Ier5 (immediate early response 5) - Rat Genome Database

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Gene: Ier5 (immediate early response 5) Rattus norvegicus
Analyze
Symbol: Ier5
Name: immediate early response 5
RGD ID: 69252
Description: Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including cellular response to heat; positive regulation of cellular response to heat; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be part of protein phosphatase type 2A complex. Orthologous to human IER5 (immediate early response 5); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,820,450 - 69,822,542 (-)NCBIGRCr8
mRatBN7.21367,270,134 - 67,272,226 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,270,135 - 67,272,227 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,855,230 - 69,857,322 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,168,972 - 71,171,064 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,429,440 - 68,431,532 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,742,210 - 72,744,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,742,210 - 72,744,303 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,677,760 - 77,679,852 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,058,818 - 70,060,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11370,072,904 - 70,073,288 (-)NCBI
Celera1367,145,754 - 67,147,846 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromuconazole  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
elesclomol  (ISO)
Enterolactone  (ISO)
etoposide  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
testosterone  (EXP)
tetraphene  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification and cataloging of genes induced by long-lasting long-term potentiation in awake rats. Matsuo R, etal., J Neurochem 2000 Jun;74(6):2239-49.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:25816751   PMID:26496226  


Genomics

Comparative Map Data
Ier5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,820,450 - 69,822,542 (-)NCBIGRCr8
mRatBN7.21367,270,134 - 67,272,226 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,270,135 - 67,272,227 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1369,855,230 - 69,857,322 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,168,972 - 71,171,064 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,429,440 - 68,431,532 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,742,210 - 72,744,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,742,210 - 72,744,303 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,677,760 - 77,679,852 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,058,818 - 70,060,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11370,072,904 - 70,073,288 (-)NCBI
Celera1367,145,754 - 67,147,846 (-)NCBICelera
Cytogenetic Map13q21NCBI
IER5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381181,088,700 - 181,092,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1181,088,700 - 181,092,900 (+)EnsemblGRCh38hg38GRCh38
GRCh371181,057,836 - 181,062,036 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,324,261 - 179,326,602 (+)NCBINCBI36Build 36hg18NCBI36
Build 341177,789,294 - 177,791,629NCBI
Celera1154,164,524 - 154,166,865 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1152,288,717 - 152,291,058 (+)NCBIHuRef
CHM1_11182,480,274 - 182,482,615 (+)NCBICHM1_1
T2T-CHM13v2.01180,443,759 - 180,447,959 (+)NCBIT2T-CHM13v2.0
Ier5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,972,113 - 154,975,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1154,972,107 - 154,975,382 (-)EnsemblGRCm39 Ensembl
GRCm381155,096,367 - 155,099,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,096,361 - 155,099,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv371156,943,497 - 156,946,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361156,859,744 - 156,861,854 (-)NCBIMGSCv36mm8
Celera1157,525,763 - 157,529,032 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.45NCBI
Ier5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540620,140,510 - 20,143,147 (+)NCBIChiLan1.0ChiLan1.0
IER5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,681,121 - 68,685,970 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,339,452 - 68,344,615 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,565,169 - 156,569,648 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,231,649 - 160,233,411 (+)NCBIpanpan1.1PanPan1.1panPan2
IER5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,554,184 - 14,557,929 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl714,555,992 - 14,556,930 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha714,133,473 - 14,135,654 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0714,282,236 - 14,284,424 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1714,193,262 - 14,195,449 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0714,299,866 - 14,302,048 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,423,635 - 14,425,831 (+)NCBIUU_Cfam_GSD_1.0
Ier5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,456,183 - 90,458,357 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364818,301,297 - 8,305,082 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IER5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,633,781 - 122,635,948 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,633,781 - 122,635,950 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,670,062 - 134,672,230 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IER5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12548,314,925 - 48,317,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2548,315,871 - 48,316,854 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605549,696,909 - 49,699,233 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ier5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247711,318,498 - 1,319,418 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247711,318,097 - 1,320,394 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ier5
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:59
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000071937
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat

Markers in Region
UniSTS:496740  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21367,271,245 - 67,271,336 (+)MAPPERmRatBN7.2
Rnor_6.01372,743,322 - 72,743,412NCBIRnor6.0
Rnor_5.01377,678,872 - 77,678,962UniSTSRnor5.0
RGSC_v3.41370,059,930 - 70,060,020UniSTSRGSC3.4
Celera1367,146,866 - 67,146,956UniSTS
Cytogenetic Map13q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 20 7 19 7 2 2 74 34 39 11 2
Low 37 34 34 6 9 1 2 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000077157   ⟹   ENSRNOP00000074441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1367,270,135 - 67,272,227 (-)Ensembl
Rnor_6.0 Ensembl1372,742,211 - 72,744,303 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093366   ⟹   ENSRNOP00000076350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1372,742,210 - 72,744,295 (-)Ensembl
RefSeq Acc Id: NM_001025137   ⟹   NP_001020308
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81369,820,450 - 69,822,542 (-)NCBI
mRatBN7.21367,270,134 - 67,272,226 (-)NCBI
Rnor_6.01372,742,210 - 72,744,302 (-)NCBI
Rnor_5.01377,677,760 - 77,679,852 (-)NCBI
RGSC_v3.41370,058,818 - 70,060,910 (-)RGD
Celera1367,145,754 - 67,147,846 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001020308 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074441.1
RefSeq Acc Id: NP_001020308   ⟸   NM_001025137
- UniProtKB: A6ICY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074441   ⟸   ENSRNOT00000077157
RefSeq Acc Id: ENSRNOP00000076350   ⟸   ENSRNOT00000093366

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1W2Q6P5-F1-model_v2 AlphaFold A0A1W2Q6P5 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698910
Promoter ID:EPDNEW_R9428
Type:single initiation site
Name:Ier5_1
Description:immediate early response 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01372,744,317 - 72,744,377EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69252 AgrOrtholog
BioCyc Gene G2FUF-17852 BioCyc
Ensembl Genes ENSRNOG00000059406 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077157.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7326120 IMAGE-MGC_LOAD
InterPro IER UniProtKB/TrEMBL
MGC_CLONE MGC:108821 IMAGE-MGC_LOAD
NCBI Gene Ier5 ENTREZGENE
PANTHER IMMEDIATE EARLY RESPONSE GENE 5 PROTEIN UniProtKB/TrEMBL
  PTHR15895 UniProtKB/TrEMBL
Pfam IER UniProtKB/TrEMBL
PhenoGen Ier5 PhenoGen
RatGTEx ENSRNOG00000059406 RatGTEx
UniProt A6ICY3 ENTREZGENE, UniProtKB/TrEMBL
  Q5BK73_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ier5  immediate early response 5      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process functionally involved in long-lasting long-term potentiation in the hippocampus of freely moving rats 68745
gene_regulation up-regulated 75 minutes after LTP induction 68745
gene_regulation regulation is NMDA receptor-dependent 68745