Nit1 (nitrilase 1) - Rat Genome Database

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Gene: Nit1 (nitrilase 1) Rattus norvegicus
Analyze
Symbol: Nit1
Name: nitrilase 1
RGD ID: 727821
Description: Predicted to enable deaminated glutathione amidase activity. Predicted to be involved in cellular amide catabolic process. Predicted to be located in mitochondrion. Orthologous to human NIT1 (nitrilase 1); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: deaminated glutathione amidase; dGSH amidase; MGC95151; nitrilase homolog 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,769,888 - 83,773,324 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,765,941 - 83,773,332 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,275,650 - 86,279,086 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01387,673,861 - 87,677,297 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01384,909,943 - 84,913,387 (-)NCBIRnor_WKY
Rnor_6.01389,722,370 - 89,725,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,722,374 - 89,725,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,349,703 - 94,353,139 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,242,619 - 87,246,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,431,510 - 87,434,235 (-)NCBI
Celera1383,400,571 - 83,404,007 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
antimycin A  (ISO)
aristolochic acid  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium dichloride  (EXP)
CGP 52608  (ISO)
chloroprene  (EXP)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
decabromodiphenyl ether  (ISO)
diazinon  (EXP,ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
iodide salt  (EXP)
ivermectin  (ISO)
L-ethionine  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nefazodone  (EXP)
Nonylphenol  (EXP)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
rotenone  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
mitochondrion  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
3. The nitrilase superfamily: classification, structure and function. Pace HC and Brenner C, Genome Biol 2001;2(1):REVIEWS0001. Epub 2001 Jan 15.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16864578   PMID:18614015   PMID:19053248   PMID:21630459   PMID:21873635   PMID:23376485   PMID:28373563  


Genomics

Comparative Map Data
Nit1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21383,769,888 - 83,773,324 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,765,941 - 83,773,332 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,275,650 - 86,279,086 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01387,673,861 - 87,677,297 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01384,909,943 - 84,913,387 (-)NCBIRnor_WKY
Rnor_6.01389,722,370 - 89,725,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,722,374 - 89,725,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,349,703 - 94,353,139 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,242,619 - 87,246,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,431,510 - 87,434,235 (-)NCBI
Celera1383,400,571 - 83,404,007 (-)NCBICelera
Cytogenetic Map13q24NCBI
NIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,118,105 - 161,125,445 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1161,118,086 - 161,125,445 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,087,895 - 161,095,235 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,354,515 - 159,357,481 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,900,963 - 157,903,930NCBI
Celera1134,155,024 - 134,162,397 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,445,260 - 132,452,414 (+)NCBIHuRef
CHM1_11162,484,103 - 162,491,482 (+)NCBICHM1_1
T2T-CHM13v2.01160,255,574 - 160,262,920 (+)NCBIT2T-CHM13v2.0
Nit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,168,139 - 171,173,224 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,165,576 - 171,173,214 (-)EnsemblGRCm39 Ensembl
GRCm381171,340,571 - 171,345,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,338,008 - 171,345,646 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,272,368 - 173,275,776 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,178,919 - 173,182,301 (-)NCBIMGSCv36mm8
