Fcgr3 (Fc receptor, IgG, low affinity III) - Rat Genome Database

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Gene: Fcgr3 (Fc receptor, IgG, low affinity III) Mus musculus
Analyze
Symbol: Fcgr3
Name: Fc receptor, IgG, low affinity III
RGD ID: 736451
MGI Page MGI
Description: Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD16; Fc gamma receptor III; fc-gamma RIII; Fcg receptor III; Fcgam; FcgammaRIII; fcRIII; igG Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III
RGD Orthologs
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,878,738 - 170,893,477 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,878,743 - 170,892,504 (-)EnsemblGRCm39 Ensembl
GRCm381171,051,169 - 171,065,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,051,174 - 171,064,935 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,981,300 - 172,989,534 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,887,870 - 172,896,073 (-)NCBIMGSCv36mm8
Celera1173,499,171 - 173,507,755 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map178.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3,5-trinitro-1,3,5-triazinane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-nitrofluorene  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
benzo[a]pyrene  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
captan  (EXP)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (EXP,ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
diuron  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
fipronil  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
gentamycin  (ISO)
hexachlorobenzene  (ISO)
isoprenaline  (EXP)
L-methionine  (EXP)
lipopolysaccharide  (EXP)
mercury dichloride  (EXP)
methotrexate  (EXP)
methylmercury chloride  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nimesulide  (ISO)
nitrofen  (ISO)
oxycodone  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
SCH 23390  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
Soman  (ISO)
streptozocin  (ISO)
sulpiride  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
tremolite asbestos  (EXP)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
tungsten  (EXP)
undecane  (ISO)
ursolic acid  (EXP)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Fc(epsilon)RI and FcgammaRIII/CD16 differentially regulate atopic dermatitis in mice. Abboud G, etal., J Immunol. 2009 May 15;182(10):6517-26.
2. Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Aitman TJ, etal., Nature. 2006 Feb 16;439(7078):851-5.
3. FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis. Andren M, etal., Scand J Immunol. 2006 Apr;63(4):282-9.
4. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Asano K, etal., Nat Genet. 2009 Dec;41(12):1325-9. Epub 2009 Nov 15.
5. Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. Baudino L, etal., J Immunol. 2008 Feb 1;180(3):1948-53.
6. Fc gamma RIIa polymorphism: a susceptibility factor for immune complex-mediated lupus nephritis in Brazilian patients. Bazilio AP, etal., Nephrol Dial Transplant. 2004 Jun;19(6):1427-31. Epub 2004 Mar 5.
7. Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII. Boross P, etal., J Immunol. 2008 Apr 1;180(7):5083-91.
8. On the role of platelet Fc gamma RIIa phenotype in heparin-induced thrombocytopenia. Brandt JT, etal., Thromb Haemost. 1995 Dec;74(6):1564-72.
9. Common variants in genes that mediate immunity and risk of multiple myeloma. Brown EE, etal., Int J Cancer. 2007 Jun 15;120(12):2715-22.
10. Associations between Fc gamma receptor IIA polymorphisms and the risk and prognosis of meningococcal disease. Domingo P, etal., Am J Med. 2002 Jan;112(1):19-25.
11. Effect of FCGR2A and FCGR3A variants on CLL outcome. Dornan D, etal., Blood. 2010 Nov 18;116(20):4212-22. doi: 10.1182/blood-2010-03-272765. Epub 2010 Aug 12.
12. The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A. Eckhardt CL, etal., J Thromb Haemost. 2014 Aug;12(8):1294-301. doi: 10.1111/jth.12631. Epub 2014 Jul 16.
13. FcgammaRIIa and FcgammaRIIIa genetic polymorphisms in a group of pediatric immune thrombocytopenic purpura in Egypt. Eyada TK, etal., Blood Coagul Fibrinolysis. 2012 Jan;23(1):64-8. doi: 10.1097/MBC.0b013e32834ddf2f.
