Ifi214 (interferon activated gene 214) - Rat Genome Database

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Gene: Ifi214 (interferon activated gene 214) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ifi214
Name: interferon activated gene 214
RGD ID: 1562462
Description: Predicted to be involved in activation of innate immune response and cellular response to interferon-beta.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289245; RGD1562462; similar to Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16); similar to Ifi204 protein
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81388,472,400 - 88,483,335 (-)NCBIGRCr8
mRatBN7.21385,940,028 - 85,951,004 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1385,940,078 - 85,951,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1388,441,494 - 88,452,428 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01389,841,778 - 89,852,709 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01387,026,510 - 87,037,441 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01391,995,940 - 92,006,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01396,511,185 - 96,521,950 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,645,912 - 89,659,179 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1385,543,036 - 85,553,962 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ifi214Ratactivation of innate immune response involved_inIEAInterPro:IPR0402051600115GO_REF:0000002InterProGO_REF:0000002
Ifi214Ratcellular response to interferon-beta involved_inIEAInterPro:IPR0402051600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15896773  



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Variants in Ifi214
105 total Variants

1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat

1 to 10 of 21 rows






Ensembl Acc Id: ENSRNOT00000103692   ⟹   ENSRNOP00000092123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1385,940,078 - 85,951,004 (-)Ensembl
RefSeq Acc Id: NM_001346366   ⟹   NP_001333295
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,472,409 - 88,483,335 (-)NCBI
mRatBN7.21385,940,078 - 85,951,004 (-)NCBI
RefSeq Acc Id: XM_039090523   ⟹   XP_038946451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81388,472,400 - 88,478,853 (-)NCBI
mRatBN7.21385,940,028 - 85,946,532 (-)NCBI
Protein RefSeqs NP_001333295 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946451 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94747 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000092123
  ENSRNOP00000092123.1
RefSeq Acc Id: XP_038946451   ⟸   XM_039090523
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AFY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001333295   ⟸   NM_001346366
- UniProtKB: A0A8I6AFY0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092123   ⟸   ENSRNOT00000103692
Pyrin


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17271 BioCyc
Ensembl Genes ENSRNOG00000065043 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000103692 ENTREZGENE
  ENSRNOT00000103692.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
InterPro DAPIN UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  HIN-200 UniProtKB/TrEMBL
KEGG Report rno:289245 UniProtKB/TrEMBL
NCBI Gene 289245 ENTREZGENE
PANTHER INTEFERON-ACTIVABLE PROTEIN 208-RELATED UniProtKB/TrEMBL
  PTHR12200 UniProtKB/TrEMBL
Pfam PYRIN UniProtKB/TrEMBL
PhenoGen Ifi214 PhenoGen
PROSITE DAPIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000065043 RatGTEx
SMART PYRIN UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
UniProt A0A8I6AFY0 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ifi214  interferon activated gene 214  RGD1562462  similar to Ifi204 protein  Symbol and Name Changed 1299863 APPROVED
2013-05-24 RGD1562462  similar to Ifi204 protein  LOC681527  similar to Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16)  Data merged from RGD:1594107 1643240 APPROVED
2013-05-24 RGD1562462  similar to Ifi204 protein  LOC689152  similar to Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16)  Data merged from RGD:1596152 1643240 APPROVED
2008-04-30 RGD1562462  similar to Ifi204 protein   RGD1562462_predicted  similar to Ifi204 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC689152  similar to Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681527  similar to Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1562462_predicted  similar to Ifi204 protein (predicted)  LOC289245  similar to Ifi204 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289245  similar to Ifi204 protein      Symbol and Name status set to provisional 70820 PROVISIONAL