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Gene: Akt3 (thymoma viral proto-oncogene 3) Mus musculus
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Symbol: Akt3
Name: thymoma viral proto-oncogene 3
Description: Predicted to have ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of TOR signaling; positive regulation of cell size; and positive regulation of vasculature development. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma multiforme; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Is expressed in several structures, including heart; metanephros; nervous system; retina; and skin. Orthologous to human AKT3 (AKT serine/threonine kinase 3); PARTICIPATES IN altered phosphatidylinositol 3-kinase-Akt signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI851531; D930002M15Rik; Nmf350; PKB gamma; protein kinase Akt-3; protein kinase B gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma
Orthologs:
Homo sapiens (human) : AKT3 (AKT serine/threonine kinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Akt3 (AKT serine/threonine kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akt3 (AKT serine/threonine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AKT3 (AKT serine/threonine kinase 3)
Canis lupus familiaris (dog) : AKT3 (AKT serine/threonine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akt3 (AKT serine/threonine kinase 3)
Sus scrofa (pig) : AKT3 (AKT serine/threonine kinase 3)
Chlorocebus sabaeus (African green monkey) : AKT3 (AKT serine/threonine kinase 3)
Heterocephalus glaber (naked mole-rat) : Akt3 (AKT serine/threonine kinase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1177,020,073 - 177,258,203 (-)Ensembl
GRCm381177,020,076 - 177,261,781 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,952,246 - 179,178,898 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,858,791 - 179,085,442 (-)NCBImm8
Celera1184,083,831 - 184,309,489 (-)NCBICelera
Cytogenetic Map1 H4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Akt3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62395
Created: 2001-04-26
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.