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Gene: Aim2 (absent in melanoma 2) Rattus norvegicus
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Symbol: Aim2
Name: absent in melanoma 2
Description: Predicted to have double-stranded DNA binding activity and identical protein binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of DNA-binding transcription factor activity; and regulation of defense response. Predicted to localize to the AIM2 inflammasome complex; mitochondrion; and nucleoplasm. Orthologous to human AIM2 (absent in melanoma 2); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: MODEL
Also known as: interferon-inducible protein AIM2; LOC304987
Orthologs:
Homo sapiens (human) : AIM2 (absent in melanoma 2)  HGNC  Alliance
Mus musculus (house mouse) : Aim2 (absent in melanoma 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AIM2 (absent in melanoma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aim2 (absent in melanoma 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01391,919,834 - 91,963,080 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,954,138 - 91,962,588 (+)Ensembl
Rnor_5.01396,436,637 - 96,478,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,631,797 - 89,640,265 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11389,820,680 - 89,826,398 (+)NCBI
Celera1385,466,773 - 85,510,053 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Aim2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307283
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.