Akt3 (AKT serine/threonine kinase 3) - Rat Genome Database

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Gene: Akt3 (AKT serine/threonine kinase 3) Ictidomys tridecemlineatus
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Symbol: Akt3
Name: AKT serine/threonine kinase 3
RGD ID: 12463223
Description: ENCODES a protein that exhibits ATP binding (ortholog); protein kinase C binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN brain morphogenesis (ortholog); homeostasis of number of cells within a tissue (ortholog); mitochondrial genome maintenance (ortholog); PARTICIPATES IN altered phosphatidylinositol 3-kinase-Akt signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 16 (ortholog); colon cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: AKT serine/threonine kinase 3, transcript variant X1; AKT serine/threonine kinase 3, transcript variant X2; AKT serine/threonine kinase 3, transcript variant X3; AKT serine/threonine kinase 3, transcript variant X4; AKT serine/threonine kinase 3, transcript variant X5; AKT serine/threonine kinase 3, transcript variant X6; AKT serine/threonine kinase 3, transcript variant X7; AKT serine/threonine kinase 3, transcript variant X8; AKT serine/threonine kinase 3, transcript variant X9; RAC-gamma serine/threonine-protein kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934447,546,714 - 47,803,867 (-)NCBI
SpeTri2.0NW_0049365266,944,056 - 7,201,226 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Akt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934447,546,714 - 47,803,867 (-)NCBI
SpeTri2.0NW_0049365266,944,056 - 7,201,226 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1243,488,233 - 243,851,079 (-)EnsemblGRCh38hg38GRCh38
GRCh381243,488,233 - 243,851,079 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371243,651,535 - 244,014,381 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361241,718,158 - 242,073,176 (-)NCBINCBI36hg18NCBI36
Build 341239,977,575 - 240,332,594NCBI
Celera1216,939,341 - 217,293,898 (-)NCBI
Cytogenetic Map1q43-q44NCBI
HuRef1214,031,579 - 214,386,139 (-)NCBIHuRef
CHM1_11244,924,165 - 245,279,192 (-)NCBICHM1_1
Akt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,847,642 - 177,091,688 (-)NCBIGRCm39mm39
GRCm39 Ensembl1176,847,639 - 177,085,769 (-)Ensembl
GRCm381177,020,076 - 177,261,781 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,020,073 - 177,258,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,952,246 - 179,178,898 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,858,791 - 179,085,442 (-)NCBImm8
Celera1184,083,831 - 184,309,489 (-)NCBICelera
Cytogenetic Map1H4NCBI
Akt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21388,943,708 - 89,225,831 (-)NCBI
Rnor_6.0 Ensembl1395,081,390 - 95,348,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01395,076,308 - 95,348,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01399,527,953 - 99,800,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41392,802,390 - 93,110,704 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11393,002,743 - 93,299,588 (-)NCBI
Celera1388,523,410 - 88,791,412 (-)NCBICelera
Cytogenetic Map13q25NCBI
Akt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554066,907,876 - 7,163,672 (-)NCBIChiLan1.0ChiLan1.0
AKT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11224,480,762 - 224,824,950 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,480,784 - 224,824,838 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01219,107,482 - 219,463,140 (-)NCBIMhudiblu_PPA_v0panPan3
AKT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1734,633,064 - 34,931,112 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl734,636,124 - 34,931,112 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha734,110,532 - 34,416,684 (-)NCBI
ROS_Cfam_1.0734,462,499 - 34,769,046 (-)NCBI
UMICH_Zoey_3.1734,299,283 - 34,606,536 (-)NCBI
UNSW_CanFamBas_1.0734,316,186 - 34,622,902 (-)NCBI
UU_Cfam_GSD_1.0734,580,988 - 34,887,190 (-)NCBI
AKT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1016,441,447 - 16,741,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11016,441,465 - 16,741,745 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21017,966,073 - 18,268,805 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AKT3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12580,509,701 - 80,878,792 (-)NCBI
ChlSab1.1 Ensembl2580,515,168 - 80,816,018 (-)Ensembl
Vero_WHO_p1.0NW_02366605582,702,263 - 83,063,037 (-)NCBI
Akt3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477115,639,018 - 15,896,590 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005326569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040277173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005730451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005326569   ⟹   XP_005326626
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,867 (-)NCBI
SpeTri2.0NW_0049365266,944,056 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727203   ⟹   XP_021582878
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365267,045,459 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727204   ⟹   XP_021582879
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365267,045,458 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727206   ⟹   XP_021582881
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365267,055,406 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727207   ⟹   XP_021582882
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,240 (-)NCBI
SpeTri2.0NW_0049365266,944,056 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727208   ⟹   XP_021582883
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,686,863 (-)NCBI
SpeTri2.0NW_0049365267,045,457 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727209   ⟹   XP_021582884
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365267,054,771 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727210   ⟹   XP_021582885
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365267,036,327 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727211   ⟹   XP_021582886
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,767,922 (-)NCBI
SpeTri2.0NW_0049365266,979,334 - 7,201,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040277168   ⟹   XP_040133102
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,240 (-)NCBI
RefSeq Acc Id: XM_040277169   ⟹   XP_040133103
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,218 (-)NCBI
RefSeq Acc Id: XM_040277170   ⟹   XP_040133104
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,218 (-)NCBI
RefSeq Acc Id: XM_040277171   ⟹   XP_040133105
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,803,240 (-)NCBI
RefSeq Acc Id: XM_040277172   ⟹   XP_040133106
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,701,900 (-)NCBI
RefSeq Acc Id: XM_040277173   ⟹   XP_040133107
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,546,714 - 47,658,280 (-)NCBI
RefSeq Acc Id: XR_005730451
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934447,557,121 - 47,803,240 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005326626   ⟸   XM_005326569
- Peptide Label: isoform X1
- UniProtKB: I3MFT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582882   ⟸   XM_021727207
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021582886   ⟸   XM_021727211
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021582885   ⟸   XM_021727210
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021582883   ⟸   XM_021727208
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021582879   ⟸   XM_021727204
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582878   ⟸   XM_021727203
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582884   ⟸   XM_021727209
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021582881   ⟸   XM_021727206
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040133105   ⟸   XM_040277171
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040133102   ⟸   XM_040277168
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040133104   ⟸   XM_040277170
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040133103   ⟸   XM_040277169
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040133106   ⟸   XM_040277172
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040133107   ⟸   XM_040277173
- Peptide Label: isoform X7
Protein Domains
AGC-kinase C-terminal   PH   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010595 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000009513 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000030474 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010598 UniProtKB/TrEMBL
  ENSSTOT00000034960 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Akt3 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_PKB UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  RAC_gamma-like UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Akt3 ENTREZGENE
PANTHER PTHR24351:SF199 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A287DAB1_ICTTR UniProtKB/TrEMBL
  I3MFT2 ENTREZGENE, UniProtKB/TrEMBL