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Gene: Selp (selectin P) Rattus norvegicus
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Symbol: Selp
Name: selectin P
Description: Predicted to have several functions, including anion binding activity; fucose binding activity; and lipopolysaccharide binding activity. Involved in several processes, including leukocyte migration; regulation of cellular extravasation; and response to lipopolysaccharide. Localizes to the external side of plasma membrane and extracellular space. Used to study anti-basement membrane glomerulonephritis. Biomarker of atherosclerosis; colitis; congestive heart failure; and myocardial infarction. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (selectin P); PARTICIPATES IN interleukin-4 signaling pathway; malaria pathway; Staphylococcus aureus infection pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4-(ethoxymethylene)-2-phenyloxazol-5-one.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD62 antigen-like family member P; GMP-140; granule membrane protein 140; LECAM3; leukocyte-endothelial cell adhesion molecule 3; MGC124632; P-selectin; PADGEM; platelet activation dependent granule-external membrane protein; PSELECT; Selectin platelet; selectin, platelet
Orthologs:
Homo sapiens (human) : SELP (selectin P)  HGNC  Alliance
Mus musculus (house mouse) : Selp (selectin, platelet)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Selp (selectin P)
Pan paniscus (bonobo/pygmy chimpanzee) : SELP (selectin P)
Canis lupus familiaris (dog) : SELP (selectin P)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Selp (selectin P)
Sus scrofa (pig) : SELP (selectin P)
more info ...
Is Marker For: Strains:   F344.ACI-Lmx1aqc/Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01382,428,914 - 82,464,629 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,429,063 - 82,464,628 (+)Ensembl
Rnor_5.01387,308,435 - 87,344,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,886,614 - 79,922,180 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11379,910,278 - 79,936,368 (+)NCBI
Celera1376,209,805 - 76,244,685 (+)NCBICelera
Cytogenetic Map13q23NCBI
RH 3.4 Map13482.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Selp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3656
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.