14. The role of Fcgamma receptor polymorphisms and C3 in the immune defence against Neisseria meningitidis in complement-deficient individuals. Fijen CA, etal., Clin Exp Immunol. 2000 May;120(2):338-45.
15. [Low-affinity Fcgamma receptor IIa gene polymorphism and dengue bleeding disorder]. Garcia G, etal., Enferm Infecc Microbiol Clin. 2012 Dec;30(10):621-3. doi: 10.1016/j.eimc.2012.05.011. Epub 2012 Jul 18.
16. FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: a meta-analysis on 1134 patients from two prospective cohorts. Ghesquieres H, etal., Hematol Oncol. 2016 Jun 10. doi: 10.1002/hon.2305.
17. Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. Giorgini A, etal., J Immunol. 2008 Dec 15;181(12):8745-52.
18. Dendritic cells modulate platelet activity in IVIg-mediated amelioration of ITP in mice. Huang HS, etal., Blood. 2010 Dec 2;116(23):5002-9. doi: 10.1182/blood-2010-03-275123. Epub 2010 Aug 10.
19. Activating Fc gamma receptors participate in the development of autoimmune diabetes in NOD mice. Inoue Y, etal., J Immunol. 2007 Jul 15;179(2):764-74.
20. Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes. Jonsen A, etal., Rheumatology (Oxford). 2007 Sep;46(9):1417-21. Epub 2007 Jun 27.
21. Decreased expression of both Fc gamma RII and Fc gamma RIII mRNA in leukemic granulocytes. Kant A, etal., Leuk Res. 1995 Dec;19(12):997-1000.
22. Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the Fc gamma receptor IIA. Kim YS, etal., Blood Coagul Fibrinolysis. 2009 Jul;20(5):353-7.
23. Inhibition of hyperacute transplant rejection by soluble proteins with the functional domains of CD46 and FcgammaRII. Lanteri MB, etal., Transplantation. 2000 Mar 27;69(6):1128-36.
24. Susceptibility for ischemic stroke in four constitution medicine is associated with polymorphisms of FCGR2A and IL1RN genes. Lee BC, etal., Neurol Res. 2010 Feb;32 Suppl 1:43-7.
25. FCGR3A and FCGR2A polymorphisms may not correlate with response to alemtuzumab in chronic lymphocytic leukemia. Lin TS, etal., Blood. 2005 Jan 1;105(1):289-91. Epub 2004 Jun 24.
26. High-dose dexamethasone shifts the balance of stimulatory and inhibitory Fcgamma receptors on monocytes in patients with primary immune thrombocytopenia. Liu XG, etal., Blood. 2011 Feb 10;117(6):2061-9. doi: 10.1182/blood-2010-07-295477. Epub 2010 Dec 3.
27. The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model. McKenzie SE, etal., J Immunol. 1999 Apr 1;162(7):4311-8.
28. FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia. Meyer D, etal., Blood. 1998 Dec 1;92(11):3997-4002.
29. CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice. Meyer T, etal., Blood. 2015 Nov 5;126(19):2230-8. doi: 10.1182/blood-2015-04-638684. Epub 2015 Sep 22.
30. Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice. Meyer T, etal., J Thromb Haemost. 2009 Jan;7(1):171-81. doi: 10.1111/j.1538-7836.2008.03212.x. Epub 2008 Oct 30.
31. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
32. MGDs mouse GO annotations MGD data from the GO Consortium
33. MGD IEA MGD IEA
34. Association of Fc¿RIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan. Mohsin SN, etal., Am J Trop Med Hyg. 2015 Oct;93(4):691-6. doi: 10.4269/ajtmh.15-0199. Epub 2015 Aug 3.
35. [The diagnostic of defects of inborn immunity under B-cell tumors of lymphatic system]. Nazarova EL, etal., Klin Lab Diagn. 2014 Nov;59(11):39-42.
36. Relationship between Fc receptor IIA polymorphism and infection in children with sickle cell disease. Norris CF, etal., J Pediatr. 1996 Jun;128(6):813-9.
37. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
38. Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases. Ozturk C, etal., Clin Exp Med. 2006 Mar;6(1):27-32.
39. Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis. Page TH, etal., J Biol Chem. 2012 Feb 17;287(8):5710-9. doi: 10.1074/jbc.M111.260695. Epub 2011 Dec 19.
40. FcgammaRIIa and FcgammaRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcome. Papagianni A, etal., Blood Coagul Fibrinolysis. 2013 Jan;24(1):35-9. doi: 10.1097/MBC.0b013e328359bc3b.
41. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Pedotti R, etal., Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1867-72. Epub 2003 Feb 7.
42. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
43. Mouse MP Annotation Import Pipeline RGD automated import pipeline
44. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
45. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
46. FcgammaRIII is protective against Pseudomonas aeruginosa pneumonia. Rhein LM, etal., Am J Respir Cell Mol Biol. 2008 Apr;38(4):401-6. Epub 2007 Nov 1.
47. Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Sanchez E, etal., Ann Rheum Dis. 2011 Jun 30.
48. FCGR2A functional genetic variant associated with susceptibility to severe malarial anaemia in Ghanaian children. Schuldt K, etal., J Med Genet. 2010 Jul;47(7):471-5. Epub 2009 Dec 3.
49. Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Sinha S, etal., Malar J. 2008 Jan 14;7:13.
50. The Fcgamma receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia. Sole-Violan J, etal., Crit Care Med. 2011 Jun;39(6):1388-93.
51. A single-nucleotide polymorphism of the Fcgamma receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies. Takami A, etal., Bone Marrow Transplant. 2011 Feb;46(2):238-43. doi: 10.1038/bmt.2010.88. Epub 2010 Apr 19.
52. FcgammaRIII b and FcgammaRIIa polymorphism may affect the production of specific NA1 autoantibody and clinical course of autoimmune neutropenia of infancy. Taniuchi S, etal., Hum Immunol. 2001 Apr;62(4):408-13.
53. A novel splice variant of FcgammaRIIa: a risk factor for anaphylaxis in patients with hypogammaglobulinemia. van der Heijden J, etal., J Allergy Clin Immunol. 2013 May;131(5):1408-16.e5. doi: 10.1016/j.jaci.2013.02.009. Epub 2013 Mar 29.
54. A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice. van Royen-Kerkhof A, etal., Br J Haematol. 2005 Jul;130(1):130-7.
55. Expression of genes encoding receptors for IgG (FcRIII) and for C3b/C4b (Crry) in rat sciatic nerve during development and Wallerian degeneration. Vedeler CA, etal., J Neurosci Res. 1992 Apr;31(4):654-61.
56. Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations. Weersma RK, etal., Inflamm Bowel Dis. 2010 Dec;16(12):2080-9. doi: 10.1002/ibd.21342.
57. Correlation of Fc(gamma)RIIa (CD32) Polymorphism and IgG Antibody Subclasses in Hemolytic Disease of Newborn. Wu Q, etal., Neonatology. 2009;96(1):1-5. doi: 10.1159/000189239. Epub 2009 Jan 8.
