Tmco1 (transmembrane and coiled-coil domains 1) - Rat Genome Database

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Gene: Tmco1 (transmembrane and coiled-coil domains 1) Rattus norvegicus
Analyze
Symbol: Tmco1
Name: transmembrane and coiled-coil domains 1
RGD ID: 1359178
Description: Predicted to enable calcium channel activity and ribosome binding activity. Predicted to be involved in several processes, including ER overload response; endoplasmic reticulum calcium ion homeostasis; and multi-pass transmembrane protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Predicted to be part of multi-pass translocon complex. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1. Orthologous to human TMCO1 (transmembrane and coiled-coil domains 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium load-activated calcium channel; CLAC channel; GEL complex subunit TMCO1; meg-2-like protein; MGC109554; putative membrane protein; transmembrane and coiled-coil domain-containing protein 1; transmembrane and coiled-coil domains protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Tmco1Tn(sb-T2/Bart3)2.135Mcwi  
Genetic Models: F344-Tmco1Tn(sb-T2/Bart3)2.135Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81381,993,172 - 82,016,496 (+)NCBIGRCr8
mRatBN7.21379,460,229 - 79,483,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,460,135 - 79,483,555 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,090,094 - 82,113,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,397,495 - 83,421,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,635,353 - 80,659,124 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,465,015 - 85,559,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,465,792 - 85,559,087 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,201,608 - 90,202,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01390,108,152 - 90,131,984 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41382,971,926 - 82,995,262 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11382,986,113 - 83,009,449 (+)NCBI
Celera1379,165,552 - 79,188,922 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
calcium channel activity  (IBA,IEA,ISO,ISS)
protein binding  (ISO)
ribosome binding  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:27212239  


Genomics

Comparative Map Data
Tmco1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81381,993,172 - 82,016,496 (+)NCBIGRCr8
mRatBN7.21379,460,229 - 79,483,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,460,135 - 79,483,555 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,090,094 - 82,113,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,397,495 - 83,421,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,635,353 - 80,659,124 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,465,015 - 85,559,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,465,792 - 85,559,087 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,201,608 - 90,202,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01390,108,152 - 90,131,984 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41382,971,926 - 82,995,262 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11382,986,113 - 83,009,449 (+)NCBI
Celera1379,165,552 - 79,188,922 (+)NCBICelera
Cytogenetic Map13q24NCBI
TMCO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,724,291 - 165,768,922 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,724,293 - 165,827,755 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,693,528 - 165,738,159 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,963,131 - 164,004,712 (-)NCBINCBI36Build 36hg18NCBI36
Celera1138,798,944 - 138,843,546 (-)NCBICelera
Cytogenetic Map1q24.1NCBI
HuRef1136,941,021 - 136,985,634 (-)NCBIHuRef
CHM1_11167,116,121 - 167,160,446 (-)NCBICHM1_1
T2T-CHM13v2.01165,070,667 - 165,115,003 (-)NCBIT2T-CHM13v2.0
Tmco1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,136,239 - 167,161,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,135,947 - 167,161,547 (+)EnsemblGRCm39 Ensembl
GRCm381167,308,670 - 167,333,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,308,378 - 167,333,978 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,238,801 - 169,264,109 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,145,345 - 169,170,653 (+)NCBIMGSCv36mm8
Celera1169,726,087 - 169,751,228 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.69NCBI
Tmco1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546210,925,383 - 10,973,814 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546210,925,383 - 10,973,814 (+)NCBIChiLan1.0ChiLan1.0
TMCO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,996,652 - 84,038,263 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,662,962 - 83,706,945 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01141,159,657 - 141,201,018 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,948,169 - 144,989,880 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,944,105 - 144,989,794 (-)Ensemblpanpan1.1panPan2
TMCO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,579,540 - 17,630,701 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,579,607 - 17,630,283 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,636,060 - 17,687,125 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,634,996 - 17,686,216 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,635,061 - 17,687,020 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,633,018 - 17,684,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03817,983,898 - 18,035,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,278,071 - 18,329,208 (+)NCBIUU_Cfam_GSD_1.0
Tmco1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,740,129 - 101,762,289 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,586,870 - 19,611,933 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,586,870 - 19,609,043 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMCO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl484,961,819 - 85,017,820 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1484,961,912 - 85,011,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,618,554 - 92,667,781 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMCO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,110,626 - 63,150,602 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,110,772 - 63,150,017 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605564,870,612 - 64,911,995 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmco1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248264,064,126 - 4,118,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmco1
84 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:67
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000005277
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)137402391880753406Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat

Markers in Region
RH133298  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21379,483,096 - 79,483,291 (+)MAPPERmRatBN7.2
Rnor_6.01385,488,760 - 85,488,954NCBIRnor6.0
Rnor_6.01385,558,653 - 85,558,847NCBIRnor6.0
Rnor_5.01390,201,786 - 90,201,980UniSTSRnor5.0
Rnor_5.01390,131,893 - 90,132,087UniSTSRnor5.0
RGSC_v3.41382,994,802 - 82,994,996UniSTSRGSC3.4
Celera1379,188,462 - 79,188,656UniSTS
RH 3.4 Map13522.8UniSTS
Cytogenetic Map13q23UniSTS
AA109065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21379,460,285 - 79,460,848 (+)MAPPERmRatBN7.2
Rnor_6.01385,465,941 - 85,466,503NCBIRnor6.0
Rnor_5.01390,109,074 - 90,109,636UniSTSRnor5.0
RGSC_v3.41382,971,983 - 82,972,545UniSTSRGSC3.4
Celera1379,165,609 - 79,166,171UniSTS
Cytogenetic Map13q23UniSTS


Genetic Models
This gene Tmco1 is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000005277   ⟹   ENSRNOP00000005277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,460,135 - 79,477,544 (+)Ensembl
Rnor_6.0 Ensembl1385,465,933 - 85,488,680 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082991   ⟹   ENSRNOP00000074404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,466,088 - 79,483,555 (+)Ensembl
Rnor_6.0 Ensembl1385,465,792 - 85,559,087 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094502   ⟹   ENSRNOP00000078430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,460,135 - 79,476,742 (+)Ensembl
RefSeq Acc Id: NM_001009631   ⟹   NP_001009631
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81381,993,172 - 82,016,496 (+)NCBI
mRatBN7.21379,460,229 - 79,483,557 (+)NCBI
Rnor_6.01385,465,884 - 85,559,113 (+)NCBI
Rnor_5.01390,201,608 - 90,202,246 (+)NCBI
RGSC_v3.41382,971,926 - 82,995,262 (+)RGD
Celera1379,165,552 - 79,188,922 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009631 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88319 (Get FASTA)   NCBI Sequence Viewer  
  AAQ09812 (Get FASTA)   NCBI Sequence Viewer  
  EDM09284 (Get FASTA)   NCBI Sequence Viewer  
  EDM09285 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005277.5
  ENSRNOP00000074404.2
  ENSRNOP00000078430.1
GenBank Protein Q5I0H4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009631   ⟸   NM_001009631
- UniProtKB: Q71DI0 (UniProtKB/Swiss-Prot),   Q5I0H4 (UniProtKB/Swiss-Prot),   A6IDL2 (UniProtKB/TrEMBL),   A0A8L2Q2R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074404   ⟸   ENSRNOT00000082991
RefSeq Acc Id: ENSRNOP00000005277   ⟸   ENSRNOT00000005277
RefSeq Acc Id: ENSRNOP00000078430   ⟸   ENSRNOT00000094502

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5I0H4-F1-model_v2 AlphaFold Q5I0H4 1-188 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698972
Promoter ID:EPDNEW_R9497
Type:initiation region
Name:Tmco1_1
Description:transmembrane and coiled-coil domains 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01385,465,804 - 85,465,864EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359178 AgrOrtholog
BioCyc Gene G2FUF-17523 BioCyc
Ensembl Genes ENSRNOG00000003928 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005277.7 UniProtKB/TrEMBL
  ENSRNOT00000082991.2 UniProtKB/TrEMBL
  ENSRNOT00000094502.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7325542 IMAGE-MGC_LOAD
InterPro EMC3/TMCO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TMCO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:289196 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109554 IMAGE-MGC_LOAD
NCBI Gene 289196 ENTREZGENE
PANTHER CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR20917 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EMC3_TMCO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmco1 PhenoGen
PIRSF DUF841_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003928 RatGTEx
SMART DUF106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZKU0_RAT UniProtKB/TrEMBL
  A0A8L2Q2R5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R8R9_RAT UniProtKB/TrEMBL
  A6IDL2 ENTREZGENE, UniProtKB/TrEMBL
  A6IDL3_RAT UniProtKB/TrEMBL
  Q5I0H4 ENTREZGENE
  Q71DI0 ENTREZGENE
  TMCO1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q71DI0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Tmco1  transmembrane and coiled-coil domains 1  MGC109554  putative membrane protein  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC109554  putative membrane protein      Symbol and Name status set to provisional 70820 PROVISIONAL