Lnnr6 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Lnnr6 (Liver neoplastic nodule remodeling QTL 6) Rattus norvegicus

Symbol: Lnnr6
Name: Liver neoplastic nodule remodeling QTL 6
RGD ID: 738027
Previously known as: Hcrem6
Trait: liver integrity trait   (VT:0010547)    
Measurement Type: liver remodeling tumorous lesion number   (CMO:0001461)    
LOD Score: 3.3
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81365,613,454 - 109,350,286RGD_MAPPER_PIPELINE
mRatBN7.21374,862,117 - 85,581,182RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01380,403,559 - 91,629,354RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01385,295,639 - 96,143,898RGDRnor5.0
RGSC_v3.41378,189,125 - 111,154,910RGDRGSC3.4
RGSC_v3.11378,203,445 - 111,348,958RGD
Cross Type: intercross
Strains Crossed: COP F344/NRrrc 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6RatExperimental Liver Neoplasms  IDA 737884 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6Ratdecreased liver tumor incidence  IDA 737884 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6Ratliver remodeling tumorous lesion number  IDA 737884 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6Rat2-acetamidofluorene  IDA 737884 RGD 
Lnnr6Ratcontrolled protein content diet  IDA 737884 RGD 
Lnnr6RatN-nitrosodiethylamine  IDA 737884 RGD 
Lnnr6Ratpartial hepatectomy  IDA 737884 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6Ratex vivo light microscopy with digital image analysis  IDA 737884 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6RatCOP  IEA 737884 RGD 
Lnnr6RatF344/NRrrc  IEA 737884 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lnnr6Ratliver integrity trait  IDA 737884 RGD 


#
Reference Title
Reference Citation
1. Polygenic control of hepatocarcinogenesis in Copenhagen xF344 rats De Miglio MR, etal., Int J Cancer 2004 Aug 10;111(1):9-16.


1 to 20 of 272 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1311526Mettl13methyltransferase 13, eEF1A N-terminus and K55137488615174899937Rat
41165488LOC120096299uncharacterized LOC120096299137491488974916011Rat
1309753Vamp4vesicle-associated membrane protein 4137491987274942791Rat
620430Myocmyocilin137497673074987128Rat
1566064Prrc2cproline-rich coiled-coil 2C137500399575073701Rat
7598395LOC102555487uncharacterized LOC102555487137514960175157370Rat
628601Fmo4flavin containing dimethylaniline monoxygenase 4137515468375172874Rat
2622Fmo1flavin containing dimethylaniline monoxygenase 1137518218475214439Rat
628600Fmo2flavin containing dimethylaniline monoxygenase 2137522114975244377Rat
1594389Hsp90aa1-ps13heat shock protein 90 alpha family class A member 1, pseudogene 13137525157375254102Rat
1559491Fmo6flavin containing monooxygenase 6137525661775288167Rat
619761Fmo3flavin containing dimethylaniline monoxygenase 3137530936775334915Rat
1564745Mroh9maestro heat-like repeat family member 9137538780075443118Rat
40929598LOC120096402small nucleolar RNA SNORA17137540782675407928Rat
9112028LOC10369202040S ribosomal protein S8 pseudogene137559070675593669Rat
628884Prrx1paired related homeobox 1137560077775671896Rat
41312610LOC120096300uncharacterized LOC120096300137566651575684794Rat
1584663Cct6a-ps8chaperonin containing Tcp1, subunit 6A (zeta 1), pseudogene 8137569179975693451Rat
1564990Gorabgolgin, RAB6-interacting137574567875762307Rat
1564106Ntmt2N-terminal Xaa-Pro-Lys N-methyltransferase 2137605068376093972Rat

1 to 20 of 272 rows
1 to 20 of 279 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10204D13Arb11234138475327784753511Ratregion
10205D13Mgh17398138475311384753510Ratregion
34540D13Mgh14238138475531884755556Ratregion
37240D13Rat63103137704678777046890Ratregion
37554D13Rat57148138075325680753406Ratregion
36506D13Rat32108137486211774862225Ratregion
34769D13Rat33161137847270778472868Ratregion
39950D13Rat133115138300588983006034Ratregion
40568D13Rat152109138558107385581182Ratregion
40656D13Rat131155137731293377313088Ratregion
38582D13Rat56235138169065581690878Ratregion
41970D13Arb13132138473106684731198Ratregion
43001D13Rat183202137752353677523740Ratregion
43002D13Rat184227137927434979274584Ratregion
43004D13Rat185192138383241983832611Ratregion
41112D13Rat132228137829113278291378Ratregion
41900D13Rat190135138015760680157741Ratregion
45062D13Got55173137647835976478532Ratregion
45067D13Got111192137558793975588131Ratregion
45070D13Got61235137769764277697877Ratregion
1 to 20 of 279 rows

Flank 1: (D13Rat32)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21374,862,117 - 74,862,225 (+)MAPPER
Rnor_6.01380,403,559 - 80,403,666NCBI
Rnor_5.01385,295,639 - 85,295,746UniSTS
RGSC_v3.41378,189,125 - 78,189,379RGD
RGSC_v3.41378,189,257 - 78,189,364UniSTS
RGSC_v3.11378,203,445 - 78,203,552RGD
Celera1374,612,920 - 74,613,027UniSTS
RH 3.4 Map13468.2UniSTS
RH 3.4 Map13468.2RGD
RH 2.0 Map13507.8RGD
SHRSP x BN Map1330.5998RGD
FHH x ACI Map1330.36RGD
Peak: (D13Rat152)
Rat AssemblyChrPosition (strand)Source
GRCr81388,113,400 - 88,113,509 (+)Marker Load Pipeline
mRatBN7.21385,581,073 - 85,581,182 (+)MAPPER
Rnor_6.01391,629,246 - 91,629,354NCBI
Rnor_5.01396,143,790 - 96,143,898UniSTS
Celera1385,185,751 - 85,185,859UniSTS
SHRSP x BN Map1340.7799RGD
SHRSP x BN Map1340.7799UniSTS
FHH x ACI Map1341.62RGD
Flank 2: (D13Rat152)
Rat AssemblyChrPosition (strand)Source
GRCr81388,113,400 - 88,113,509 (+)Marker Load Pipeline
mRatBN7.21385,581,073 - 85,581,182 (+)MAPPER
Rnor_6.01391,629,246 - 91,629,354NCBI
Rnor_5.01396,143,790 - 96,143,898UniSTS
Celera1385,185,751 - 85,185,859UniSTS
SHRSP x BN Map1340.7799RGD
SHRSP x BN Map1340.7799UniSTS
FHH x ACI Map1341.62RGD


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)136906051977046890Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat

1 to 10 of 38 rows


Database
Acc Id
Source(s)
NCBI Gene Lnnr6

Note Type Note Reference
qtl_cross_type intercross