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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Uhmk1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Uhmk1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UHMK1 mRNA | CTD | PMID:36331819 | Uhmk1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of UHMK1 mRNA | CTD | PMID:22206623 | Uhmk1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of UHMK1 mRNA | CTD | PMID:12072388 | Uhmk1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of UHMK1 mRNA | CTD | PMID:29097150 | Uhmk1 | Rat | 17beta-estradiol | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of UHMK1 mRNA | CTD | PMID:21632981 | Uhmk1 | Rat | 17beta-estradiol | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in decreased expression of UHMK1 mRNA | CTD | PMID:22217510 | Uhmk1 | Rat | 17beta-estradiol | decreases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of UHMK1 mRNA | CTD | PMID:19484750 | Uhmk1 | Rat | 17beta-estradiol | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of UHMK1 mRNA | CTD | PMID:23019147 | Uhmk1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Uhmk1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Uhmk1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Uhmk1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Uhmk1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of UHMK1 mRNA | CTD | PMID:22298810 | Uhmk1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of UHMK1 mRNA | CTD | PMID:21570461 and PMID:24680724 | Uhmk1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UHMK1 mRNA | CTD | PMID:21215274 and PMID:33387578 | Uhmk1 | Rat | 5-azacytidine | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of UHMK1 mRNA | CTD | PMID:20823114 | Uhmk1 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of UHMK1 mRNA | CTD | PMID:31881176 | Uhmk1 | Rat | acrolein | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of UHMK1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of UHMK1 mRNA | CTD | PMID:32699268 | Uhmk1 | Rat | aflatoxin M1 | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of UHMK1 mRNA | CTD | PMID:30928695 | Uhmk1 | Rat | alpha-pinene | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of UHMK1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of UHMK1 mRNA | CTD | PMID:32699268 | Uhmk1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of UHMK1 mRNA | CTD | PMID:16483693 | Uhmk1 | Rat | arsenite(3-) | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to UHMK1 mRNA] | CTD | PMID:32406909 | Uhmk1 | Rat | arsenous acid | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KIS mRNA | CTD | PMID:20458559 | Uhmk1 | Rat | benzo[a]pyrene | increases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of UHMK1 mRNA | CTD | PMID:20127859 | Uhmk1 | Rat | benzo[a]pyrene | affects methylation | ISO | UHMK1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of UHMK1 promoter | CTD | PMID:27901495 | Uhmk1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | Uhmk1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UHMK1 mRNA | CTD | PMID:26982218 more ... | Uhmk1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of UHMK1 mRNA | CTD | PMID:25181051 | Uhmk1 | Rat | cadmium atom | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UHMK1 mRNA | CTD | PMID:35301059 | Uhmk1 | Rat | cadmium dichloride | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UHMK1 mRNA | CTD | PMID:35301059 | Uhmk1 | Rat | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of UHMK1 mRNA | CTD | PMID:18500788 | Uhmk1 | Rat | chlorpyrifos | decreases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of UHMK1 mRNA | CTD | PMID:37019170 | Uhmk1 | Rat | coumestrol | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of UHMK1 mRNA | CTD | PMID:19167446 | Uhmk1 | Rat | CU-O LINKAGE | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of UHMK1 mRNA | CTD | PMID:22077320 | Uhmk1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of UHMK1 mRNA | CTD | PMID:27523638 | Uhmk1 | Rat | cyclosporin A | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of UHMK1 mRNA | CTD | PMID:25562108 | Uhmk1 | Rat | diarsenic trioxide | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KIS mRNA | CTD | PMID:20458559 | Uhmk1 | Rat | dorsomorphin | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | ethanol | affects splicing | ISO | Uhmk1 (Mus musculus) | 6480464 | Ethanol affects the splicing of UHMK1 mRNA | CTD | PMID:30319688 | Uhmk1 | Rat | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of UHMK1 mRNA | CTD | PMID:18035473 | Uhmk1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of UHMK1 mRNA | CTD | PMID:25539665 | Uhmk1 | Rat | geldanamycin | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of UHMK1 mRNA | CTD | PMID:26705709 | Uhmk1 | Rat | iron dichloride | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | ferrous chloride results in increased expression of UHMK1 mRNA | CTD | PMID:35984750 | Uhmk1 | Rat | kainic acid | decreases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | Kainic Acid results in decreased expression of UHMK1 mRNA | CTD | PMID:17997037 | Uhmk1 | Rat | lead diacetate | decreases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | lead acetate results in decreased expression of UHMK1 mRNA | CTD | PMID:21829687 | Uhmk1 | Rat | leflunomide | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of UHMK1 mRNA | CTD | PMID:28988120 | Uhmk1 | Rat | mercury dichloride | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of UHMK1 mRNA | CTD | PMID:22584684 | Uhmk1 | Rat | methylmercury chloride | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of UHMK1 mRNA | CTD | PMID:28001369 | Uhmk1 | Rat | nickel atom | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Nickel results in increased expression of UHMK1 mRNA | CTD | PMID:24768652 | Uhmk1 | Rat | ozone | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of UHMK1 mRNA more ... | CTD | PMID:32699268 | Uhmk1 | Rat | paracetamol | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of UHMK1 mRNA | CTD | PMID:22230336 | Uhmk1 | Rat | PCB138 | multiple interactions | ISO | Uhmk1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Uhmk1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Uhmk1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UHMK1 mRNA | CTD | PMID:36331819 | Uhmk1 | Rat | pirinixic acid | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of UHMK1 mRNA | CTD | PMID:19710929 | Uhmk1 | Rat | quercetin | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of UHMK1 mRNA | CTD | PMID:21632981 | Uhmk1 | Rat | resveratrol | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of UHMK1 mRNA | CTD | PMID:23557933 | Uhmk1 | Rat | SB 431542 | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | sodium arsenite | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of UHMK1 mRNA | CTD | PMID:38568856 | Uhmk1 | Rat | thimerosal | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of UHMK1 mRNA | CTD | PMID:34492290 | Uhmk1 | Rat | trichostatin A | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of UHMK1 mRNA | CTD | PMID:26272509 | Uhmk1 | Rat | trichostatin A | multiple interactions | ISO | UHMK1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | triphenyl phosphate | affects expression | ISO | UHMK1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of UHMK1 mRNA | CTD | PMID:37042841 | Uhmk1 | Rat | triptonide | increases expression | ISO | Uhmk1 (Mus musculus) | 6480464 | triptonide results in increased expression of UHMK1 mRNA | CTD | PMID:33045310 | Uhmk1 | Rat | urethane | increases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Urethane results in increased expression of UHMK1 mRNA | CTD | PMID:28818685 | Uhmk1 | Rat | valproic acid | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | Uhmk1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of UHMK1 mRNA | CTD | PMID:23034163 | Uhmk1 | Rat | vorinostat | decreases expression | ISO | UHMK1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of UHMK1 mRNA | CTD | PMID:27188386 | |