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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcgr2a
Name: Fc gamma receptor 2A
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcgr2aincreases expressionISOFCGR2A (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of FCGR2A mRNAPMID:31059760
Fcgr2aincreases expressionISOFcgr3 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of FCGR3 mRNAPMID:31270303
Fcgr2amultiple interactionsISOFCGR2A (Homo sapiens)6480464CTD[Acetaminophen co-treated with Lipopolysaccharides] results in increased expression of FCGR2A mRNAPMID:31059760
Fcgr2amultiple interactionsISOFcgr3 (Mus musculus)6480464CTD[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of FCGR3 mRNA; Ursolic Acid inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of FCGR3 mRNA]PMID:37019307
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