Mroh9 (maestro heat-like repeat family member 9) - Rat Genome Database

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Gene: Mroh9 (maestro heat-like repeat family member 9) Rattus norvegicus
Analyze
Symbol: Mroh9
Name: maestro heat-like repeat family member 9
RGD ID: 1564745
Description: Predicted to be active in cytoplasm. Orthologous to human MROH9 (maestro heat like repeat family member 9); INTERACTS WITH bromobenzene; benzo[a]pyrene (ortholog); beta-hexachlorocyclohexane (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: armadillo repeat containing 11; Armc11; LOC501864; maestro heat-like repeat-containing protein family member 9; RGD1564745; similar to hypothetical protein FLJ23550
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81377,921,039 - 77,976,343 (-)NCBIGRCr8
mRatBN7.21375,387,800 - 75,443,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1375,387,746 - 75,443,092 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01380,928,982 - 80,986,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1380,928,995 - 80,968,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01385,822,590 - 85,877,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,743,288 - 78,797,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1375,127,612 - 75,183,024 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Mroh9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81377,921,039 - 77,976,343 (-)NCBIGRCr8
mRatBN7.21375,387,800 - 75,443,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1375,387,746 - 75,443,092 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01380,928,982 - 80,986,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1380,928,995 - 80,968,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01385,822,590 - 85,877,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,743,288 - 78,797,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1375,127,612 - 75,183,024 (-)NCBICelera
Cytogenetic Map13q22NCBI
MROH9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381170,935,534 - 171,064,765 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1170,935,526 - 171,064,765 (+)EnsemblGRCh38hg38GRCh38
GRCh371170,904,675 - 171,033,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,171,260 - 169,234,571 (+)NCBINCBI36Build 36hg18NCBI36
Celera1144,014,146 - 144,143,886 (+)NCBICelera
Cytogenetic Map1q24.3NCBI
HuRef1142,128,251 - 142,257,272 (+)NCBIHuRef
CHM1_11172,326,896 - 172,456,184 (+)NCBICHM1_1
T2T-CHM13v2.01170,291,896 - 170,421,107 (+)NCBIT2T-CHM13v2.0
Mroh9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,851,871 - 162,913,239 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,851,871 - 162,913,239 (-)EnsemblGRCm39 Ensembl
GRCm381163,024,302 - 163,085,670 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1163,024,302 - 163,085,670 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,954,433 - 165,015,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,860,981 - 164,922,340 (-)NCBIMGSCv36mm8
Celera1165,457,039 - 165,519,725 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.34NCBI
Mroh9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,690,620 - 17,771,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,689,702 - 17,771,230 (-)NCBIChiLan1.0ChiLan1.0
MROH9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2178,693,215 - 78,825,562 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1178,366,712 - 78,499,060 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01146,425,586 - 146,557,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11150,141,104 - 150,273,143 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1150,141,104 - 150,273,143 (+)Ensemblpanpan1.1panPan2
MROH9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1727,799,722 - 27,898,885 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl727,800,009 - 27,898,869 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha727,326,847 - 27,431,690 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0727,601,153 - 27,700,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl727,601,779 - 27,700,709 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1727,451,274 - 27,550,683 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0727,486,209 - 27,585,697 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0727,728,300 - 27,827,629 (-)NCBIUU_Cfam_GSD_1.0
Mroh9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934498,160,316 - 98,213,580 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648116,007,209 - 16,051,687 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648116,007,155 - 16,057,502 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MROH9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl963,620,228 - 63,727,022 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1963,620,228 - 63,727,120 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MROH9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12558,019,372 - 58,150,474 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2558,087,764 - 58,129,094 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605559,664,644 - 59,785,043 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mroh9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747943,130 - 1,025,061 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747943,386 - 1,024,497 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:21
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000004931
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134760142692601426Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
AFM310VE1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21375,428,687 - 75,430,218 (+)MAPPERmRatBN7.2
Rnor_6.01380,971,845 - 80,973,375NCBIRnor6.0
Rnor_5.01385,864,562 - 85,866,092UniSTSRnor5.0
RGSC_v3.41378,785,314 - 78,786,844UniSTSRGSC3.4
Celera1375,168,495 - 75,170,025UniSTS
Cytogenetic Map13q22UniSTS


Expression

RNA-SEQ Expression

appendage
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 24 18 27 13 1 13 55 5 23 35 39 14

Sequence


Ensembl Acc Id: ENSRNOT00000004931   ⟹   ENSRNOP00000004931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1375,387,746 - 75,443,092 (-)Ensembl
Rnor_6.0 Ensembl1380,928,995 - 80,968,971 (-)Ensembl
RefSeq Acc Id: XM_008769706   ⟹   XP_008767928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81377,921,039 - 77,976,343 (-)NCBI
mRatBN7.21375,387,800 - 75,443,117 (-)NCBI
Rnor_6.01380,928,982 - 80,986,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769707   ⟹   XP_008767929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81377,921,039 - 77,976,343 (-)NCBI
mRatBN7.21375,387,800 - 75,443,118 (-)NCBI
Rnor_6.01380,928,982 - 80,986,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769708   ⟹   XP_008767930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81377,921,039 - 77,976,343 (-)NCBI
mRatBN7.21375,387,800 - 75,443,117 (-)NCBI
Rnor_6.01380,928,982 - 80,986,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769709   ⟹   XP_008767931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81377,931,621 - 77,976,343 (-)NCBI
mRatBN7.21375,398,384 - 75,443,117 (-)NCBI
Rnor_6.01380,940,777 - 80,986,373 (-)NCBI
Sequence:
RefSeq Acc Id: XP_008767929   ⟸   XM_008769707
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767930   ⟸   XM_008769708
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008767928   ⟸   XM_008769706
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008767931   ⟸   XM_008769709
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000004931   ⟸   ENSRNOT00000004931

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M2I1-F1-model_v2 AlphaFold F1M2I1 1-771 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564745 AgrOrtholog
BioCyc Gene G2FUF-17632 BioCyc
Ensembl Genes ENSRNOG00000003698 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004931.7 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Maestro_heat-like_prot UniProtKB/TrEMBL
  Maestro_HEAT_rpt UniProtKB/TrEMBL
KEGG Report rno:501864 UniProtKB/TrEMBL
NCBI Gene 501864 ENTREZGENE
PANTHER MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 9 UniProtKB/TrEMBL
  PTHR23120 UniProtKB/TrEMBL
Pfam Maestro_HEAT UniProtKB/TrEMBL
PhenoGen Mroh9 PhenoGen
RatGTEx ENSRNOG00000003698 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A6IDB6 ENTREZGENE, UniProtKB/TrEMBL
  F1M2I1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-02 Mroh9  maestro heat-like repeat family member 9  Armc11  armadillo repeat containing 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-11-21 Armc11  armadillo repeat containing 11  RGD1564745  similar to hypothetical protein FLJ23550  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564745  similar to hypothetical protein FLJ23550   RGD1564745_predicted  similar to hypothetical protein FLJ23550 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564745_predicted  similar to hypothetical protein FLJ23550 (predicted)  LOC501864  similar to hypothetical protein FLJ23550  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501864  similar to hypothetical protein FLJ23550      Symbol and Name status set to provisional 70820 PROVISIONAL