Tor1aip2 (torsin 1A interacting protein 2) - Rat Genome Database
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Gene: Tor1aip2 (torsin 1A interacting protein 2) Rattus norvegicus
Analyze
Symbol: Tor1aip2
Name: torsin 1A interacting protein 2
RGD ID: 735059
Description: Predicted to have ATPase activator activity and ATPase binding activity. Predicted to be involved in endoplasmic reticulum organization; positive regulation of ATPase activity; and protein localization to nuclear envelope. Predicted to localize to endoplasmic reticulum. Orthologous to human TOR1AIP2 (torsin 1A interacting protein 2); INTERACTS WITH bisphenol A; cobalt dichloride; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: interferon alpha responsive; MGC72610; torsin A interacting protein 2; torsin-1A-interacting protein 2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21368,225,226 - 68,256,536 (+)NCBI
Rnor_6.0 Ensembl1373,708,815 - 73,720,429 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1373,708,815 - 73,735,339 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01373,704,088 - 73,735,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01378,629,216 - 78,660,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,076,913 - 71,103,437 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11371,091,143 - 71,115,159 (+)NCBI
Celera1368,092,630 - 68,119,154 (+)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15489334   PMID:15767459   PMID:19339278   PMID:23569223   PMID:24275647   PMID:25002582  


Genomics

Comparative Map Data
Tor1aip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21368,225,226 - 68,256,536 (+)NCBI
Rnor_6.0 Ensembl1373,708,815 - 73,720,429 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1373,708,815 - 73,735,339 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01373,704,088 - 73,735,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01378,629,216 - 78,660,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,076,913 - 71,103,437 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11371,091,143 - 71,115,159 (+)NCBI
Celera1368,092,630 - 68,119,154 (+)NCBICelera
Cytogenetic Map13q22NCBI
TOR1AIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1179,839,967 - 179,877,803 (-)EnsemblGRCh38hg38GRCh38
GRCh381179,839,976 - 179,877,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371179,809,111 - 179,846,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361178,080,576 - 178,113,557 (-)NCBINCBI36hg18NCBI36
Celera1152,920,678 - 152,954,553 (-)NCBI
Cytogenetic Map1q25.2NCBI
HuRef1151,040,947 - 151,078,786 (-)NCBIHuRef
CHM1_11181,232,909 - 181,270,748 (-)NCBICHM1_1
Tor1aip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,911,410 - 155,944,607 (+)NCBIGRCm39mm39
GRCm39 Ensembl1155,911,149 - 155,944,607 (+)Ensembl
GRCm381156,035,664 - 156,068,861 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,035,403 - 156,068,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv371157,882,794 - 157,915,991 (+)NCBIGRCm37mm9NCBIm37
MGSCv361157,813,801 - 157,831,079 (+)NCBImm8
Celera1158,473,578 - 158,506,940 (+)NCBICelera
Cytogenetic Map1G3NCBI
TOR1AIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11159,005,944 - 159,039,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,005,944 - 159,039,058 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01155,321,181 - 155,358,966 (-)NCBIMhudiblu_PPA_v0panPan3
LOC106557472
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl713,414,910 - 13,435,161 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1713,411,955 - 13,453,366 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC106144612
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364819,266,527 - 9,280,289 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOR1AIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9121,476,500 - 121,516,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19121,476,501 - 121,516,611 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103230506