Celera1173,793,725 - 173,797,135 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.35NCBI
Nit1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,882,765 - 12,888,479 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,882,765 - 12,885,642 (+)NCBIChiLan1.0ChiLan1.0
NIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11140,443,751 - 140,446,874 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,443,763 - 140,449,831 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01136,530,490 - 136,533,619 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,352,236 - 21,355,636 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,348,486 - 21,356,260 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,426,271 - 21,429,701 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,469,764 - 21,473,194 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,466,017 - 21,473,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,357,920 - 21,361,348 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,771,943 - 21,775,377 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,181,173 - 22,184,607 (-)NCBIUU_Cfam_GSD_1.0
Nit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,223,645 - 7,228,035 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936903432,585 - 436,697 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NIT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,320,712 - 89,327,066 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,323,598 - 89,327,057 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,180,537 - 97,183,754 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,859,582 - 2,862,688 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,860,008 - 2,862,601 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,906,929 - 1,910,035 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nit1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794254,766 - 257,759 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794254,766 - 258,046 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
AF069985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,769,929 - 83,770,043 (+)MAPPERmRatBN7.2
Rnor_6.01389,722,412 - 89,722,525NCBIRnor6.0
Rnor_5.01394,349,745 - 94,349,858UniSTSRnor5.0
RGSC_v3.41387,242,661 - 87,242,774UniSTSRGSC3.4
Celera1383,400,613 - 83,400,726UniSTS
Cytogenetic Map13q24UniSTS
BF387362  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,772,326 - 83,772,511 (+)MAPPERmRatBN7.2
Rnor_6.01389,724,809 - 89,724,993NCBIRnor6.0
Rnor_5.01394,352,142 - 94,352,326UniSTSRnor5.0
RGSC_v3.41387,245,058 - 87,245,242UniSTSRGSC3.4
Celera1383,403,010 - 83,403,194UniSTS
RH 3.4 Map13554.6UniSTS
Cytogenetic Map13q24UniSTS
RH134594  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,769,737 - 83,769,952 (+)MAPPERmRatBN7.2
Rnor_6.01389,722,220 - 89,722,434NCBIRnor6.0
Rnor_5.01394,349,553 - 94,349,767UniSTSRnor5.0
RGSC_v3.41387,242,469 - 87,242,683UniSTSRGSC3.4
Celera1383,400,421 - 83,400,635UniSTS
RH 3.4 Map13554.9UniSTS
Cytogenetic Map13q24UniSTS
AA818913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,770,038 - 83,770,134 (+)MAPPERmRatBN7.2
Rnor_6.01389,722,521 - 89,722,616NCBIRnor6.0
Rnor_5.01394,349,854 - 94,349,949UniSTSRnor5.0
RGSC_v3.41387,242,770 - 87,242,865UniSTSRGSC3.4
Celera1383,400,722 - 83,400,817UniSTS
RH 3.4 Map13550.2UniSTS
Cytogenetic Map13q24UniSTS
AA945617  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,770,017 - 83,770,166 (+)MAPPERmRatBN7.2
Rnor_6.01389,722,500 - 89,722,648NCBIRnor6.0
Rnor_5.01394,349,833 - 94,349,981UniSTSRnor5.0
RGSC_v3.41387,242,749 - 87,242,897UniSTSRGSC3.4
Celera1383,400,701 - 83,400,849UniSTS
RH 3.4 Map13562.2UniSTS
Cytogenetic Map13q24UniSTS
W57327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,772,072 - 83,772,649 (+)MAPPERmRatBN7.2
Rnor_6.01389,724,555 - 89,725,131NCBIRnor6.0
Rnor_5.01394,351,888 - 94,352,464UniSTSRnor5.0
RGSC_v3.41387,244,804 - 87,245,380UniSTSRGSC3.4
Celera1383,402,756 - 83,403,332UniSTS
Cytogenetic Map13q24UniSTS
PMC21147P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,772,584 - 83,772,678 (+)MAPPERmRatBN7.2
