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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kidney Neoplasms | | ISO | RGD:1354127 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28321044 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kidney Neoplasms | | ISO | RGD:1354127 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28321044 | |
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# | Reference Title | Reference Citation |
1. | Differential distribution of dynamin isoforms in mammalian cells. | Cao H, etal., Mol Biol Cell. 1998 Sep;9(9):2595-609. |
2. | Three dynamin-encoding genes are differentially expressed in developing rat brain. | Cook T, etal., J Neurochem 1996 Sep;67(3):927-31. |
3. | Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. | Evers DM, etal., Nat Neurosci. 2010 Oct;13(10):1199-207. doi: 10.1038/nn.2624. Epub 2010 Aug 29. |
4. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
5. | Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer. | Gray NW, etal., Curr Biol. 2003 Mar 18;13(6):510-5. |
6. | A dynamin-3 spliced variant modulates the actin/cortactin-dependent morphogenesis of dendritic spines. | Gray NW, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1279-90. Epub 2005 Mar 1. |
7. | Dynamin activates NO production in rat renal inner medullary collecting ducts via protein-protein interaction with NOS1. | Hyndman KA, etal., Am J Physiol Renal Physiol. 2011 Apr 13. |
8. | The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons. | Ikeuchi Y, etal., Cell Rep. 2013 Sep 12;4(5):879-89. doi: 10.1016/j.celrep.2013.07.042. Epub 2013 Aug 29. |
9. | Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. | Lu J, etal., Neuron. 2007 Sep 20;55(6):874-89. |
10. | The cytosolic domain of APP induces the relocalization of dynamin 3 in hippocampal neurons. | Meckler X, etal., Eur J Neurosci. 2006 Nov;24(9):2439-43. |
11. | A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis. | Nakata T, etal., J Cell Sci 1993 May;105 ( Pt 1):1-5. |
12. | NCBI rat LocusLink and RefSeq merged data October 15, 2003 | NCBI rat LocusLink and RefSeq merged data October 15, 2003 |
13. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
14. | GOA pipeline | RGD automated data pipeline |
15. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
16. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
17. | Synaptic vesicle endocytosis. | Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645. |
18. | Dynamin isoforms decode action potential firing for synaptic vesicle recycling. | Tanifuji S, etal., J Biol Chem. 2013 Jun 28;288(26):19050-9. doi: 10.1074/jbc.M112.445874. Epub 2013 May 16. |
19. | The role of dynamin 3 in the testis. | Vaid KS, etal., J Cell Physiol. 2007 Mar;210(3):644-54. |
20. | Expression of the endocytic proteins dynamin and amphiphysin in rat gastric enterochromaffin-like cells. | Zanner R, etal., J Cell Sci. 2004 May 1;117(Pt 11):2369-76. |
PMID:10908605 | PMID:12850060 | PMID:14651853 | PMID:14760703 | PMID:16903783 | PMID:19032944 | PMID:21689597 | PMID:21700703 | PMID:23410488 | PMID:23533145 | PMID:23746204 | PMID:26302298 |
PMID:32357304 |
Dnm3 (Rattus norvegicus - Norway rat) |
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DNM3 (Homo sapiens - human) |
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Dnm3 (Mus musculus - house mouse) |
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Dnm3 (Chinchilla lanigera - long-tailed chinchilla) |
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DNM3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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DNM3 (Canis lupus familiaris - dog) |
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Dnm3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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DNM3 (Sus scrofa - pig) |
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DNM3 (Chlorocebus sabaeus - green monkey) |
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Dnm3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Dnm3
2644 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
D13Mit5 |
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D13Mit3 |
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BE116196 |
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AW534587 |
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AA800783 |
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BQ200675 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 7 | 62 | 1 | 7 | 11 | ||||||||
Low | 3 | 39 | 17 | 8 | 19 | 8 | 8 | 9 | 12 | 34 | 34 | 8 | |
Below cutoff | 4 | 29 | 29 | 29 | 2 |
RefSeq Transcripts | NM_138538 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006250141 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006250142 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598662 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598663 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598664 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090311 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090312 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090313 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039090316 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC144674 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AF201839 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
D14076 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000244 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000067653 ⟹ ENSRNOP00000063767 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000075938 ⟹ ENSRNOP00000068044 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000098479 ⟹ ENSRNOP00000085302 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000102382 ⟹ ENSRNOP00000084111 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000104847 ⟹ ENSRNOP00000088404 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000106497 ⟹ ENSRNOP00000088872 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_138538 ⟹ NP_612547 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250141 ⟹ XP_006250203 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006250142 ⟹ XP_006250204 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017598662 ⟹ XP_017454151 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017598663 ⟹ XP_017454152 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017598664 ⟹ XP_017454153 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039090311 ⟹ XP_038946239 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039090312 ⟹ XP_038946240 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039090313 ⟹ XP_038946241 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039090316 ⟹ XP_038946244 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_612547 | (Get FASTA) | NCBI Sequence Viewer |