Additional References at PubMed
PMID:1301170   PMID:1358808   PMID:1372955   PMID:1386873   PMID:2138787   PMID:2139735   PMID:2476388   PMID:2498841   PMID:2570566   PMID:2574151   PMID:2591369   PMID:2787796  
PMID:2894402   PMID:2946078   PMID:2971731   PMID:3384439   PMID:3416634   PMID:7636231   PMID:7664793   PMID:8069908   PMID:8070412   PMID:8313472   PMID:8552190   PMID:8642269  
PMID:8769481   PMID:9143687   PMID:9200458   PMID:9653099   PMID:9743367   PMID:10051626   PMID:10229794   PMID:10330436   PMID:10349636   PMID:10395649   PMID:10397164   PMID:10464288  
PMID:10550549   PMID:10572101   PMID:10623857   PMID:10640769   PMID:10693874   PMID:10770797   PMID:10842103   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11237803  
PMID:11283678   PMID:11290803   PMID:11420040   PMID:11733380   PMID:11869678   PMID:11911824   PMID:11983693   PMID:12055255   PMID:12355445   PMID:12389094   PMID:12421967   PMID:12427132  
PMID:12444173   PMID:12466851   PMID:12477718   PMID:12477932   PMID:12488432   PMID:12528127   PMID:12626560   PMID:12682266   PMID:12705859   PMID:12707052   PMID:12794146   PMID:12898452  
PMID:12941957   PMID:12960309   PMID:12969160   PMID:14643301   PMID:14742542   PMID:15112102   PMID:15197227   PMID:15210744   PMID:15265942   PMID:15316030   PMID:15466618   PMID:15661880  
PMID:15664957   PMID:15728518   PMID:15831698   PMID:15878887   PMID:15880819   PMID:15921521   PMID:16039578   PMID:16141072   PMID:16141073   PMID:16184517   PMID:16278814   PMID:16301658  
PMID:16322460   PMID:16418399   PMID:16428769   PMID:16444258   PMID:16452176   PMID:16453025   PMID:16493085   PMID:16498503   PMID:16513171   PMID:16520392   PMID:16585547   PMID:16627486  
PMID:16836651   PMID:16917543   PMID:16920981   PMID:17053192   PMID:17182584   PMID:17182587   PMID:17239631   PMID:17273841   PMID:17277081   PMID:17328787   PMID:17475849   PMID:17558411  
PMID:17664287   PMID:17767162   PMID:17934470   PMID:17956862   PMID:18063701   PMID:18070890   PMID:18097064   PMID:18463609   PMID:18495955   PMID:18604868   PMID:18715866   PMID:18768867  
PMID:18776906   PMID:18949059   PMID:19008955   PMID:19060331   PMID:19360001   PMID:19395450   PMID:19435903   PMID:19447681   PMID:19503602   PMID:19720605   PMID:19795417   PMID:19951957  
PMID:19996316   PMID:20074624   PMID:20148421   PMID:20300179   PMID:20368175   PMID:20410215   PMID:20484044   PMID:20494341   PMID:20566342   PMID:20974962   PMID:21037092   PMID:21135140  
PMID:21169548   PMID:21187373   PMID:21248252   PMID:21308776   PMID:21317388   PMID:21724994   PMID:21746933   PMID:21873635   PMID:22025304   PMID:22025730   PMID:22138510   PMID:22278120  
PMID:22285694   PMID:22290146   PMID:22337713   PMID:22366371   PMID:22387002   PMID:22415018   PMID:22430937   PMID:22474370   PMID:22493083   PMID:22502635   PMID:22845035   PMID:22908282  
PMID:22908332   PMID:22930820   PMID:23112187   PMID:23150715   PMID:23183896   PMID:23303673   PMID:23345428   PMID:23345431   PMID:23585480   PMID:23740955   PMID:23744294   PMID:23754379  
PMID:23897981   PMID:23903009   PMID:23916706   PMID:24008160   PMID:24166713   PMID:24166714   PMID:24218606   PMID:24356538   PMID:24412922   PMID:24509813   PMID:24523933   PMID:24752483  
PMID:25038257   PMID:25043618   PMID:25136095   PMID:25740324   PMID:25783751   PMID:25824719   PMID:25904149   PMID:26208901   PMID:26216934   PMID:26373277   PMID:26451966   PMID:26621863  
PMID:26627823   PMID:26643908   PMID:26787820   PMID:27059595   PMID:27082928   PMID:27226142   PMID:27265505   PMID:27297794   PMID:27403737   PMID:27555460   PMID:27622332   PMID:27847322  
PMID:28512240   PMID:28532839   PMID:28539825   PMID:28756234   PMID:29523656   PMID:29597194   PMID:30779858   PMID:31196979   PMID:31534958   PMID:31801071   PMID:32195245   PMID:33168576  
PMID:33244759   PMID:34818534   PMID:35320345   PMID:36189253   PMID:36913025   PMID:37520575   PMID:38018994   PMID:38314895   PMID:38355793  


Genomics

Comparative Map Data
Fcgr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,878,738 - 170,893,477 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,878,743 - 170,892,504 (-)EnsemblGRCm39 Ensembl
GRCm381171,051,169 - 171,065,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,051,174 - 171,064,935 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,981,300 - 172,989,534 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,887,870 - 172,896,073 (-)NCBIMGSCv36mm8
Celera1173,499,171 - 173,507,755 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map178.8NCBI
Fcgr2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81385,813,516 - 85,830,269 (-)NCBIGRCr8
mRatBN7.21383,280,782 - 83,297,535 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,280,784 - 83,295,967 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1385,900,776 - 85,913,853 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,194,261 - 87,207,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,432,186 - 84,445,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01391,146,878 - 91,163,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,168,973 - 91,198,036 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,146,876 - 91,229,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,665,044 - 95,682,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41386,898,651 - 86,911,743NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1382,933,510 - 83,125,911 (-)NCBICelera
Cytogenetic Map13q24NCBI

Variants

.