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12549,496,515 - 49,532,881 (+)NCBI
ChlSab1.1 Ensembl2549,509,484 - 49,530,723 (+)Ensembl

Position Markers
RH131284  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01373,721,058 - 73,721,258NCBIRnor6.0
Rnor_5.01378,646,107 - 78,646,307UniSTSRnor5.0
RGSC_v3.41371,089,156 - 71,089,356UniSTSRGSC3.4
Celera1368,104,873 - 68,105,073UniSTS
Cytogenetic Map13q21UniSTS
RH134550  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01373,719,449 - 73,719,643NCBIRnor6.0
Rnor_5.01378,644,498 - 78,644,692UniSTSRnor5.0
RGSC_v3.41371,087,547 - 71,087,741UniSTSRGSC3.4
Celera1368,103,264 - 68,103,458UniSTS
Cytogenetic Map13q21UniSTS
RH139660  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01373,734,906 - 73,735,108NCBIRnor6.0
Rnor_5.01378,659,955 - 78,660,157UniSTSRnor5.0
RGSC_v3.41371,103,004 - 71,103,206UniSTSRGSC3.4
Celera1368,118,721 - 68,118,923UniSTS
RH 3.4 Map13355.6UniSTS
Cytogenetic Map13q21UniSTS
AA892455  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01373,732,561 - 73,732,740NCBIRnor6.0
Rnor_5.01378,657,610 - 78,657,789UniSTSRnor5.0
RGSC_v3.41371,100,659 - 71,100,838UniSTSRGSC3.4
Celera1368,116,376 - 68,116,555UniSTS
RH 3.4 Map13355.7UniSTS
Cytogenetic Map13q21UniSTS
AA892455  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01373,732,469 - 73,732,579NCBIRnor6.0
Rnor_5.01378,657,518 - 78,657,628UniSTSRnor5.0
RGSC_v3.41371,100,567 - 71,100,677UniSTSRGSC3.4
Celera1368,116,284 - 68,116,394UniSTS
RH 3.4 Map13355.7UniSTS
Cytogenetic Map13q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135156924896569248Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1372583716114033958Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1362975663107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1357903612102903612Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)135157782490675199Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)136450135182995671Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136361128379034003Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1371230858114033958Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1371230858114033958Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1366971778111971778Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135108098996080989Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136500824591629354Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1686
Count of miRNA genes:375
Interacting mature miRNAs:547
Transcripts:ENSRNOT00000050734, ENSRNOT00000071482
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 65 113 81 38 81 16 20 95 69 81 22 16
Low 21 2 53
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001165896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_199100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC061831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB804669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK478392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO565924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV107022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV728294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV767100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000050734   ⟹   ENSRNOP00000039176
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1373,708,815 - 73,735,339 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000071482   ⟹   ENSRNOP00000064775
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1373,708,815 - 73,720,429 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077874   ⟹   ENSRNOP00000071656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1373,708,815 - 73,720,429 (+)Ensembl
RefSeq Acc Id: NM_001165896   ⟹   NP_001159368
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,230,009 - 68,241,623 (+)NCBI
