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Gene: Akt1 (AKT serine/threonine kinase 1) Rattus norvegicus
Symbol: Akt1
Name: AKT serine/threonine kinase 1
RGD ID: 2081
Description: Exhibits several functions, including ATP binding activity; GTPase activating protein binding activity; and enzyme binding activity. Involved in several processes, including cellular macromolecule biosynthetic process; cellular response to mechanical stimulus; and regulation of cellular protein metabolic process. Localizes to cytosol and nucleus. Used to study autosomal recessive polycystic kidney disease; hypertension; impotence; myocardial infarction; and type 2 diabetes mellitus. Biomarker of brain ischemia; paraplegia; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including Cowden syndrome; Proteus syndrome; breast cancer (multiple); pancreatic cancer (multiple); and prostate cancer (multiple). Orthologous to human AKT1 (AKT serine/threonine kinase 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; adenosine signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine.
Type: protein-coding
Also known as: Akt; AKT1 kinase; Murine thymoma viral (v-akt) oncogene homolog 1; PKB; PKB alpha; protein kinase B; protein kinase B alpha; RAC protein kinase alpha RAC-PK alpha; RAC protein kinase alpha, RAC-PK alpha; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1
Homo sapiens (human) : AKT1 (AKT serine/threonine kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Akt1 (thymoma viral proto-oncogene 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akt1 (AKT serine/threonine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKT1 (AKT serine/threonine kinase 1)
Canis lupus familiaris (dog) : AKT1 (AKT serine/threonine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akt1 (AKT serine/threonine kinase 1)
Sus scrofa (pig) : AKT1 (AKT serine/threonine kinase 1)
Chlorocebus sabaeus (African green monkey) : AKT1 (AKT serine/threonine kinase 1)
Heterocephalus glaber (naked mole-rat) : Akt1 (AKT serine/threonine kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06137,218,398 - 137,239,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,218,376 - 137,236,258 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06146,225,955 - 146,247,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46137,640,482 - 137,657,552 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16137,646,668 - 137,663,739 (-)NCBI
Celera6129,262,032 - 129,279,096 (-)NCBICelera
Cytogenetic Map6q32NCBI
RH 3.4 Map6782.49RGD
JBrowse: View Region in Genome Browser (JBrowse)