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Gene: Fcgr2a (Fc fragment of IgG receptor IIa) Rattus norvegicus
Symbol: Fcgr2a
Name: Fc fragment of IgG receptor IIa
RGD ID: 71069
Description: Exhibits immunoglobulin receptor binding activity. Involved in several processes, including regulation of Fc-gamma receptor signaling pathway involved in phagocytosis; regulation of antibody-dependent cellular cytotoxicity; and regulation of tumor necrosis factor production. Localizes to cell surface. Used to study crescentic glomerulonephritis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc fragment of IgG receptor IIa); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; Leishmaniasis pathway; phagocytosis pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.
Type: protein-coding
Also known as: Fc fragment of IgG low affinity IIa receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc receptor, IgG, low affinity III; fc-gamma RIII; Fcgr3; Fcgr3a; fcRIII; igG Fc receptor III; LOC360876; low affinity immunoglobulin gamma Fc region receptor III
Homo sapiens (human) : FCGR2A (Fc fragment of IgG receptor IIa)  HGNC  Alliance
Mus musculus (house mouse) : Fcgr3 (Fc receptor, IgG, low affinity III)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FCGR2A (Fc fragment of IgG receptor IIa)
Chlorocebus sabaeus (African green monkey) : FCGR2A (Fc fragment of IgG receptor IIa)
Heterocephalus glaber (naked mole-rat) : Fcgr2a (Fc fragment of IgG receptor IIa)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01391,146,878 - 91,163,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,146,876 - 91,229,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,168,973 - 91,198,036 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,665,044 - 95,682,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,898,651 - 86,911,743NCBIRGSC3.4rn4RGSC3.4
Celera1382,933,510 - 83,125,911 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fcgr2a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71069
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.