Rnor_6.01373,708,815 - 73,720,429 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
RGSC_v3.41371,076,913 - 71,103,437 (+)RGD
Celera1368,092,630 - 68,104,244 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165897   ⟹   NP_001159369
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,230,009 - 68,241,623 (+)NCBI
Rnor_6.01373,708,815 - 73,720,429 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
RGSC_v3.41371,076,913 - 71,103,437 (+)RGD
Celera1368,092,630 - 68,104,244 (+)NCBI
Sequence:
RefSeq Acc Id: NM_199100   ⟹   NP_954531
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,230,009 - 68,256,536 (+)NCBI
Rnor_6.01373,708,815 - 73,735,339 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
RGSC_v3.41371,076,913 - 71,103,437 (+)RGD
Celera1368,092,630 - 68,119,154 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250043   ⟹   XP_006250105
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,239,630 - 68,256,532 (+)NCBI
Rnor_6.01373,718,486 - 73,735,335 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250044   ⟹   XP_006250106
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01373,708,986 - 73,735,335 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250045   ⟹   XP_006250107
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,225,233 - 68,256,532 (+)NCBI
Rnor_6.01373,704,088 - 73,735,338 (+)NCBI
Rnor_5.01378,629,216 - 78,660,388 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090735   ⟹   XP_038946663
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,230,027 - 68,256,532 (+)NCBI
RefSeq Acc Id: XM_039090736   ⟹   XP_038946664
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,225,226 - 68,256,532 (+)NCBI
RefSeq Acc Id: XM_039090737   ⟹   XP_038946665
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21368,229,966 - 68,256,532 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_954531   ⟸   NM_199100
- Peptide Label: isoform b
- UniProtKB: Q6P752 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159368   ⟸   NM_001165896
- Peptide Label: isoform a
- UniProtKB: M0R5U6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159369   ⟸   NM_001165897
- Peptide Label: isoform a
- UniProtKB: M0R5U6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250107   ⟸   XM_006250045
- Peptide Label: isoform X1
- UniProtKB: Q6P752 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250106   ⟸   XM_006250044
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006250105   ⟸   XM_006250043
- Peptide Label: isoform X1
- UniProtKB: Q6P752 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071656   ⟸   ENSRNOT00000077874
RefSeq Acc Id: ENSRNOP00000064775   ⟸   ENSRNOT00000071482
RefSeq Acc Id: ENSRNOP00000039176   ⟸   ENSRNOT00000050734
RefSeq Acc Id: XP_038946664   ⟸   XM_039090736
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946665   ⟸   XM_039090737
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946663   ⟸   XM_039090735
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698913
Promoter ID:EPDNEW_R9438
Type:initiation region
Name:Tor1aip2_1
Description:torsin 1A interacting protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01373,708,827 - 73,708,887EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 78653419 78653420 G A snv SBN/Ygl (MCW), IS-Tlk/Kyo (KyushuU), IS/Kyo (KyushuU), SBN/Ygl (KNAW)
13 78653452 78653453 A G snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/EurMcwi (KNAW), ACI/N (KNAW)