Rnor_6.01389,725,067 - 89,725,160NCBIRnor6.0
Rnor_5.01394,352,400 - 94,352,493UniSTSRnor5.0
RGSC_v3.41387,245,316 - 87,245,409UniSTSRGSC3.4
Celera1383,403,268 - 83,403,361UniSTS
Cytogenetic Map13q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:34
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000005194
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001082580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001305646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001305647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY300752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB576182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO558072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV073582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM045849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000005194   ⟹   ENSRNOP00000005194
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,769,891 - 83,772,749 (-)Ensembl
Rnor_6.0 Ensembl1389,722,374 - 89,725,806 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111317   ⟹   ENSRNOP00000087783
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,765,941 - 83,773,325 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117822   ⟹   ENSRNOP00000096370
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,769,892 - 83,773,332 (-)Ensembl
RefSeq Acc Id: NM_001082580   ⟹   NP_001076049
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,773,324 (-)NCBI
Rnor_6.01389,722,370 - 89,725,806 (-)NCBI
Rnor_5.01394,349,703 - 94,353,139 (-)NCBI
RGSC_v3.41387,242,619 - 87,246,055 (-)RGD
Celera1383,400,571 - 83,404,007 (-)RGD
Sequence:
RefSeq Acc Id: NM_001305646   ⟹   NP_001292575
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,773,324 (-)NCBI
Rnor_6.01389,722,370 - 89,725,806 (-)NCBI
Celera1383,400,571 - 83,404,007 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001305647   ⟹   NP_001292576
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,772,345 (-)NCBI
Rnor_6.01389,722,370 - 89,724,827 (-)NCBI
Celera1383,400,571 - 83,403,028 (-)NCBI
Sequence:
RefSeq Acc Id: NM_182668   ⟹   NP_872609
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,773,324 (-)NCBI
Rnor_6.01389,722,370 - 89,725,806 (-)NCBI
Rnor_5.01394,349,703 - 94,353,139 (-)NCBI
RGSC_v3.41387,242,619 - 87,246,055 (-)RGD
Celera1383,400,571 - 83,404,007 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090510   ⟹   XP_038946438
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,773,319 (-)NCBI
RefSeq Acc Id: XM_039090511   ⟹   XP_038946439
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21383,769,888 - 83,772,191 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_872609   ⟸   NM_182668
- Peptide Label: isoform a
- UniProtKB: Q5PQK6 (UniProtKB/Swiss-Prot),   Q7TQ94 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001076049   ⟸   NM_001082580
- Peptide Label: isoform b
- UniProtKB: Q7TQ94 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001292575   ⟸   NM_001305646
- Peptide Label: isoform c
- UniProtKB: Q7TQ94 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001292576   ⟸   NM_001305647
- Peptide Label: isoform b
- UniProtKB: Q7TQ94 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005194   ⟸   ENSRNOT00000005194
RefSeq Acc Id: XP_038946438   ⟸   XM_039090510
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946439   ⟸   XM_039090511
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000096370   ⟸   ENSRNOT00000117822
RefSeq Acc Id: ENSRNOP00000087783   ⟸   ENSRNOT00000111317
Protein Domains
CN hydrolase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TQ94-F1-model_v2 AlphaFold Q7TQ94 1-327 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699005
Promoter ID:EPDNEW_R9529
Type:initiation region
Name:Nit1_1
Description:nitrilase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,725,803 - 89,725,863EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 89722879 89722880 C T snv CDR, WKY/N (2020), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH3/CubMcwi (2020), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), CDS