Variants in Fcgr3
718 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:545
Count of miRNA genes:318
Interacting mature miRNAs:346
Transcripts:ENSMUST00000164044, ENSMUST00000164179, ENSMUST00000168817, ENSMUST00000169017
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139452188173452308Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139602037173602216Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139602037173602216Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139602037173602216Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139602037173602216Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139602037173602216Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139602037173602216Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139602037173602216Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139602037173602216Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141095010175095156Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141233173175233272Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141233173175233272Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141233173175233272Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141233173175233272Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142489543176489734Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143284665177284803Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144449142178449142Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144531347178531592Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145077630179077630Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145145207179145325Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147125258171632257Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147125258182873798Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147125258188983224Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147219390181219390Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147219390181219390Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9147875502181875616Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1147875502181875616Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150193673188359312Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150193673188359312Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150193673188359312Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150756737184756922Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151186243185186402Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined151835111185835280Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152038741186038913Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152038741186038913Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152038741186038913Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152038741186038913Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152038741186038913Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152132744186132744Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152132744186132744Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152794822186438620Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153557406175468938Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153675990187676105Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153712853187712853Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154410512188410512Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155002940189002940Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155002940189002940Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155002940189002940Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155525623189527533Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155526796189526897Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155582237185994196Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155716221189716369Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155716221189716369Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155716221189716369Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155721528189722608Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1155831765189831892Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined155831765189831892Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1155831765189831892Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1155831765189831892Mouse
