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Gene: Fcgr3 (Fc receptor, IgG, low affinity III) Mus musculus
Symbol: Fcgr3
Name: Fc receptor, IgG, low affinity III
Description: Exhibits IgG binding activity and IgG receptor activity. Involved in several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including arthritis (multiple); autoimmune hypersensitivity disease (multiple); dengue disease (multiple); hematologic cancer (multiple); and leukopenia (multiple). Is expressed in liver and spleen. Orthologous to several human genes including FCGR2A (Fc fragment of IgG receptor IIa); PARTICIPATES IN Leishmaniasis pathway; Staphylococcus aureus infection pathway; systemic lupus erythematosus pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD16; Fc gamma receptor III; fc-gamma RIII; Fcg receptor III; FcgammaRIII; fcRIII; igG Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III
Homo sapiens (human) : FCGR2A (Fc fragment of IgG receptor IIa)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fcgr2a (Fc fragment of IgG receptor IIa)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FCGR2A (Fc fragment of IgG receptor IIa)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1171,051,174 - 171,064,935 (-)Ensembl
GRCm381171,051,169 - 171,065,915 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,981,300 - 172,989,534 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,887,870 - 172,896,073 (-)NCBImm8
Celera1173,499,171 - 173,507,755 (-)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map178.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fcgr3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736451
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.