Fcgr2a (Fc fragment of IgG receptor IIa) - Rat Genome Database

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Gene: Fcgr2a (Fc fragment of IgG receptor IIa) Ictidomys tridecemlineatus
Analyze
Symbol: Fcgr2a
Name: Fc fragment of IgG receptor IIa
RGD ID: 12450753
Description: ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101954523; low affinity immunoglobulin gamma Fc region receptor II-a; low affinity immunoglobulin gamma Fc region receptor III-like; low affinity immunoglobulin gamma Fc region receptor III-like, transcript variant X1; low affinity immunoglobulin gamma Fc region receptor III-like, transcript variant X2
RGD Orthologs
Human
Rat
Bonobo
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,496,110 - 7,502,712 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493713115,542 - 22,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Fcgr2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,496,110 - 7,502,712 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493713115,542 - 22,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCGR2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,505,457 - 161,524,048 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,505,430 - 161,524,013 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,475,247 - 161,489,619 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,741,844 - 159,755,984 (+)NCBINCBI36Build 36hg18NCBI36
Build 341158,288,274 - 158,302,415NCBI
Celera1134,591,741 - 134,592,404 (-)NCBICelera
Celera1134,682,428 - 134,687,972 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,800,353 - 132,814,372 (+)NCBIHuRef
CHM1_11162,897,042 - 162,911,192 (+)NCBICHM1_1
T2T-CHM13v2.01160,768,080 - 160,786,676 (+)NCBIT2T-CHM13v2.0
Fcgr2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,813,516 - 85,830,269 (-)NCBIGRCr8
mRatBN7.21383,280,782 - 83,297,535 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,280,784 - 83,295,967 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1385,900,776 - 85,913,853 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,194,261 - 87,207,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,432,186 - 84,445,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01391,146,878 - 91,163,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,168,973 - 91,198,036 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,146,876 - 91,229,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,665,044 - 95,682,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,898,651 - 86,911,743NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1382,933,510 - 83,125,911 (-)NCBICelera
Cytogenetic Map13q24NCBI
LOC100991644
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,268,426 - 88,282,501 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1187,936,861 - 87,950,937 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,892,311 - 136,906,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FCGR2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,480,710 - 2,512,429 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660381,557,192 - 1,570,636 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcgr2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462482623,930 - 34,735 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005342539   ⟹   XP_005342596
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244050587,496,110 - 7,502,712 (+)NCBI
SpeTri2.0NW_00493713115,542 - 22,099 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013366312   ⟹   XP_013221766
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244050587,496,114 - 7,502,712 (+)NCBI
SpeTri2.0NW_00493713115,542 - 22,099 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005342596 (Get FASTA)   NCBI Sequence Viewer  
  XP_013221766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004145.3
GenBank Protein KAG3281125 (Get FASTA)   NCBI Sequence Viewer  
  KAG3281126 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005342596   ⟸   XM_005342539
- Peptide Label: isoform X1
- UniProtKB: I3M4K7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013221766   ⟸   XM_013366312
- Peptide Label: isoform X2
- Sequence:
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004625 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004619.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
NCBI Gene LOC101954523 ENTREZGENE
PANTHER IMMUNOGLOBULIN FC RECEPTOR UniProtKB/TrEMBL
  LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-B-RELATED UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt I3M4K7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 Fcgr2a  Fc fragment of IgG receptor IIa  LOC101954523  low affinity immunoglobulin gamma Fc region receptor III-like  Symbol and/or name change 5135510 APPROVED