13452393Ity3b_mimmunity to S. typhimurium 3b (mouse)1156497439172097436Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156602037176262693Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156602037189303617Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156602037189303617Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157456299191456436Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157456299191456436Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157456299191456436Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157456299191456436Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157456299191456436Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157456299191456436Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157456299191456436Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158468817192468938Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158468817192468938Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158468817192468938Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158468817192468938Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158468817192468938Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158468817192468938Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159262573193262693Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160097157194097157Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160097157194097157Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160112768194112883Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161201261195154279Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162145207194111528Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1162977097185994196Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164143227190534272Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1165873675195154279Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167462514195154279Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167462514195154279Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167462514195154279Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167586086191225397Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167756737189303617Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1167954584195154279Mouse
1302037Nktcn1_mnatural killer T cell numbers 1 (mouse)Not determined1168186243171632257Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168213823195154279Mouse
4142065Bmd5b_mbone mineral density 5b (mouse)Not determined168835111171765633Mouse
10412205Bbaa30_mB.burgdorferi-associated arthritis 30 (mouse)Not determined1169038741174456436Mouse
1357854Sle16_msystematic lupus erythematosus susceptibility 16 (mouse)Not determined1169038741177377587Mouse
13207571Tcq11_mtotal cholesterol QTL 11 (mouse)1169137569179647565Mouse
13207587Mwmlpt1_mMorris water maze latency to platform, training, 1 (mouse)1169597438173397435Mouse
13207591Mwmlpa1_mMorris water maze latency to platform, all, 1 (mouse)1169797438173297435Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170379500195154279Mouse
38456000Lick2_mlick rate 2, sucralose (mouse)1170397438173397435Mouse
38456001Lick1_mlick rate 1, water (mouse)1170397438173397435Mouse
1302201Alcw1_malcohol withdrawal 1 (mouse)Not determined1170868354171966357Mouse
1301016Szs1_mseizure susceptibility 1 (mouse)Not determined1170878743174456436Mouse
4141878Qrr1_mQTL rich region on chromosome 1 (mouse)Not determined170878743175320066Mouse

Markers in Region
M14215  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381171,051,386 - 171,051,476UniSTSGRCm38
MGSCv371172,981,517 - 172,981,607UniSTSGRCm37
Celera1173,499,398 - 173,499,488UniSTS
Cytogenetic Map1H3UniSTS
cM Map192.3UniSTS
Whitehead/MRC_RH12123.41UniSTS
Fcgr3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H3UniSTS
cM Map192.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006496659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC117796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF197930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY897429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY199827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U11854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000164044   ⟹   ENSMUSP00000131938
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,878,744 - 170,886,972 (-)Ensembl
GRCm38.p6 Ensembl1171,051,175 - 171,059,403 (-)Ensembl
RefSeq Acc Id: ENSMUST00000164179   ⟹   ENSMUSP00000133039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,885,397 - 170,892,504 (-)Ensembl
GRCm38.p6 Ensembl1171,057,828 - 171,064,935 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168817
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,878,743 - 170,885,623 (-)Ensembl
GRCm38.p6 Ensembl1171,051,174 - 171,058,054 (-)Ensembl
RefSeq Acc Id: ENSMUST00000169017   ⟹   ENSMUSP00000131836
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,878,764 - 170,886,972 (-)Ensembl
GRCm38.p6 Ensembl1171,051,195 - 171,059,403 (-)Ensembl
RefSeq Acc Id: NM_001356511   ⟹   NP_001343440
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,738 - 170,892,496 (-)NCBI
GRCm381171,051,169 - 171,059,394 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001405018   ⟹   NP_001391947
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,738 - 170,892,496 (-)NCBI
RefSeq Acc Id: NM_001405019   ⟹   NP_001391948
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,738 - 170,893,477 (-)NCBI
RefSeq Acc Id: NM_010188   ⟹   NP_034318
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,738 - 170,886,972 (-)NCBI
