Bp396 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp396 (Blood pressure QTL 396) Rattus norvegicus

Symbol: Bp396
Name: Blood pressure QTL 396
RGD ID: 12879441
Previously known as: Linne9BP2
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,699,983 - 90,699,983RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01351,080,989 - 96,080,989RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01356,136,324 - 101,136,324RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41347,198,168 - 48,990,782RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.BN-(2340-RN34_13048990782)/Mcwi 



Ptprv is a candidate Gene for Bp396
Rnpep is a candidate Gene for Bp396


Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp396Ratmean arterial blood pressure  IDA 12802369 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp396Ratcontrolled sodium content diet  IDA 12802369 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp396Ratintra-aortic abdominal radiotelemetry via femoral cannulation  IDA 12802369 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp396RatSS.BN-(2340-RN34_13048990782)/Mcwi  IEA 12802369 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp396Ratarterial blood pressure trait  IDA 12802369 RGD 


#
Reference Title
Reference Citation
1. Congenic mapping and sequence analysis of the Renin locus. Flister MJ, etal., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.


1 to 20 of 708 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
620432Myogmyogenin134574545545748044Rat
620055Ppfia4PTPRF interacting protein alpha 4134575382745802305Rat
41016284LOC120096189uncharacterized LOC120096189134575604045759682Rat
1309892Tmem183atransmembrane protein 183A134580364145820409Rat
1359351Mgat4fMGAT4 family, member F134583745845843215Rat
41359476LOC120096190uncharacterized LOC120096190134584375445854407Rat
1306084Cyb5r1cytochrome b5 reductase 1134584901745855458Rat
1303151Adipor1adiponectin receptor 1134585946145879248Rat
9078385Lnc134long non-coding RNA 134134589496445899883Rat
628717Klhl12kelch-like family member 12134589991345933648Rat
1583292Ndufv3-ps1NADH:ubiquinone oxidoreductase subunit V3, pseudogene 1134591624045916673Rat
1359331RabifRAB interacting factor134593637145948929Rat
1592636Rps7-ps10ribosomal protein S7, pseudogene 10134595072345951394Rat
1308112Mgat4eMGAT4 family member E134598297945991793Rat
1565602Kdm5blysine demethylase 5B134600158946073868Rat
3804Syt2synaptotagmin 2134608804646197976Rat
1309287Ppp1r12bprotein phosphatase 1, regulatory subunit 12B134619941846397108Rat
41052885Ube2c-ps4ubiquitin-conjugating enzyme E2C, pseudogene 4134623456746243280Rat
1310816Ube2tubiquitin-conjugating enzyme E2T134640335246413854Rat
1560339Lgr6leucine-rich repeat-containing G protein-coupled receptor 6134642438246544074Rat

1 to 20 of 708 rows
1 to 20 of 828 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10204D13Arb11234138475327784753511Ratregion
10205D13Mgh17398138475311384753510Ratregion
10569D13Wox17223138568589585686118Ratregion
11115D13Mgh7418136202237462022792Ratregion
33796D13Mit3216137474185474742070Ratregion
33947D13Mit9160135305043453050594Ratregion
34534D13Mgh5140136105793861058078Ratregion
34540D13Mgh14238138475531884755556Ratregion
11375D13Arb8195134619287246193066Ratregion
11433D13Mgh15525134728269847283224Ratregion
33604D13Mit5244137474191674742160Ratregion
33644D13Mit4122138680077686800898Ratregion
33733D13Mit2202135987440859874610Ratregion
35997D13Rat26169135478438754784556Ratregion
36033D13Rat29164136490158664901750Ratregion
36069D13Rat23166134570337045703527Ratregion
36197D13Rat42169137143707171437240Ratregion
37240D13Rat63103137704678777046890Ratregion
37314D13Rat101180134784107547841255Ratregion
37554D13Rat57148138075325680753406Ratregion
1 to 20 of 828 rows

Flank 1: (D13Hmgc30)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21345,699,983 - 45,700,190 (+)MAPPER
Rnor_6.01351,080,989 - 51,081,193NCBI
Rnor_5.01356,136,324 - 56,136,528UniSTS
RGSC_v3.41347,198,168 - 47,198,372UniSTS
Celera1346,028,185 - 46,028,389UniSTS
Cytogenetic Map13 RGD
Flank 2: (RN34_13048990782)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.41348,990,782 - 48,990,782RGD


1 to 10 of 56 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
12879436Bp395Blood pressure QTL 395arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134463918245700190Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138473078886800898Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat

1 to 10 of 56 rows


Note Type Note Reference
qtl_general software used: statistics - Sigma Plot 11.0 12802369
qtl_trait Brown Norway alleles are hypertensive and increase albuminuria (only male rats used) 12802369
qtl_trait_method measurement method: mean arterial pressure was measured in congenic strain male rats after 21 days of 8% NaCl diet. Albumin excretion was measured after 17 days of 8% NaCl diet 12802369