Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fcgr3 (Fc receptor, IgG, low affinity III) Mus musculus
Analyze
Symbol: Fcgr3
Name: Fc receptor, IgG, low affinity III
Description: Exhibits IgG binding activity and IgG receptor activity. Involved in several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including arthritis (multiple); autoimmune hypersensitivity disease (multiple); dengue disease (multiple); hematologic cancer (multiple); and leukopenia (multiple). Is expressed in liver and spleen. Orthologous to several human genes including FCGR2A (Fc fragment of IgG receptor IIa); PARTICIPATES IN Leishmaniasis pathway; Staphylococcus aureus infection pathway; systemic lupus erythematosus pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD16; Fc gamma receptor III; fc-gamma RIII; Fcg receptor III; FcgammaRIII; fcRIII; igG Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III
Orthologs:
Homo sapiens (human) : FCGR2A (Fc fragment of IgG receptor IIa)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fcgr2a (Fc fragment of IgG receptor IIa)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FCGR2A (Fc fragment of IgG receptor IIa)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1171,051,174 - 171,064,935 (-)Ensembl
GRCm381171,051,169 - 171,065,915 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,981,300 - 172,989,534 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,887,870 - 172,896,073 (-)NCBImm8
Celera1173,499,171 - 173,507,755 (-)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map178.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fcgr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736451
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.