GRCm381171,051,169 - 171,059,403 (-)NCBI
MGSCv371172,981,300 - 172,989,534 (-)RGD
Celera1173,499,171 - 173,507,755 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496659   ⟹   XP_006496722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,747 - 170,893,476 (-)NCBI
GRCm381171,051,178 - 171,065,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247708   ⟹   XP_030103568
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,878,747 - 170,889,052 (-)NCBI
GRCm381171,051,178 - 171,061,483 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001343440 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391947 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391948 (Get FASTA)   NCBI Sequence Viewer  
  NP_034318 (Get FASTA)   NCBI Sequence Viewer  
  XP_006496722 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103568 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37604 (Get FASTA)   NCBI Sequence Viewer  
  AAC18428 (Get FASTA)   NCBI Sequence Viewer  
  AAG28520 (Get FASTA)   NCBI Sequence Viewer  
  AAH52819 (Get FASTA)   NCBI Sequence Viewer  
  AAX13974 (Get FASTA)   NCBI Sequence Viewer  
  AAX13975 (Get FASTA)   NCBI Sequence Viewer  
  AAX13976 (Get FASTA)   NCBI Sequence Viewer  
  AAX13977 (Get FASTA)   NCBI Sequence Viewer  
  AAX13978 (Get FASTA)   NCBI Sequence Viewer  
  AAX13979 (Get FASTA)   NCBI Sequence Viewer  
  AAX13980 (Get FASTA)   NCBI Sequence Viewer  
  AAX13981 (Get FASTA)   NCBI Sequence Viewer  
  AAX13982 (Get FASTA)   NCBI Sequence Viewer  
  AAX13983 (Get FASTA)   NCBI Sequence Viewer  
  AAX13984 (Get FASTA)   NCBI Sequence Viewer  
  BAC36696 (Get FASTA)   NCBI Sequence Viewer  
  BAE30502 (Get FASTA)   NCBI Sequence Viewer  
  BAE30695 (Get FASTA)   NCBI Sequence Viewer  
  BAE31560 (Get FASTA)   NCBI Sequence Viewer  
  BAE31949 (Get FASTA)   NCBI Sequence Viewer  
  BAE32004 (Get FASTA)   NCBI Sequence Viewer  
  BAE32906 (Get FASTA)   NCBI Sequence Viewer  
  BAE35482 (Get FASTA)   NCBI Sequence Viewer  
  BAE42371 (Get FASTA)   NCBI Sequence Viewer  
  CAA43266 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000131836
  ENSMUSP00000131836.2
  ENSMUSP00000131938
  ENSMUSP00000131938.2
  ENSMUSP00000133039.2
GenBank Protein P08508 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034318   ⟸   NM_010188
- Peptide Label: isoform 1 precursor
- UniProtKB: A0A0B4J1M6 (UniProtKB/TrEMBL),   Q9ES92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006496722   ⟸   XM_006496659
- Peptide Label: isoform X1
- UniProtKB: A0A0B4J1M6 (UniProtKB/TrEMBL),   Q9ES92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343440   ⟸   NM_001356511
- Peptide Label: isoform 2 precursor
- UniProtKB: E9PUV2 (UniProtKB/TrEMBL),   Q9ES92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030103568   ⟸   XM_030247708
- Peptide Label: isoform X1
- UniProtKB: A0A0B4J1M6 (UniProtKB/TrEMBL),   Q9ES92 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000131938   ⟸   ENSMUST00000164044
RefSeq Acc Id: ENSMUSP00000133039   ⟸   ENSMUST00000164179
RefSeq Acc Id: ENSMUSP00000131836   ⟸   ENSMUST00000169017
RefSeq Acc Id: NP_001391948   ⟸   NM_001405019
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9ES92 (UniProtKB/TrEMBL),   A0A0B4J1M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001391947   ⟸   NM_001405018
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9ES92 (UniProtKB/TrEMBL),   A0A0B4J1M6 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08508-F1-model_v2 AlphaFold P08508 1-261 view protein structure

Promoters
RGD ID:6875644
Promoter ID:EPDNEW_M1273
Type:initiation region
Name:Fcgr3_1
Description:Mus musculus Fc receptor, IgG, low affinity III , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381171,059,362 - 171,059,422EPDNEW
RGD ID:6817725
Promoter ID:MM_KWN:2817
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:UC007DMY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361172,987,946 - 172,988,797 (-)MPROMDB
RGD ID:6817724
Promoter ID:MM_KWN:2818
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:NM_010188,   UC007DMX.1,   UC007DMZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361172,989,196 - 172,989,696 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95500 AgrOrtholog
Ensembl Genes ENSMUSG00000059498 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000164044 ENTREZGENE
  ENSMUST00000164044.8 UniProtKB/TrEMBL
  ENSMUST00000164179.2 UniProtKB/TrEMBL
  ENSMUST00000169017 ENTREZGENE
  ENSMUST00000169017.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95500 ENTREZGENE
NCBI Gene 14131 ENTREZGENE
PANTHER IMMUNOGLOBULIN FC RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB FCGR2A RGD
PhenoGen Fcgr3 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0B4J1M6 ENTREZGENE, UniProtKB/TrEMBL
  E9PUV2 ENTREZGENE, UniProtKB/TrEMBL
  E9PVR4_MOUSE UniProtKB/TrEMBL
  FCGR3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5D5I8_MOUSE UniProtKB/TrEMBL
  Q5D5J5_MOUSE UniProtKB/TrEMBL
  Q7TMW9_MOUSE UniProtKB/TrEMBL
  Q9ES92 ENTREZGENE, UniProtKB/TrEMBL