13 89722884 89722885 A G snv CDR, WKY/N (2020), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH3/CubMcwi (2020), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), CDS
13 89722896 89722897 T C snv CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH3/CubMcwi (2020), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020)
13 89722912 89722913 G C snv CDR, WKY/N (2020), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/SsN (2020), BUF/N (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), CDS
13 89722914 89722915 G A snv SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW)
13 89722918 89722919 G A snv DA/OlaHsd (2019), BXH3/CubMcwi (2020), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), F344/DuCrl (2019)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 94350212 94350213 C T snv SDLEF7/Barth (UDEL), ZF (KyushuU), Crl:SD (UDEL), IS/Kyo (KyushuU), BUF/MNa (KyushuU), F344/DuCrlCrlj (KyushuU), LE/Stm (KyushuU), HTX/Kyo (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), F344/Jcl (KyushuU), BDIX/NemOda (KyushuU), DOB/Oda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), KFRS3B/Kyo (KyushuU), LE/OrlBarth (UDEL)
13 94350217 94350218 A G snv SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), IS/Kyo (KyushuU), BUF/MNa (KyushuU), F344/DuCrlCrlj (KyushuU), LE/Stm (KyushuU), HTX/Kyo (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), F344/Jcl (KyushuU), BDIX/NemOda (KyushuU), DOB/Oda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), KFRS3B/Kyo (KyushuU), ZF (KyushuU)
13 94350229 94350230 T C snv ZFDM (KyushuU), SDLEF7/Barth (UDEL), KFRS3B/Kyo (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), DOB/Oda (KyushuU), BDIX/NemOda (KyushuU), F344/Jcl (KyushuU), IS-Tlk/Kyo (KyushuU), RCS/Kyo (KyushuU), HTX/Kyo (KyushuU), LE/Stm (KyushuU), F344/DuCrlCrlj (KyushuU), BUF/MNa (KyushuU), IS/Kyo (KyushuU), Crl:SD (UDEL), LE/OrlBarth (UDEL), ZF (KyushuU)
13 94350245 94350246 G C snv ZF (KyushuU), ZFDM (KyushuU), KFRS3B/Kyo (KyushuU), DOB/Oda (KyushuU), LEC/Tj (KyushuU), IS-Tlk/Kyo (KyushuU), HTX/Kyo (KyushuU), F344/DuCrlCrlj (KyushuU), BUF/MNa (KyushuU), IS/Kyo (KyushuU), Crl:SD (UDEL), LE/OrlBarth (UDEL), SDLEF7/Barth (UDEL)
13 94350247 94350248 G A snv LE/OrlBarth (UDEL), Crl:SD (UDEL), IS/Kyo (KyushuU), BUF/MNa (KyushuU), F344/DuCrlCrlj (KyushuU), HTX/Kyo (KyushuU), SDLEF7/Barth (UDEL), IS-Tlk/Kyo (KyushuU), DOB/Oda (KyushuU), KFRS3B/Kyo (KyushuU), ZF (KyushuU), ZFDM (KyushuU), RCS/Kyo (KyushuU)
13 94350251 94350252 G A snv NIG-III/Hok (KyushuU), F344/DuCrlCrlj (KyushuU), HTX/Kyo (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), LEC/Tj (KyushuU), DOB/Oda (KyushuU), KFRS3B/Kyo (KyushuU), ZF (KyushuU), ZFDM (KyushuU), IS/Kyo (KyushuU), Crl:SD (UDEL), BUF/MNa (KyushuU), LE/OrlBarth (UDEL), SDLEF7/Barth (UDEL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727821 AgrOrtholog
BioCyc Gene G2FUF-17373 BioCyc
Ensembl Genes ENSRNOG00000003881 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005194 ENTREZGENE
  ENSRNOP00000005194.6 UniProtKB/TrEMBL
  ENSRNOP00000087783.1 UniProtKB/TrEMBL
  ENSRNOP00000096370 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005194 ENTREZGENE
  ENSRNOT00000005194.6 UniProtKB/TrEMBL
  ENSRNOT00000111317.1 UniProtKB/TrEMBL
  ENSRNOT00000117822 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7129801 IMAGE-MGC_LOAD
InterPro C-N_Hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-N_Hydrolase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nit1/2_C-N_Hydrolase UniProtKB/Swiss-Prot
  UPF0012_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:289222 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95151 IMAGE-MGC_LOAD
NCBI Gene 289222 ENTREZGENE
Pfam CN_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nit1 PhenoGen
PROSITE CN_HYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UPF0012 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AHC1_RAT UniProtKB/TrEMBL
  A0A8L2Q1A7_RAT UniProtKB/TrEMBL
  NIT1_RAT UniProtKB/Swiss-Prot
  Q5PQK6 ENTREZGENE
  Q7TQ94 ENTREZGENE
UniProt Secondary Q5PQK6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Nit1  nitrilase 1      Symbol and Name status set to approved 1299863 APPROVED