LOC102556096 (pyrin domain-containing protein 3-like) - Rat Genome Database

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Advanced Search (OLGA)
Gene: LOC102556096 (pyrin domain-containing protein 3-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC102556096
Name: pyrin domain-containing protein 3-like
RGD ID: 7636450
Description: Predicted to enable double-stranded DNA binding activity. Predicted to be involved in activation of innate immune response and cellular response to interferon-beta. Predicted to be active in cytosol and nucleoplasm. Orthologous to human IFI16 (interferon gamma inducible protein 16).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mucin-5AC-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81388,444,247 - 88,461,817 (-)NCBIGRCr8
mRatBN7.21385,911,915 - 85,929,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1385,912,044 - 85,929,007 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01391,977,441 - 91,981,426 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,980,114 - 91,981,432 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01396,495,234 - 96,496,632 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1385,514,943 - 85,532,454 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC102556096Ratactivation of innate immune response involved_inIEAInterPro:IPR0402051600115GO_REF:0000002InterProGO_REF:0000002
LOC102556096Ratactivation of innate immune response involved_inIBAMGI:2686159 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC102556096Ratcellular response to interferon-beta involved_inIBAMGI:101847 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC102556096Ratcellular response to interferon-beta involved_inIEAInterPro:IPR0402051600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC102556096Ratcytosol is_active_inIBAMGI:2686159 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC102556096Ratnucleoplasm is_active_inIBAPANTHER:PTN001385751 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC102556096Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC102556096Ratdouble-stranded DNA binding enablesIBAMGI:101847 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in LOC102556096
116 total Variants

Predicted Target Of
Summary Value
Count of predictions:10
Count of miRNA genes:9
Interacting mature miRNAs:10
Transcripts:ENSRNOT00000004637
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat

1 to 10 of 21 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 41 56 89 88 57 25 57 6 197 89 36 34 49 31



Ensembl Acc Id: ENSRNOT00000004637   ⟹   ENSRNOP00000004637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1391,980,114 - 91,981,432 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114090   ⟹   ENSRNOP00000089486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1385,912,044 - 85,929,007 (-)Ensembl
RefSeq Acc Id: XM_039091428   ⟹   XP_038947356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,444,247 - 88,461,817 (-)NCBI
mRatBN7.21385,911,915 - 85,929,490 (-)NCBI
RefSeq Acc Id: XM_039091429   ⟹   XP_038947357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,444,247 - 88,461,328 (-)NCBI
mRatBN7.21385,911,915 - 85,928,997 (-)NCBI
RefSeq Acc Id: XM_039091430   ⟹   XP_038947358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,444,247 - 88,461,342 (-)NCBI
mRatBN7.21385,911,915 - 85,928,662 (-)NCBI
RefSeq Acc Id: XM_039091431   ⟹   XP_038947359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,444,247 - 88,461,817 (-)NCBI
mRatBN7.21385,911,915 - 85,929,491 (-)NCBI
RefSeq Acc Id: XM_063272721   ⟹   XP_063128791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,444,247 - 88,461,328 (-)NCBI
Protein RefSeqs XP_038947356 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947357 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947358 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947359 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128791 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089486
  ENSRNOP00000089486.1
Ensembl Acc Id: ENSRNOP00000004637   ⟸   ENSRNOT00000004637
RefSeq Acc Id: XP_038947359   ⟸   XM_039091431
- UniProtKB: A0A8I6A8B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947356   ⟸   XM_039091428
- UniProtKB: A0A8I6A8B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947357   ⟸   XM_039091429
- UniProtKB: A0A8I6A8B1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947358   ⟸   XM_039091430
- UniProtKB: A0A8I6A8B1 (UniProtKB/TrEMBL)
HIN-200   Pyrin

Name Modeler Protein Id AA Range Protein Structure
AF-F1M0K4-F1-model_v2 AlphaFold F1M0K4 1-134 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17273 BioCyc
Ensembl Genes ENSRNOG00000042990 Ensembl
  ENSRNOG00000065208 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000114090 ENTREZGENE
  ENSRNOT00000114090.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
InterPro DAPIN UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  HIN-200 UniProtKB/TrEMBL
  HIN200/IF120x UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
NCBI Gene LOC102556096 ENTREZGENE
PANTHER INTEFERON-ACTIVABLE PROTEIN 208-RELATED UniProtKB/TrEMBL
  PTHR12200 UniProtKB/TrEMBL
Pfam HIN UniProtKB/TrEMBL
  PYRIN UniProtKB/TrEMBL
PhenoGen LOC102556096 PhenoGen
PROSITE DAPIN UniProtKB/TrEMBL
  HIN_200 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042990 RatGTEx
  ENSRNOG00000065208 RatGTEx
SMART PYRIN UniProtKB/TrEMBL
Superfamily-SCOP HIN-2000 domain-like UniProtKB/TrEMBL
UniProt A0A8I6A8B1 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-12-18 LOC102556096  pyrin domain-containing protein 3-like      Symbol and Name status set to provisional 70820 PROVISIONAL