1621 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698819 | ||||||||
Promoter ID: | EPDNEW_R9343 | ||||||||
Type: | initiation region | ||||||||
Name: | Pik3c2b_1 | ||||||||
Description: | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunittype 2 beta | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1306541 | AgrOrtholog |
BioCyc Gene | G2FUF-18294 | BioCyc |
Ensembl Genes | ENSRNOG00000029938 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000042125 | ENTREZGENE |
ENSRNOT00000042125.5 | UniProtKB/TrEMBL | |
ENSRNOT00000090170.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.10.1070.11 | UniProtKB/TrEMBL |
1.25.40.70 | UniProtKB/TrEMBL | |
2.60.40.150 | UniProtKB/TrEMBL | |
3.30.1520.10 | UniProtKB/TrEMBL | |
InterPro | ARM-type_fold | UniProtKB/TrEMBL |
C2_Ca-dep | UniProtKB/TrEMBL | |
C2_domain_sf | UniProtKB/TrEMBL | |
Kinase-like_dom | UniProtKB/TrEMBL | |
Phox | UniProtKB/TrEMBL | |
PI3/4_kinase_cat_dom | UniProtKB/TrEMBL | |
PI3/4_kinase_cat_sf | UniProtKB/TrEMBL | |
PI3/4_kinase_CS | UniProtKB/TrEMBL | |
PI3K_accessory_sf | UniProtKB/TrEMBL | |
PI3K_C2 | UniProtKB/TrEMBL | |
PI3K_ras-bd | UniProtKB/TrEMBL | |
PI_Kinase | UniProtKB/TrEMBL | |
PInositide-3_kin_accessory_dom | UniProtKB/TrEMBL | |
PX_dom_sf | UniProtKB/TrEMBL | |
PX_PI3K_C2_beta | UniProtKB/TrEMBL | |
Ubiquitin-rel_dom | UniProtKB/TrEMBL | |
KEGG Report | rno:289021 | UniProtKB/TrEMBL |
NCBI Gene | 289021 | ENTREZGENE |
PANTHER | PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA | UniProtKB/TrEMBL |
PTHR10048 | UniProtKB/TrEMBL | |
Pfam | PF00168 | UniProtKB/TrEMBL |
PF00787 | UniProtKB/TrEMBL | |
PI3_PI4_kinase | UniProtKB/TrEMBL | |
PI3K_C2 | UniProtKB/TrEMBL | |
PI3K_rbd | UniProtKB/TrEMBL | |
PI3Ka | UniProtKB/TrEMBL | |
PhenoGen | Pik3c2b | PhenoGen |
PROSITE | PI3_4_KINASE_1 | UniProtKB/TrEMBL |
PI3_4_KINASE_2 | UniProtKB/TrEMBL | |
PI3_4_KINASE_3 | UniProtKB/TrEMBL | |
PI3K_C2 | UniProtKB/TrEMBL | |
PI3K_RBD | UniProtKB/TrEMBL | |
PIK_HELICAL | UniProtKB/TrEMBL | |
PS50004 | UniProtKB/TrEMBL | |
PS50195 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000029938 | RatGTEx |
SMART | PI3K_C2 | UniProtKB/TrEMBL |
PI3K_rbd | UniProtKB/TrEMBL | |
PI3Ka | UniProtKB/TrEMBL | |
PI3Kc | UniProtKB/TrEMBL | |
SM00239 | UniProtKB/TrEMBL | |
SM00312 | UniProtKB/TrEMBL | |
Superfamily-SCOP | 64268 | UniProtKB/TrEMBL |
ARM-type_fold | UniProtKB/TrEMBL | |
Kinase_like | UniProtKB/TrEMBL | |
SSF49562 | UniProtKB/TrEMBL | |
SSF54236 | UniProtKB/TrEMBL | |
UniProt | A0A0G2K1Q0 | ENTREZGENE, UniProtKB/TrEMBL |
A6IC68 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZVF3 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2012-10-11 | Pik3c2b | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | Pik3c2b | nuclear cap binding protein subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2012-10-10 | Pik3c2b | nuclear cap binding protein subunit 2 | Pik3c2b | nuclear cap binding protein subunit 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2012-10-10 | Pik3c2b | nuclear cap binding protein subunit 2 | Pik3c2b | phosphoinositide-3-kinase, class 2, beta polypeptide | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Pik3c2b | phosphoinositide-3-kinase, class 2, beta polypeptide | Pik3c2b_predicted | phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Pik3c2b_predicted | phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |