Gene: Cd247 (Cd247 molecule) Rattus norvegicus
Symbol: Cd247
Name: Cd247 molecule
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); protein tyrosine kinase binding (ortholog); INVOLVED IN cell surface receptor signaling pathway; protein homotetramerization (ortholog); protein homotrimerization (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; T cell receptor signaling pathway; Trypanosoma cruzi infection pathway; ASSOCIATED WITH decreased B cell number; decreased monocyte cell number; decreased splenocyte proliferation; ASSOCIATED WITH Immunodeficiency due to Defect in CD3-Zeta (ortholog); Scleroderma, Systemic (ortholog); Severe Combined Immunodeficiency (ortholog); FOUND IN T cell receptor complex; alpha-beta T cell receptor complex (ortholog); cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD247 antigen; CD3 antigen, zeta polypeptide; Cd3z; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell surface glycoprotein CD3 zeta chain; TCRzeta
Homo sapiens (human) : CD247 (CD247 molecule)  HGNC  AGR
Mus musculus (house mouse) : Cd247 (CD247 antigen)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Cd247 (CD247 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD247 (CD247 molecule)
Canis lupus familiaris (dog) : CD247 (CD247 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd247 (CD247 molecule)
more info ...
Allele / Splice: Cd247em1Mcwi   Cd247em5Mcwi   Cd247em3Mcwi  
Genetic Models: SS-Cd247em3Mcwi SS-Cd247em1Mcwi SS-Cd247em5Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01383,996,045 - 84,071,408 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01388,876,046 - 88,951,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41381,515,383 - 81,594,699 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11381,529,570 - 81,608,887 (+)NCBI
Celera1377,754,426 - 77,829,099 (+)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cd247
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2305
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE