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Gene: Akt3 (AKT serine/threonine kinase 3) Rattus norvegicus
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Symbol: Akt3
Name: AKT serine/threonine kinase 3
Description: Exhibits ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in cellular response to insulin stimulus; positive regulation of sodium ion transport; and protein phosphorylation. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma multiforme; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Orthologous to human AKT3 (AKT serine/threonine kinase 3); PARTICIPATES IN altered phosphatidylinositol 3-kinase-Akt signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 2-ethoxyethanol; 2-methoxyethanol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AKT3 kinase; PKB gamma; Pkbg; protein kinase Akt-3; protein kinase B gamma; protein kinase B, gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B gamma); v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Orthologs:
Homo sapiens (human) : AKT3 (AKT serine/threonine kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Akt3 (thymoma viral proto-oncogene 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akt3 (AKT serine/threonine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AKT3 (AKT serine/threonine kinase 3)
Canis lupus familiaris (dog) : AKT3 (AKT serine/threonine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akt3 (AKT serine/threonine kinase 3)
Sus scrofa (pig) : AKT3 (AKT serine/threonine kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01395,076,308 - 95,348,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01399,527,953 - 99,800,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41392,802,390 - 93,110,704 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11393,002,743 - 93,299,588 (-)NCBI
Celera1388,523,410 - 88,791,412 (-)NCBICelera
Cytogenetic Map13q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Akt3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62390
Created: 2001-04-26
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.