XP_006250203 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006250204 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017454151 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017454152 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017454153 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946239 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946240 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946241 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038946244 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAF07848 | (Get FASTA) | NCBI Sequence Viewer |
BAA03161 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09406 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09407 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09408 | (Get FASTA) | NCBI Sequence Viewer | |
Q08877 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_612547 ⟸ NM_138538 |
- UniProtKB: | Q9QXL9 (UniProtKB/Swiss-Prot), Q08877 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006250203 ⟸ XM_006250141 |
- Peptide Label: | isoform X5 |
- UniProtKB: | Q08877 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006250204 ⟸ XM_006250142 |
- Peptide Label: | isoform X6 |
- UniProtKB: | Q08877 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_017454152 ⟸ XM_017598663 |
- Peptide Label: | isoform X2 |
- Sequence: |
RefSeq Acc Id: | XP_017454151 ⟸ XM_017598662 |
- Peptide Label: | isoform X1 |
- Sequence: |
RefSeq Acc Id: | XP_017454153 ⟸ XM_017598664 |
- Peptide Label: | isoform X3 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000063767 ⟸ ENSRNOT00000067653 |
RefSeq Acc Id: | ENSRNOP00000068044 ⟸ ENSRNOT00000075938 |
RefSeq Acc Id: | XP_038946239 ⟸ XM_039090311 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_038946240 ⟸ XM_039090312 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_038946241 ⟸ XM_039090313 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_038946244 ⟸ XM_039090316 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | ENSRNOP00000088404 ⟸ ENSRNOT00000104847 |
RefSeq Acc Id: | ENSRNOP00000085302 ⟸ ENSRNOT00000098479 |
RefSeq Acc Id: | ENSRNOP00000084111 ⟸ ENSRNOT00000102382 |
RefSeq Acc Id: | ENSRNOP00000088872 ⟸ ENSRNOT00000106497 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q08877-F1-model_v2 | AlphaFold | Q08877 | 1-869 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698940 | ||||||||
Promoter ID: | EPDNEW_R9464 | ||||||||
Type: | single initiation site | ||||||||
Name: | Dnm3_1 | ||||||||
Description: | dynamin 3 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:727949 | AgrOrtholog |
BioCyc Gene | G2FUF-17683 | BioCyc |
Ensembl Genes | ENSRNOG00000026490 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000063767 | ENTREZGENE, UniProtKB/Swiss-Prot |
ENSRNOP00000068044 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOP00000084111.1 | UniProtKB/TrEMBL | |
ENSRNOP00000085302.1 | UniProtKB/TrEMBL | |
ENSRNOP00000088404 | ENTREZGENE | |
ENSRNOP00000088404.1 | UniProtKB/TrEMBL | |
ENSRNOP00000088872.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000067653 | ENTREZGENE, UniProtKB/Swiss-Prot |
ENSRNOT00000075938 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOT00000098479.1 | UniProtKB/TrEMBL | |
ENSRNOT00000102382.1 | UniProtKB/TrEMBL | |
ENSRNOT00000104847 | ENTREZGENE | |
ENSRNOT00000104847.1 | UniProtKB/TrEMBL | |
ENSRNOT00000106497.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.30.29.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | Dynamin | UniProtKB/TrEMBL |
Dynamin_central | UniProtKB/Swiss-Prot | |
Dynamin_GTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Dynamin_GTPase_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Dynamin_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Dynamin_SF | UniProtKB/Swiss-Prot | |
Dynamin_stalk | UniProtKB/TrEMBL | |
G_DYNAMIN_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GED_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PH-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PH_domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:171574 | UniProtKB/Swiss-Prot |
NCBI Gene | 171574 | ENTREZGENE |
PANTHER | PTHR11566 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Pfam | Dynamin_M | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Dynamin_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PF00169 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Dnm3 | PhenoGen |
PRINTS | DYNAMIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | G_DYNAMIN_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
G_DYNAMIN_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PH_DOMAIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SMART | DYNc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
GED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SM00233 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8I5ZYS4_RAT | UniProtKB/TrEMBL |
A0A8I6A8P1_RAT | UniProtKB/TrEMBL | |
A0A8I6A9X4_RAT | UniProtKB/TrEMBL | |
A0A8I6GCQ8_RAT | UniProtKB/TrEMBL | |
DYN3_RAT | UniProtKB/Swiss-Prot, ENTREZGENE | |
Q9QXL9 | ENTREZGENE | |
UniProt Secondary | Q9QXL9 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2005-07-08 | Dnm3 | dynamin 3 | LOC171574 | testicular dynamin | Symbol and Name updated | 1299863 | APPROVED |
Note Type | Note | Reference |
---|---|---|
gene_expression | expressed in seminferous tubules of testis, in Sertoli cells | 1299610 |