13 78653693 78653694 A G snv WKY/N (KNAW), DA/BklArbNsi (KNAW), LE/Stm (SOLiD) (KNAW), IS/Kyo (KyushuU), KFRS3B/Kyo (KyushuU), SR/JrHsd (KNAW), F344/NHsd (KNAW), FHL/EurMcwi (KNAW), LE/Stm (Illumina) (KNAW), F344/DuCrlCrlj (KyushuU), LEC/Tj (KyushuU), SR/JrHsd (MCW), LN/MavRrrc (KNAW), LE/OrlBarth (UDEL), F344/NSlc (KyushuU), SS/Jr (KNAW), ACI/N (KNAW), SHR/OlaIpcvPrin (KNAW), F344/Stm (KyushuU), WKY/NCrl (KNAW), WKY/NHsd (KNAW), M520/N (KNAW), Crl:SD (UDEL), IS-Tlk/Kyo (KyushuU), COP/CrCrl (MCW & UW), LH/MavRrrc (KNAW), BUF/N (KNAW), HWY/Slc (KyushuU), FHL/EurMcwi (MCW), SBN/Ygl (MCW), SBN/Ygl (KNAW), SHR/NHsd (KNAW), SHR/OlaIpcv (KNAW), SHRSP/Gcrc (KNAW), BUF/MNa (KyushuU), NIG-III/Hok (KyushuU), LE/Stm (KyushuU), F344/Jcl (KyushuU), BDIX/NemOda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), ACI/EurMcwi (MCW), SHR/NCrlPrin (KNAW), WKY/Gcrc (KNAW), WN/N (KNAW), SDLEF7/Barth (UDEL), ACI/EurMcwi (KNAW), MHS/Gib (KNAW), F344/NCrl (KNAW), F344/NRrrc (SOLiD) (KNAW), SS/JrHsdMcwi (KNAW), LL/MavRrrc (KNAW), SS/JrHsdMcwi (MCW), GH/OmrMcwi (MCW), F344/NRrrc (Illumina) (KNAW), RCS/Kyo (KyushuU)
13 78656530 78656531 T G snv SR/JrHsd (MCW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 73718833 73718834 G A snv Buf/N (MCW)
13 73728370 73728371 G A snv CDR, SBN/Ygl (RGD), SBN/Ygl (MCW)
13 73728403 73728404 A G snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/EurMcwi (RGD), ACI/N (MCW)
13 73728644 73728645 A G snv SS/Jr (RGD), WKY/Gcrc (RGD), ACI/N (MCW), Buf/N (MCW), LL/MavRrrc (RGD), SBN/Ygl (RGD), SHR/NHsd (RGD), SS/JrHsdMcwi (MCW), LE/Stm (RGD), LN/MavRrrc (RGD), FHL/EurMcwi (MCW), F344/NRrrc (MCW), SS/JrHsdMcwi (RGD), F344/NCrl (RGD), MHS/Gib (RGD), WKY/NCrl (RGD), CDR, WN/N (MCW), SR/JrHsd (RGD), LH/MavRrrc (RGD), ACI/EurMcwi (RGD), SR/JrHsd (MCW), SBN/Ygl (MCW), GH/OmrMcwi (MCW), COP/CrCrl (MCW & UW), WKY/NHsd (RGD), ACI/EurMcwi (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 71086931 71086932 G A snv LCR/2Mco (UMich), BUF/N (KNAW)
13 71096468 71096469 G A snv SBN/Ygl (ICL)
13 71096501 71096502 A G snv COP/CrCrl (MCW & UW), ACI/N (KNAW), LCR/1Mco (UMich), HCR/1Mco (UMich), LCR/2Mco (UMich), HCR/2Mco (UMich), ACI/EurMcwi (MCW), ACI/EurMcwi (ICL)
13 71096742 71096743 A G snv ACI/EurMcwi (MCW), LE/Stm (ICL), SBN/Ygl (ICL), SR/JrHsd (ICL), SS/Jr (ICL), HCR/2Mco (UMich), FHL/EurMcwi (MCW), MHS/Gib (ICL), WKY/NCrl (ICL), F344/NHsd (ICAHN), SR/JrHsd (MCW), COP/CrCrl (MCW & UW), F344/NCrl (ICL), WKY/NHsd (ICL), HCR/1Mco (UMich), WN/N (KNAW), SHR/OlaIpcv (KNAW), SS/JrHsdMcwi (MCW), GH/OmrMcwi (MCW), LL/MavRrrc (ICL), WKY/Gcrc (ICL), DA/BklArbNsi (ICAHN), SHRSP/Gcrc (MDC), F344/NRrrc (KNAW), BUF/N (KNAW), ACI/N (KNAW), SS/JrHsdMcwi (ICL), LN/MavRrrc (ICL), ACI/EurMcwi (ICL), LE/Stm (KNAW), SS/JrHsdMcwi (MDC), SHR/OlaIpcv (ICL), LCR/2Mco (UMich), LCR/1Mco (UMich), LH/MavRrrc (ICL), SHRSP/Gcrc (ICL), FHL/EurMcwi (ICL), SHR/OlaIpcv (ICL), SHR/NHsd (ICL)
13 71099579 71099580 T G snv SR/JrHsd (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735059 AgrOrtholog
Ensembl Genes ENSRNOG00000024849 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000048267 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000039176 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000064775 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071656 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050734 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000071482 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000077874 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12190 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599615 IMAGE-MGC_LOAD
InterPro Lamina-ass_polypeptide_CLAP1C UniProtKB/Swiss-Prot
  LAP1C-like_C_sf UniProtKB/Swiss-Prot
KEGG Report rno:304881 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72610 IMAGE-MGC_LOAD
NCBI Gene 304881 ENTREZGENE
PANTHER PTHR18843 UniProtKB/Swiss-Prot
Pfam LAP1C UniProtKB/Swiss-Prot
PhenoGen Tor1aip2 PhenoGen
UniProt M0R5U6 ENTREZGENE, UniProtKB/TrEMBL
  Q6P752 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Tor1aip2  torsin 1A interacting protein 2  Tor1aip2  torsin A interacting protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tor1aip2  torsin A interacting protein 2  MGC72610  Unknown (protein for MGC:72610)  Symbol and Name updated 1299863 APPROVED
2005-09-30 MGC72610        Symbol and Name status set to provisional 70820 PROVISIONAL