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Gene: Soat1 (sterol O-acyltransferase 1) Rattus norvegicus
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Symbol: Soat1
Name: sterol O-acyltransferase 1
Description: Exhibits sterol O-acyltransferase activity. Predicted to be involved in several processes, including cholesterol efflux; cholesterol esterification; and macrophage derived foam cell differentiation. Predicted to localize to the endoplasmic reticulum membrane. Orthologous to human SOAT1 (sterol O-acyltransferase 1); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acat-1; acyl coenzyme A:cholesterol acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase 1; cholesterol acyltransferase 1
Orthologs:
Homo sapiens (human) : SOAT1 (sterol O-acyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Soat1 (sterol O-acyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Soat1 (sterol O-acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SOAT1 (sterol O-acyltransferase 1)
Canis lupus familiaris (dog) : SOAT1 (sterol O-acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Soat1 (sterol O-acyltransferase 1)
Sus scrofa (pig) : SOAT1 (sterol O-acyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01374,035,258 - 74,077,759 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01378,956,528 - 78,999,029 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,420,862 - 71,463,365 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11371,435,049 - 71,477,553 (-)NCBI
Celera1368,416,482 - 68,458,206 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Soat1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621641
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.