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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcgr2a
Name: Fc gamma receptor 2A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcgr2adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FCGR2A mRNAPMID:30816183 PMID:32528016 PMID:34947998
Fcgr2aincreases expressionEXP 6480464CTDbisphenol A results in increased expression of FCGR2A mRNAPMID:25181051
Fcgr2amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of FCGR2A promoterPMID:23359474
Fcgr2aincreases expressionISOFcgr3 (Mus musculus)6480464CTDbisphenol A results in increased expression of FCGR3 mRNAPMID:29248573 PMID:34585602
Fcgr2amultiple interactionsISOFCGR2A (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of FCGR2A genePMID:31601247
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