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GENE - TERM ANNOTATION REPORT

RGD ID: 71069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcgr2a
Name: Fc gamma receptor 2A
Acc ID: GO:0006910
Term: phagocytosis, recognition
Definition: The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Definition Source(s): GOC:curators, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcgr2aacts_upstream_of_or_withinISOFcgr3 (Mus musculus)1624291RGDMGI:1861924 PMID:8769481 PMID:9743367 PMID:9834201

PMID:8769481 PMID:9743367 PMID:9834201
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